Extensive mass spectrometry-based profiling of polar metabolites within synaptic vesicles that are rapidly isolated either from cultured mouse neurons or directly from mouse brains reveals their neurotransmitter composition.
In mitotically aging yeast cells, the cytosol acidifies, the distances between the organellar membranes decrease dramatically, but crowding on the scale of the average size protein is relatively stable.
Whole-brain in- and outputs of inhibitory and excitatory neurons located in distinct subregions of the mouse insular cortex were mapped using viral-tracing strategies.
A new tool to visualize blood-feeding mosquitoes in high resolution and quantitatively characterize their behavior sheds light on contact-dependent sensing and blood-feeding dynamics of several medically relevant mosquito species.
