Michael Lohse, Oliver M Gauld ... Robert AA Campbell
A validated, open design brings programmable non-invasive photostimulation of multiple cortical areas in behaving mice to labs without expertise in optics or software design.
Pedro Pessoa, Carol Yunxiao Slayton ... Steve Presse
Conventional colony counting obscures bacterial population structure by conflating biological heterogeneity with stochastic noise from dilution and plating, which can be separated by explicitly modeling the measurement process.
A generalizable computational approach automatically identifies individual common marmosets to serve as support for presenting and analyzing behavioral tasks without relying on extensive manual work.
Modularized spike sorting pipelines can identify performance bottlenecks, lower contribution barriers, and enable the development of highly accurate algorithms to turn extracellular recordings into spikes.
The open-source closed-loop system enables mice to learn modulation of cortical activity or movement by providing a platform for testing brain-behavior relationships in motor learning and neurorehabilitation research.
An optimized rabies virus-based methodology enables efficient monosynaptic input mapping and circuit reconstruction from genetically defined neurons in larval zebrafish.
A streamlined seven-component cell-free expression platform simplifies reaction design while maintaining high productivity and enabling robust synthesis of challenging proteins for diverse applications.
Annemiek C Veldsink, Jonas S Fischer ... Liesbeth M Veenhoff
A non-perturbative nanobody-based strategy was developed for pulse-labeling yeast nuclear pore complexes to selectively capture Nup84-containing complexes for imaging and biochemical analysis.