Alessio Paolo Buccino, Arjun Sridhar ... Joshua H Siegle
Parallelized, cloud-compatible pipelines reduce spike sorting of large-scale neural recordings from weeks to hours, and enable systematic benchmarking of algorithms on hybrid data.
Malte Muetter, Daniel C Angst ... Sebastian Bonhoeffer
Tracking luminescent reporter light intensity is a fast, easy way to quantify population decline at high concentrations and tends to be a better proxy for biomass than for cell number.
In contrast to differential expression-based methods, which evaluate and select individual marker genes, CellCover identifies panels of genes that function together to define cell types.
Krassimira A Garbett, James P Allen ... Richard C Sando
Long-term live imaging and tracking approaches reveal a coordination between excitatory and inhibitory synapse assembly, despite continual spatiotemporal dynamics.
Elvi Gil Lievana, Benjamin Arroyo ... Ranier Gutierrez
Making the moment-to-moment dynamics of solid-food intake measurable in any laboratory enables researchers to map the brain circuits that control appetite and accelerate the development of treatments for obesity.
Celldetective is an open-source software integrating segmentation, tracking, and event detection to perform high-throughput end-to-end study of dynamic cell interactions, without requiring coding skills, demonstrated on microscopy immunological assays.
David L Haggerty, Caleb Browning Darden, David Lovinger
Integrated pose estimation, video acquisition, and edge deployment tools make real-time behavioral analysis more accessible to neuroscience laboratories.
David Sidarta-Oliveira, Ana I Domingos, Licio A Velloso
A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and intuitive diagnostics.
