Tools and Resources

A Tools and Resources article allows authors to publish the details of new experimental techniques, datasets, software tools, and other resources.

Latest articles

    1. Developmental Biology and Stem Cells
    2. Genomics and Evolutionary Biology

    A high-resolution mRNA expression time course of embryonic development in zebrafish

    Richard J White et al.
    Global gene expression analysis defines the transcriptional events during the development of zebrafish from fertilised egg to fully formed organism.
    1. Computational and Systems Biology
    2. Neuroscience

    The formation of the light-sensing compartment of cone photoreceptors coincides with a transcriptional switch

    Janine M Daum et al.
    Correlating changes in structure and gene expression in cone photoreceptors of mice daily, between birth and eye opening, created a resource that supports research in photoreceptor function, development, transplantation and repair.
    1. Biophysics and Structural Biology

    Model-based local density sharpening of cryo-EM maps

    Arjen J Jakobi et al.
    Local sharpening of cryo-electron microscopy maps using atomic models can increase the interpretability of densities in cases of resolution variation and facilitates model building and refinement.
    1. Neuroscience

    Neuropathological and transcriptomic characteristics of the aged brain

    Jeremy A Miller et al.
    High variability in neuropathology burden and interactions between dementia diagnosis and RNA quality present underappreciated complications when studying dementia in an aged population.