A crucial component of social cognition is to observe and understand the social interactions of other individuals. A promising nonhuman primate model for investigating the neural basis of social interaction observation is the common marmoset (Callithrix jacchus), a small New World primate that shares a rich social repertoire with humans. Here we used functional magnetic resonance imaging (fMRI) acquired at 9.4 Tesla to map the brain areas activated by social interaction observation in awake marmosets. We discovered a network of subcortical and cortical areas, predominately in the anterior lateral frontal and medial frontal cortex, that was specifically activated by social interaction observation. This network resembled that recently identified in Old World macaque monkeys (Sliwa and Freiwald, 2017). Our findings suggest that this network is largely conserved between New and Old World primates and support the use of marmosets for studying the neural basis of social cognition.
The datasets generated during this study are available at https://github.com/JClery/Social_interaction_paper.
- Stefan Everling
- Stefan Everling
The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.
Animal experimentation: All experimental methods described were performed in accordance with the guidelines of the Canadian Council on Animal Care policy on the care and use of experimental animals and an ethics protocol #2017-114 approved by the Animal Care Committee of the University of Western Ontario.Animals were monitoring during the acquisition sessions by a veterinary technician.
- Thorsten Kahnt, Northwestern University, United States
© 2021, Cléry et al.
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