Skipping ahead: A circuit for representing the past, present, and future
- Department of Psychological and Brain Sciences, Rajen Kilachand Center for Integrated Life Sciences and Engineering, Boston University, United States
- Department of Psychiatry, Douglas Hospital Research Centre, McGill University, Canada
Figures
Figure 1
Direct and indirect pathways connecting the medial prefrontal cortex (mPFC) and the hippocampus.
(A) Monosynaptic pathways between the both dorsal hippocampus (dHPC) and ventral hippocampus (vHPC) and prelimbic (PL) and infralimbic subregions of the mPFC with an anatomical overview of …
Figure 2
Alternating theta cycles provide a framework for imagining or deliberating between future options.
(A) Diagram of the hippocampal formation with examples different cell types recorded across the hippocampus and the medial entorhinal cortex (MEC). (B) Hippocampal time cell sequences in relation to …
Figure 3
Alternating theta cycles provide a framework for alternate representations of future options.
(A) Head direction cell assemblies on alternating theta cycles recorded in the medial entorhinal cortex (MEC). (B) From inputs received from the MEC may support theta sequences of upcoming potential …
Figure 4
Proposed circuit for representation of future scenarios.
The medial prefrontal cortex (mPFC) and nucleus reuniens (NRe) provide unique input to the pre- and parasubiculum, and medial entorhinal cortex on alternating theta cycles. The pre- and …
