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Review Articles are intended to bring readers up-to-date with research on important topics. Review Articles are commissioned by Senior Editors.
Microbiology and Infectious Disease
Antibodies to SARS-CoV-2 and their potential for therapeutic passive immunization
PJ Klasse, John P Moore
Antibodies hold promise for breakthrough treatment of COVID-19, the disease caused by the coronavirus SARS-CoV-2.
Hippocampal remapping as hidden state inference
Honi Sanders et al.
Context representation in the hippocampus incorporates uncertainty and requires inference based on past experience.
Hyperalignment: Modeling shared information encoded in idiosyncratic cortical topographies
James V Haxby et al.
Hyperalignment provides a conceptual framework for cortical architecture that captures how shared information is encoded in idiosyncratic cortical topographies that preserve vector geometry for population response and connectivity patterns.
Mechanisms of competitive selection: A canonical neural circuit framework
Shreesh P Mysore, Ninad B Kothari
A first principles, neuro-computational framework proposes a path for the experimental dissection of neural circuit mechanisms of competitive selection across brain areas and animal species.
Immunology and Inflammation
The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy
Aaron R Lim et al.
Diverse components of the tumor microenvironment affect T cell metabolism in ways that are crucial to improving immunotherapy.
The social life of Norway rats (
Manon K Schweinfurth
Rats are highly social animals that show complex social skills, which has not been acknowledged enough when controlling them in the wild and conducting research in the laboratory.
Prediction signals in the cerebellum: beyond supervised motor learning
Emerging evidence suggests a broad role for cerebellar circuits in generating and testing predictions about movement, reward, and diverse cognitive processes.
Epidemiology and Global Health
The hazards of smoking and the benefits of cessation: a critical summation of the epidemiological evidence in high-income countries
Cumulatively, from 1950 to 2015, smoking-related disease has been the biggest cause of premature death in high-income countries, with elevated risks of smoking continuing well into the 21
A roadmap for gene functional characterisation in crops with large genomes: Lessons from polyploid wheat
Nikolai M Adamski et al.
The development of genomic tools and publicly available resources in polyploid wheat provides a framework to understand biologically important traits in crops with large genomes.
Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies
Ana Rita Pombo Antunes et al.
The heterogeneity of immune cell types in glioblastoma tumors depends on the tumor's genetic make-up and treatment status and is an incompletely mined source of novel therapeutic targets.
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