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Review Articles are intended to bring readers up-to-date with research on important topics. Review Articles are commissioned by Senior Editors.
Prediction signals in the cerebellum: beyond supervised motor learning
Emerging evidence suggests a broad role for cerebellar circuits in generating and testing predictions about movement, reward, and diverse cognitive processes.
Epidemiology and Global Health
The hazards of smoking and the benefits of cessation: a critical summation of the epidemiological evidence in high-income countries
Cumulatively, from 1950 to 2015, smoking-related disease has been the biggest cause of premature death in high-income countries, with elevated risks of smoking continuing well into the 21
A roadmap for gene functional characterisation in crops with large genomes: Lessons from polyploid wheat
Nikolai M Adamski et al.
The development of genomic tools and publicly available resources in polyploid wheat provides a framework to understand biologically important traits in crops with large genomes.
Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies
Ana Rita Pombo Antunes et al.
The heterogeneity of immune cell types in glioblastoma tumors depends on the tumor's genetic make-up and treatment status and is an incompletely mined source of novel therapeutic targets.
Immunology and Inflammation
Preclinical murine tumor models: a structural and functional perspective
Marion V Guerin et al.
Dissecting structural, cellular and molecular differences between transplanted and spontaneous mouse tumor models, highlighting their relevance for predicting the efficacy of anti-cancer treatments in patients.
Resolving homology in the face of shifting germ layer origins: Lessons from a major skull vault boundary
Camilla S Teng et al.
Homology of vertebrate skull structures should be based on evolutionary continuity and an appreciation of germ layer origins and inductive signaling in the embryonic head.
Ten simple rules for the computational modeling of behavioral data
Robert C Wilson, Anne GE Collins
Computational modeling of cognitive and neuroscience data is an insightful and powerful tool, but has many potential pitfalls that can be avoided by following simple guidelines.
Multifaceted roles of microRNAs: From motor neuron generation in embryos to degeneration in spinal muscular atrophy
Tai-Heng Chen, Jun-An Chen
Summary review of microRNA roles during motor neuron generation and degeneration.
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