Review Articles

Review Articles are intended to bring readers up-to-date with research on important topics. Review Articles are commissioned by Senior Editors.

Latest articles

    1. Evolutionary Biology
    2. Neuroscience

    Alone, in the dark: The extraordinary neuroethology of the solitary blind mole rat

    Yael Kashash et al.
    A new ethologically relevant model for investigating the neurobiology of solitary, asocial behavior in the blind mole rat.
    1. Evolutionary Biology
    2. Neuroscience

    Proposing a neural framework for the evolution of elaborate courtship displays

    Ryan W Schwark et al.
    The midbrain periaqueductal grey is a conserved mediator of elaborate courtship behavior in a range of vertebrate taxa, likely shaping how this behavior diversifies across the tree of life.
    1. Neuroscience

    Contractile force assessment methods for in vitro skeletal muscle tissues

    Camila Vesga-Castro et al.
    A standardized comparison of contractile force among in vitro muscle tissues across different platforms requires proper normalization with the contractile area and complementary morphological, maturation, and functional analysis to reduce variability and boost a new generation of engineered constructs.
    1. Medicine

    Post-acute sequelae of COVID-19: A metabolic perspective

    Philipp E Scherer et al.
    The potential metabolic mechanisms that underly the growing prevalence of long COVID are explored and potential treatments discussed.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Primate malarias as a model for cross-species parasite transmission

    Marina Voinson et al.
    Ecological and evolutionary perspectives are critical to understand, predict, prevent, and treat malaria parasites that may spread to humans from our close primate relatives.
    1. Cell Biology

    Female fertility and the zona pellucida

    Paul M Wassarman, Eveline S Litscher
    The ZP is a viscoelastic ECM that provides stability for contacts between projections from the innermost cumulus cells and oocyte microvilli that pass through the ZP and form gap junctions shown to be essential for oocyte growth and follicle development.
    1. Biochemistry and Chemical Biology

    Immunomodulatory drug discovery from herbal medicines: Insights from organ-specific activity and xenobiotic defenses

    Jue Shi et al.
    Organ-selective drug action of traditional Chinese medicine that generates systemic immune mediators is proposed and reviewed as a novel mechanistic angle to develop new immunomodulatory drugs.
    1. Cell Biology

    The right time for senescence

    Diogo Paramos-de-Carvalho et al.
    A time-gated model is proposed to reconcile the transient vs. persistent biological activities of cellular senescence, in which 'time' seems to be the main orchestrator of the beneficial vs. detrimental effects of the senescent programme.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    The influence of biological and lifestyle factors on circulating cell-free DNA in blood plasma

    Nicole Laurencia Yuwono et al.
    Circulating cell-free DNA studies should control for participants' physical activity to avoid its confounding effect on total cell-free DNA level.
    1. Neuroscience

    Skipping ahead: A circuit for representing the past, present, and future

    Jennifer C Robinson, Mark P Brandon
    A circuit between the hippocampus, nucleus reunions, and prefrontal cortex organizes information about the past, present, and future into alternating theta sequences.