Transport of proteins (red) in the cell is a combination of diffusion and polar transport. Diffusion occurs throughout the cytoplasm. When diffusing proteins encounter motor proteins (black arrows) … see more
(A) Sample steady-state configuration obtained from the direct simulation of the polar transport model in a spherical cell with 1000 proteins (red). Direction of polar transport on the surface of … see more
(A) Configuration of the proteins obtained from simulation of the polar transport model with 1000 proteins (red circles). Directed transport on the surface of the cell is along positive z-direction. … see more
(A) Configuration of the proteins obtained from simulation of the polar transport model in a spheroidal cell of radius R=10μm and major axis a=20μm, and 1000 proteins. Direction of transport on the surface … see more
(A) Protein concentration gradients (normalized by the average cytoplasmic concentration c0) in spherical cells of different radii, computed by simulations of the polar transport model with 1000 … see more
(A) Concentration gradient obtained from simulation with 1000 proteins for various values of tbound with a spherical cell of radius R=10 μm. All other parameters are the same as in Figure 2. The analytic … see more
Concentration profiles on the surface of spherical cells of different radii, obtained from simulations of the polar transport model of gradient formations. Inset shows the same data, just with the … see more
Concentration profiles with differing source points. We start very close to the pole and move further away. The radius of the sphere is 10 μm, the diffusion constant D=1 μm2/s and the transport speed along … see more
Concentration Profiles in the XY plane for three different distances from the pole. The radius of the sphere is 10 μm, the diffusion constant D=1 μm2/s and the transport speed along the cortex is v=1μm/s.