Physics of Living Systems

Physics of Living Systems

eLife publishes research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Physics of Living Systems

    Learning to predict target location with turbulent odor plumes

    Nicola Rigolli et al.
    Intensity of an odor and timing of its detection are complementary attributes of turbulent plumes and enable robust prediction of the location of a distant target.
    1. Cell Biology
    2. Physics of Living Systems

    Three-dimensional structure of kinetochore-fibers in human mitotic spindles

    Robert Kiewisz et al.
    Comprehensive 3D electron tomography reconstructions of metaphase spindles in human tissue culture cells reveal that kinetochore-fibers broaden as they extend polewards, forming semi-direct connections to the pole, where they preferentially interact with the spindle network.
    1. Physics of Living Systems

    Interplay of surface interaction and magnetic torque in single-cell motion of magnetotactic bacteria in microfluidic confinement

    Agnese Codutti et al.
    Confined magnetotactic bacteria exhibit circling and U-turn trajectories explained by a competition of alignment with a magnetic field and alignment along the confining walls as well as considerable cell-to-cell heterogeneity.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Lactoferricins impair the cytosolic membrane of Escherichia coli within a few seconds and accumulate inside the cell

    Enrico F Semeraro et al.
    The damage of the bacterial cell envelope is found to be only a secondary effect of the antimicrobial activity of lactoferricin derivatives.
    1. Neuroscience
    2. Physics of Living Systems

    Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome

    Murat Yildirim et al.
    Label-free three-photon imaging of whole, uncleared intact organoids generated from Rett syndrome patients show shorter migration distances and slower migration speeds of mutant radially migrating neurons with more tortuous trajectories.
    1. Physics of Living Systems

    Speed variations of bacterial replisomes

    Deepak Bhat et al.
    1. Cell Biology
    2. Physics of Living Systems

    Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status

    Fanny Momboisse et al.
    Combining particle tracking in living cells with statistical analysis demonstrates how the oligomeric organization of cell surface receptor influences their function, a necessary step in the development of drugs targeting specific receptor conformation.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    A biophysical threshold for biofilm formation

    Jenna A Moore-Ott et al.
    A biophysical model of the process by which bacteria transition from the motile planktonic state to the immobilized biofilm state yields testable predictions in terms of two dimensionless parameters, one describing nutrient availability and the other describing cellular dispersal.

Senior editors

  1. Naama Barkai
    Naama Barkai
    Weizmann Institute of Science, Israel
  2. Aleksandra Walczak
    Ecole Normale Superieure, France
  3. See more editors