Physics of Living Systems

Latest articles

1. 1. Physics of Living Systems
   2. Structural Biology and Molecular Biophysics

   Myosin-based regulation of twitch and tetanic contractions in mammalian skeletal muscle

   Cameron Hill et al.
2. 1. Physics of Living Systems

   Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53

   Kaushik Inamdar et al.
3. 1. Physics of Living Systems
   2. Structural Biology and Molecular Biophysics

   Allosteric conformational ensembles have unlimited capacity for integrating information

   John W Biddle et al.

   The effective higher-order binding cooperativities arising from an ensemble of dynamically interchanging conformations are identified and shown to fully describe integration of binding information at thermodynamic equilibrium.
4. 1. Physics of Living Systems

   Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila

   Myron Barber Child VI et al.
5. 1. Cell Biology
   2. Physics of Living Systems

   Variations of intracellular density during the cell cycle arise from tip-growth regulation in fission yeast

   Pascal D Odermatt et al.
6. 1. Evolutionary Biology
   2. Physics of Living Systems

   Functional biology in its natural context: A search for emergent simplicity

   Joy Bergelson et al.

   The time is right to study biological function without stripping systems of their essential eco-evolutionary context.
7. 1. Cell Biology
   2. Physics of Living Systems

   Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm

   Ashwin Nandagiri et al.

   Calculations of flagellar energetics from beating patterns in sperm reveal that internal dissipation by dynein motors and other passive structures within the flagellum significantly exceeds external hydrodynamic dissipation.
8. 1. Physics of Living Systems

   Mesoscale phase separation of chromatin in the nucleus

   Gaurav Bajpai et al.

   Computer simulations show transitions between novel types of chromatin organization (peripheral, central, conventional) depending on chromatin interactions with itself, the lamin and nuclear hydration, measured in recent experiments.
9. 1. Developmental Biology
   2. Physics of Living Systems

   Quantitative analyses reveal extracellular dynamics of Wnt ligands in Xenopus embryos

   Yusuke Mii et al.

   Wnt distribution is regulated by a dynamic exchange of its abundant scaffold-bound and rare freely diffusing populations, providing insights into a conceived dilemma of speed and stability of tissue patterning.
10. 1. Physics of Living Systems

    Symmetry breaking meets multisite modification

    Vaidhiswaran Ramesh, J Krishnan