Physics of Living Systems

Latest articles

1. 1. Physics of Living Systems
   2. Structural Biology and Molecular Biophysics

   High-throughput single-particle tracking reveals nested membrane domains that dictate KRas^G12D diffusion and trafficking

   Yerim Lee et al.
2. 1. Biochemistry and Chemical Biology
   2. Physics of Living Systems

   Optical estimation of absolute membrane potential using fluorescence lifetime imaging

   Julia R Lazzari-Dean et al.

   Fluorescence lifetime imaging microscopy, paired with fluorescent, voltage-sensitive dyes, provides a method for measuring and quantifying membrane potentials of living cells.
3. 1. Physics of Living Systems

   Phylodynamic theory of persistence, extinction and speciation of rapidly adapting pathogens

   Le Yan et al.

   A model of pathogen co-evolving with host population continuously acquiring immunity is used to identify evolutionary parameters allowing pathogen population to persist without going extinct or splitting into independent lineages.
4. 1. Physics of Living Systems

   Plasticity of cell migration resulting from mechanochemical coupling

   Yuansheng Cao et al.

   Computational and experimental studies show that different migration modes of eukaryotic cells are the result of the interplay between signaling waves and cell mechanics.
5. 1. Physics of Living Systems

   Length regulation of multiple flagella that self-assemble from a shared pool of components

   Thomas G Fai et al.
6. 1. Computational and Systems Biology
   2. Physics of Living Systems

   Epistasis and entrenchment of drug resistance in HIV-1 subtype B

   Avik Biswas et al.

   Drug resistance in HIV is the result of mutations, which affect fitness depending on epistatic interactions with the entire sequence background that varies within and between patient populations.
7. 1. Neuroscience
   2. Physics of Living Systems

   A geometric attractor mechanism for self-organization of entorhinal grid modules

   Louis Kang, Vijay Balasubramanian

   The hierarchy of entorhinal grid cell modules with constant scale ratios can self-organize through a new geometrically organized attractor mechanism.
8. 1. Neuroscience
   2. Physics of Living Systems

   The frequency limit of outer hair cell motility measured in vivo

   Anna Vavakou et al.

   The cells in our inner ear commonly believed to provide fast mechanical feedback are too sluggish to follow the vibrations evoked by high-frequency sounds.
9. 1. Cell Biology
   2. Physics of Living Systems

   Myosin II isoforms play distinct roles in adherens junction biogenesis

   Mélina L Heuzé et al.

   Myosin isoforms exhibit different functions in the formation of adherens junctions and the transmission of mechanical forces.
10. 1. Physics of Living Systems

    Surface-to-volume scaling and aspect ratio preservation in rod-shaped bacteria

    Nikola Ojkic et al.

    Rod-shaped bacteria preserve their aspect ratios and surface-to-volume scaling by maintaining a homeostatic balance between the rates of cell elongation and division protein synthesis.