Physics of Living Systems

Latest articles

1. 1. Physics of Living Systems

   Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility

   Elizabeth Eck et al.
2. 1. Physics of Living Systems

   Deciphering the regulatory genome of Escherichia coli, one hundred promoters at a time

   William T Ireland et al.

   A combination of massively parallel reporter assays and mass spectrometry uncovers the regulation of previously unexplored promoters across the Escherichia coli genome.
3. 1. Physics of Living Systems

   Diffusion vs direct transport in the precision of morphogen readout

   Sean Fancher, Andrew Mugler
4. 1. Immunology and Inflammation
   2. Physics of Living Systems

   Label-free imaging of immune cell dynamics in the living retina using adaptive optics

   Aby Joseph et al.

   Immune cell motility and vascular response are imaged in vivo and label free in the CNS for the first time, using high-resolution phase-contrast adaptive optics retinal imaging.
5. 1. Developmental Biology
   2. Physics of Living Systems

   Nuclear crowding and nonlinear diffusion during interkinetic nuclear migration in the zebrafish retina

   Afnan Azizi et al.

   The evolving spatial distribution of nuclei between apical and basal surfaces of the developing retinal neuroepithelium is quantitatively described by a nonlinear diffusion equation accounting for crowding within the tissue.
6. 1. Cell Biology
   2. Physics of Living Systems

   Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution

   Reza Farhadifar et al.

   Stoichiometric interactions between microtubules and cortical force-generators set spindle size, position and dynamics, and its scaling with cell size in nematode species.
7. 1. Developmental Biology
   2. Physics of Living Systems

   Size-dependent patterns of cell proliferation and migration in freely-expanding epithelia

   Matthew A Heinrich et al.

   Epithelia exhibit size-dependent growth dynamics caused by a decoupling between boundary and bulk cellular dynamics that enable robust expansion and drive cell cycling, collective migration, and tissue-spanning vortices.
8. 1. Neuroscience
   2. Physics of Living Systems

   Efficient coding of natural scene statistics predicts discrimination thresholds for grayscale textures

   Tiberiu Tesileanu et al.

   An optimization principle allows natural-image data to predict human sensitivity to synthetic, un-natural textures with multiple gray levels.
9. 1. Computational and Systems Biology
   2. Physics of Living Systems

   Social interactions drive efficient foraging and income equality in groups of fish

   Roy Harpaz, Elad Schneidman

   Analysis and modeling of group behavior of adult zebrafish shows that a specialized social interaction mechanism increases foraging efficiency and equality within groups, under a variety of environmental conditions.
10. 1. Ecology
    2. Physics of Living Systems

    Nutrient levels and trade-offs control diversity in a serial dilution ecosystem

    Amir Erez et al.

    Whereas theories of ecological diversity mostly consider continuously supplied nutrients, a seasonal model uncovers a general mechanism that controls diversity and reconciles conflicting experimental findings.