Physics of Living Systems

Latest articles

1. 1. Physics of Living Systems

   Asymmetric random walks reveal that the chemotaxis network modulates flagellar rotational bias in Helicobacter pylori

   Jyot D Antani et al.

   Asymmetric forward and backward swimming speeds reveal that the rotational bias, and not reversal frequencies, is an appropriate measure of chemotaxis signaling in Helicobacter pylori..
2. 1. Physics of Living Systems
   2. Structural Biology and Molecular Biophysics

   Proofreading through spatial gradients

   Vahe Galstyan et al.

   Theoretical study shows how enzymes can achieve substrate proofreading by taking advantage of existing molecular gradients in the cell while not being endowed with structural features typically required for proofreading.
3. 1. Physics of Living Systems
   2. Stem Cells and Regenerative Medicine

   Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis

   Arne D Hofemeier et al.
4. 1. Neuroscience
   2. Physics of Living Systems

   Random access parallel microscopy

   Mishal Ashraf et al.
5. 1. Computational and Systems Biology
   2. Physics of Living Systems

   Spatial correlations constrain cellular lifespan and pattern formation in corneal epithelium homeostasis

   Lior Strinkovsky et al.

   Rejuvenation of corneal epithelium in homeostasis is determined by the interplay between corneal cells replicative lifespan and the spatial correlation between cell replication and cell removal.
6. 1. Chromosomes and Gene Expression
   2. Physics of Living Systems

   The interplay between asymmetric and symmetric DNA loop extrusion

   Edward J Banigan, Leonid A Mirny

   Models of chromosome compaction by condensins demonstrate that two-sided loop extrusion and long residence times are required for high compaction, suggesting a tight coupling between these two properties in vivo.
7. 1. Cell Biology
   2. Physics of Living Systems

   Graded titin cleavage progressively reduces tension and uncovers the source of A-band stability in contracting muscle

   Yong Li et al.

   Elastic forces generated by the giant protein titin define both passive and active tension of skeletal muscle fibers and protect the sarcomeric myosin filaments from severe disruption during contraction.
8. 1. Physics of Living Systems

   Dynamics of diffusive cell signaling relays

   Paul B Dieterle et al.

   The collective dynamics of cell signaling relays are at once dramatically sensitive to the system dimensionality and insensitive to many biological details.
9. 1. Physics of Living Systems

   Epithelial colonies in vitro elongate through collective effects

   Jordi Comelles et al.
10. 1. Cell Biology
    2. Physics of Living Systems

    Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm

    James F Pelletier et al.

    Live imaging of multiple cytoplasmic networks in frog egg extracts calls for new models for how egg cytoplasm is physically organized during cleavage divisions.