Physics of Living Systems

Latest articles

1. 1. Cell Biology
   2. Physics of Living Systems

   Convergent Cellular Adaptation to Freeze-Thaw Stress via a Quiescence-like State in Yeast

   Charuhansini Tvishamayi, Farhan Ali ... Shashi Thutupalli
2. 1. Physics of Living Systems

   Physical constraints and biological regulations underlie universal osmoresponses

   Yiyang Ye, Qirun Wang, Jie Lin

   Theoretical modeling uncovers an unusual acceleration in microbial growth following osmotic shock, driven by the coordinated regulation of osmolyte production and cell-wall synthesis.
3. 1. Computational and Systems Biology
   2. Physics of Living Systems

   A mathematical model for ketosis-prone diabetes suggests the existence of multiple pancreatic β-cell inactivation mechanisms

   Sean A Ridout, Priyathama Vellanki, Ilya Nemenman

   A simple mathematical model, incorporating reversible deactivation of β-cells, can potentially explain the rapid onset and remission of a diabetes subtype, ketosis-prone diabetes.
4. 1. Physics of Living Systems
   2. Structural Biology and Molecular Biophysics

   Polyphosphate discriminates protein conformational ensembles more efficiently than DNA promoting diverse assembly and maturation behaviors

   Saloni Goyal, Divya Rajendran ... Athi N Naganathan

   Polyphosphate, a universal stress response regulator, binds distinctively to different starting ensembles of the same protein leading to either condensates or aggregates that in turn can solubilize or further aggregate, showcasing their ability to finely control the assembly process.
5. 1. Cell Biology
   2. Physics of Living Systems

   Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton

   Takaki Yamamoto, Tomoki Ishibashi ... Tatsuo Shibata
6. 1. Physics of Living Systems

   Toward Stable Replication of Genomic Information in Pools of RNA Molecules

   Ludwig Burger, Ulrich Gerland
7. 1. Microbiology and Infectious Disease
   2. Physics of Living Systems

   Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides

   Ka Kiu Lee, Urszula Łapińska ... Stefano Pagliara

   Sub-populations of non growing bacteria survive treatment with antimicrobial peptides by mounting an efflux response.
8. 1. Neuroscience
   2. Physics of Living Systems

   Responses to membrane potential-modulating ionic solutions measured by magnetic resonance imaging of cultured cells and in vivo rat cortex

   Kyeongseon Min, Sungkwon Chung ... Jang-Yeon Park

   Magnetic resonance imaging, through its sensitivity to ionic environments that modulate membrane potential, enables noninvasive assessment of biological systems.
9. 1. Physics of Living Systems
   2. Evolutionary Biology

   Adaptations in wing morphology rather than wingbeat kinematics enable flight in small hoverfly species

   Camille Le Roy, Nina Tervelde ... Florian T Muijres
10. 1. Physics of Living Systems

    The cytoplasm of living cells can sustain transient and steady intracellular pressure gradients

    Majid Malboubi, Mohammad Hadi Esteki ... Guillaume Charras