Physics of Living Systems

Physics of Living Systems

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Physics of Living Systems

    Modelling collective behavior in groups of mice housed under semi-naturalistic conditions

    Xiaowen Chen, Maciej Winiarski ... Aleksandra M Walczak
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Physics of Living Systems

    Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

    Ken-ichiro F Kamei, Koseki J Kobayashi-Kirschvink ... Yuichi Wakamoto
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Overflow metabolism originates from growth optimization and cell heterogeneity

    Xin Wang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience
    2. Physics of Living Systems

    The Geometry and Dimensionality of Brain-wide Activity

    Zezhen Wang, Weihao Mai ... Quan Wen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Physics of Living Systems

    Emergence of ion-channel-mediated electrical oscillations in Escherichia coli biofilms

    Emmanuel Akabuogu, Victor Carneiro da Cunha Martorelli ... Thomas A Waigh
    Electrical signaling is demonstrated in Escherichia coli biofilms.
    1. Cancer Biology
    2. Physics of Living Systems

    Robust assessment of asymmetric division in colon cancer cells

    Domenico Caudo, Chiara Giannattasio ... Mattia Miotto
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Physics of Living Systems

    A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits

    Krishna Rijal, Pankaj Mehta
    A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical networks with desired input–output relationships.
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli

    Irina Kalita, Ira Alexandra Iosub ... Meriem El Karoui
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Physics of Living Systems

    Modularity of the segmentation clock and morphogenesis

    James E Hammond, Ruth E Baker, Berta Verd
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Ecology
    2. Physics of Living Systems

    Evidence of social learning across symbolic cultural barriers in sperm whales

    Antonio Leitao, Maxime Lucas ... Giovanni Petri
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
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Highlights

    1. Physics of Living Systems

    Flagella: A new kind of beat

    Kirsty Y Wan
    1. Physics of Living Systems

    Cancer: Cells under pressure

    Dhiraj Indana, Ovijit Chaudhuri
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Modelling biomolecular condensates

    Furqan Dar, Rohit Pappu

Senior editors

  1. Felix Campelo
    The Institute of Photonic Sciences, Spain
  2. Aleksandra Walczak
    Ecole Normale Superieure, France
  3. See more editors