Physics of Living Systems

Latest articles

1. 1. Physics of Living Systems

   A minimal self-organisation model of the Golgi apparatus

   Quentin Vagne et al.

   An unbiased model for the self-organisation of the Golgi apparatus displays either anterograde vesicular transport or cisternal maturation depending on ratios of budding, fusion and biochemical conversion rates.
2. 1. Neuroscience
   2. Physics of Living Systems

   Efficient coding of natural scene statistics predicts discrimination thresholds for grayscale textures

   Tiberiu Tesileanu et al.
3. 1. Developmental Biology
   2. Physics of Living Systems

   Cell lineage-dependent chiral actomyosin flows drive cellular rearrangements in early Caenorhabditis elegans development

   Lokesh G Pimpale et al.

   Developmentally controlled chiral counter-rotating actomyosin flows drive cell-lineage spindle skews and cell rearrangements during cytokinesis in early nematode development.
4. 1. Ecology
   2. Physics of Living Systems

   Revealing the structure of information flows discriminates similar animal social behaviors

   Gabriele Valentini et al.

   Information theory reveals that apparently similar signaling behaviors in ants and termites are instead governed by distinct communication protocols explaining their underlying different functions.
5. 1. Physics of Living Systems

   A mechanism for hunchback promoters to readout morphogenetic positional information in less than a minute

   Jonathan Desponds et al.
6. 1. Neuroscience
   2. Physics of Living Systems

   Revealing architectural order with quantitative label-free imaging and deep learning

   Syuan-Ming Guo et al.
7. 1. Cell Biology
   2. Physics of Living Systems

   Golgi compartments enable controlled biomolecular assembly using promiscuous enzymes

   Anjali Jaiman, Mukund Thattai

   By partitioning promiscuous enzymes across multiple Golgi compartments, eukaryotic cells can tightly control the synthesis of complex sugar oligomers.
8. 1. Physics of Living Systems
   2. Structural Biology and Molecular Biophysics

   Dynamic metastable long-living droplets formed by sticker-spacer proteins

   Srivastav Ranganathan, Eugene I Shakhnovich

   Multi-scale simulations reveal a potential, ATP-independent mechanism resulting in the formation of the long-living multi-droplet state by multi-valent, spacer-sticker proteins.
9. 1. Immunology and Inflammation
   2. Physics of Living Systems

   Quantitative modeling of the effect of antigen dosage on B-cell affinity distributions in maturating germinal centers

   Marco Molari et al.

   Detailed and inferred model reproduces B-cell affinity distributions measured in mice immunized according to various protocols and explains non-monotonous effects of antigen dosage on maturation.
10. 1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Phase Separation: Restricting the sizes of condensates

    Furqan Dar, Rohit Pappu

    Computer simulations of model proteins with sticker-and-spacer architectures shed light on the formation of biomolecular condensates in cells.