Physics of Living Systems

Physics of Living Systems

eLife publishes research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Allosteric conformational ensembles have unlimited capacity for integrating information

    John W Biddle et al.
    The effective higher-order binding cooperativities arising from an ensemble of dynamically interchanging conformations are identified and shown to fully describe integration of binding information at thermodynamic equilibrium.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Functional biology in its natural context: A search for emergent simplicity

    Joy Bergelson et al.
    The time is right to study biological function without stripping systems of their essential eco-evolutionary context.
    1. Cell Biology
    2. Physics of Living Systems

    Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm

    Ashwin Nandagiri et al.
    Calculations of flagellar energetics from beating patterns in sperm reveal that internal dissipation by dynein motors and other passive structures within the flagellum significantly exceeds external hydrodynamic dissipation.
    1. Physics of Living Systems

    Mesoscale phase separation of chromatin in the nucleus

    Gaurav Bajpai et al.
    Computer simulations show transitions between novel types of chromatin organization (peripheral, central, conventional) depending on chromatin interactions with itself, the lamin and nuclear hydration, measured in recent experiments.
    1. Developmental Biology
    2. Physics of Living Systems

    Quantitative analyses reveal extracellular dynamics of Wnt ligands in Xenopus embryos

    Yusuke Mii et al.
    Wnt distribution is regulated by a dynamic exchange of its abundant scaffold-bound and rare freely diffusing populations, providing insights into a conceived dilemma of speed and stability of tissue patterning.
    1. Physics of Living Systems

    Symmetry breaking meets multisite modification

    Vaidhiswaran Ramesh, J Krishnan

Senior editors

  1. Naama Barkai
    Naama Barkai
    Weizmann Institute of Science, Israel
  2. Aleksandra Walczak
    Ecole Normale Superieure, France
  3. See more editors