(A) Supplementary datasets for Figure 1E. Original dorsal medial prefrontal cortex (dmPFC) LFP power spectrograms between the target (red) and no target (black) sessions for individual mice shown in Figure 1E (n = 14 wild-type mice). Each line shows each mouse. (B) Phase-amplitude coupling measures for a dmPFC LFP trace in the target session in a typical mouse, shown by contour plots of modulation index for all pairs of high (y-axis, gamma-range) and low (x-axis, theta-range) frequencies. Warm colors indicate stronger modulation. No pronounced coupling was observed. (C) Relationship between the percentages of dmPFC LFP power changes in the target session (corresponding with Figures 1F and 3B) and SI ratios (corresponding with Figure 1B). Each dot represents each mouse (n = 14 wild-type (black), 7 Shank3 knockout (KO) (blue), and 6 defeated (red) mice). In wild-type mice, no significant correlations were found between these variables (Black line). (D) Comparison of moving speed distributions between the no target and target sessions (n = 2086 frames; Z = 20.20, p=9.0 × 10-89, Mann-Whitney U test). (E, F) Comparisons of distributions of LFP power between running (>5 cm/s) and stop (<1 cm/s) periods in the target session (dmPFC, n = 254, and 1,008 frames; 4–7 Hz: Z = 4.93, p=8.26 × 10-7; 30–60 Hz: Z = 2.13, p=0.033; BLA, n = 58, and 519 frames; 4–7 Hz: Z = 2.42, p=0.016; 30–60 Hz: Z = 2.00, p=0.045, Mann-Whitney U test). Asterisks represent significantly higher power. (G) Supplementary datasets for Figure 1F. Comparison of z-scored dmPFC 4–7 Hz (cyan) and 30–60 Hz (magenta) power specifically computed from running periods between the target and no target sessions (n = 14 mice). LFP power at each frequency band was z-scored based on the average and SD of LFP power at each frequency band in an entire period including the no target and target sessions. Data are presented as the mean ± SEM. Each thin line represents each mouse. p>0.05, paired t-test. (H) Same as G but specifically computed from stop periods. * and # represent a significant increase and decrease in the target session, respectively (p<0.05, paired t-test vs no target).