1. Computational and Systems Biology

What fraction of cellular DNA turnover becomes cfDNA?

  1. Ron Sender
  2. Elad Noor
  3. Ron Milo  Is a corresponding author
  4. Yuval Dor  Is a corresponding author
  1. Weizmann Institute of Science, Israel
  2. Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel Canada, the Hebrew University-Hadassah Medical School, Israel
https://doi.org/10.7554/eLife.89321.3
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  1. Ron Sender
  2. Elad Noor
  3. Ron Milo
  4. Yuval Dor
(2024)
What fraction of cellular DNA turnover becomes cfDNA?
eLife 12:RP89321.
https://doi.org/10.7554/eLife.89321.3
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Figure 1
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cfDNA as a fraction of homeostatic cell turnover.

Estimates for the DNA flux from homoeostatic cell turnover were made based on Sender and Milo, 2021 and converted to units of potential cfDNA plasma concentration (see Methods). Cell types are …

Additional files

Source data 1

Summary of the data used for the comparison: cfDNA properties and cell-type specific cellular turnover data.

https://cdn.elifesciences.org/articles/89321/elife-89321-data1-v1.xlsx
MDAR checklist
https://cdn.elifesciences.org/articles/89321/elife-89321-mdarchecklist1-v1.pdf

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