(A) The floor of the arena is 120 cm in diameter, and the walls are 45 cm tall. Note 20 cm scale bar in this panel. The home cage has a 10.5x6.5 cm2 floor area. The door slides upward (mice enter …
(A) Example trajectories of a mouse during pretraining (see Materials and methods). The mice are habituated to their home cage (Day 1) and the maze (Day 2, no food). On Day 3, mice start exploring …
(A) Two examples of mouse search trajectories during early learning (trial 3) when the entrance changes from trial to trial. They are irregular and vary unpredictably across trials. (A, B) Star = …
(A) Red bar: hole checks in the target hole (labeled ‘0’). Green shaded bars: hole checks in the previous positions of the target in the mouse’s perspective (see Figure 1—figure supplement 1B; ‘–1’ …
(A) Two examples of mouse search trajectories during early learning (trial 3). They are irregular and variable similarly to those in the random entrance experiments. (A, B) Star = target location. …
(A) Pink spots: hole checks in the last 3 s before finding the target; gray spots: earlier hole checks. Dashed ellipsis (x=mean): dispersion (covariance) of the spatial distribution of hole checks. …
Arenas on the top row (mean displacement vector – see color scale between panels B and E) correspond to the ones immediately below them (hole checking spatial distribution); the red ‘A’ label marks …
(A) Observed trajectory with hole-checking events identified by the two criteria sets of our method, applied subsequently to avoid missed checks. (B) The velocity profile with dots representing the …
The jackknife sampling procedure is obtained by the ‘leave-one-out’ rule, yielding N unique jackknife samples of N-1 points from an original sample of N points (see Materials and methods). (A) …
(A) Definition of the geometric features that measure performance across trials. Food line: the straight line that connects the food hole (target) to the entrance; this line defines the optimal …
The definition of each of these parameters is given in Figure 4—figure supplement 3. Small filled symbols = average over trajectory for each mouse; large empty symbols = average over mice (N=8) of …
(A) Comparison in learning rate between mice with 2D cues on the wall (blue) and mice with no cues (red). N=4 mice per group, Error = SE. No significant difference in performance. (B) Example …
Mice are trained in the static entrance protocol to find food at the target labeled ‘A’ (blue circle), and a probe trial is executed with mice entering from a rotated entrance after 18 trials. (A, …
(A-D) Trajectory exemplars of four sequential stages of the experiment (all trials done with static entrance, N=8): (A) training target A (trials 1 A and 16 A for early and late learning, …
Black arrows point to the mean displacement direction starting from any given site in the arena. Panels (A-D) and (H-K) green arrows are the target (food) vectors (point from start to target; or …
(A and B) Black squares are the minimum distances expected by chance for each trial; they are calculated with respect to a random point, and then averaged over ten such random points. Shaded area …
Arenas on the top row (mean displacement vector) correspond to the ones immediately below them (hole checking spatial distribution); the red ‘A’ and blue ‘B’ labels mark the targets (food sites), …
The mouse was first trained with food at Site A (6 days, 18 trials) and, after training was complete, trained with food at Site B (3 days, 9 trials). The video was taken on a probe trial (Day 10) …