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William R Bishai, director of the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), argues that the best place to carry out research into a disease is in its midst.

The biomedical research enterprise in the US has become unsustainable and urgent action is needed to address a variety of problems.

When analysing the data in a two-dimensional scatter plot, researchers should consider plotting the three regression lines that can be calculated for such a plot.

The use of X-rays to investigate why bones break could lead to treatments that reduce the number of elderly people who suffer broken hips.

eLife deputy editor Fiona M Watt recounts some of her personal experiences as a senior female academic in a male-dominated environment.

Eve Marder explains why all scientists should spend time living and working in a foreign country.

Academic review committees would benefit from more details about the contributions made by individual researchers to papers with multiple authors, and also from more information about other types of scholarly communication.

Following a career in science involves long hours and hard work, but as Eve Marder explains in the first of a series of columns, it can also be extremely rewarding.

In his new book Ben Goldacre argues that the pharmaceutical industry is in poor health and in urgent need of treatment.