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  1. Fighting antibiotic resistance

    Certain antibiotic regimens may drive the emergence of antibiotic resistance genes in gut bacteria, while others may reduce resistance especially when used for longer periods.
  2. Triple threat to rare muscle diseases

    A new pipeline tests chemicals on three different animal models, accelerating drug discovery for a muscle disease with no treatment.
  3. Controlled access

    Molecular imaging reveals how two similar protein regions link together to regulate stem cells.
  4. Fighting fungi

    Combining commonly used drugs with an antifungal medication can help or hinder the treatment of serious fungal infections.
  5. Could some antibiotics be immune stimulants?

    Bedaquiline, a recently approved anti-tuberculosis drug, also turns immune cells called macrophages into efficient bacteria-killing machines.
  6. Don’t blame it on catalysis

    The histone-modifying protein Epe1 may moonlight as an enzyme in yeast, but it does not require catalytic activity to do its main job.
  7. Danger is coming!

    A study in mice provides insights into how animals detect and respond to upcoming threats.
  8. How to plug a leak in the eye

    Leaky blood vessels in the back of the eye can cause blindness, but this can be stopped in mice by selectively targeting proteins that regulate blood vessel growth.