The spiking activity of the subthalamic nucleus, rather than the activity of striatal projection neurons, orchestrates basal ganglia downstream activity and output commands in health and Parkinson’s disease.

Negative feedback signals within the substantia nigra regulate the output of the basal ganglia, with implications for disorders such as Parkinson's disease.

A model based on the architecture of basal ganglia and validated with behavior and neuroimaging distinguishes mechanisms of action cancellation from no-go decisions.

The cerebellum sends a functional input to the song-related basal ganglia via the thalamus in songbirds that can modify premotor activity, and it participates to song learning in juvenile birds.

The basal ganglia may preferentially influence movements based on internal goals rather than those guided by external stimuli.

Rats are slower to initiate actions when these actions may need to be cancelled, and this slowing is associated with increased and more variable neural firing in the substantia nigra pars reticulata.

A novel connection from ventral striatum to motor cortex enables emotion and motivation to influence action and motor control.

Gene manipulation combined with behavior analysis reveals a role of miR-9 in modulating basal-ganglia-dependent developmental vocal learning and adult vocal performance via regulating the FOXP1/FOXP2 gene network and dopamine signaling in songbirds.

Experimental data and computational simulations reveal a new functional model, that is 'Triple-control' for the basal ganglia pathways in action selection.

Activity in cortico-basal ganglia circuits of juvenile songbirds reflects evaluative signals necessary for comparing self-generated behavior to a goal representation during skill learning.