439 results found
    1. Neuroscience

    Schema-based predictive eye movements support sequential memory encoding

    Jiawen Huang, Isabel Velarde ... Christopher Baldassano
    The development of knowledge for a board game facilitates memory for sequences in the game, demonstrating a new mechanism for the facilitation by enabling complicated predictions.
    1. Neuroscience

    Schema representations in distinct brain networks support narrative memory during encoding and retrieval

    Rolando Masís-Obando, Kenneth A Norman, Christopher Baldassano
    Neural representations of both general event schemas and story-specific details predict memory performance in narrative recall, with distinct brain networks tracking schematic information during perception versus retrieval.
    1. Neuroscience

    Astrocyte and L-lactate in the anterior cingulate cortex modulate schema memory and neuronal mitochondrial biogenesis

    Mastura Akter, Mahadi Hasan ... Ying Li
    Astrocytic Gi pathway activation in the anterior cingulate cortex impairs schema memory and neuronal mitochondrial biogenesis, which can be rescued by exogenous L-lactate administration directly into the area.
    1. Neuroscience

    Schematic memory components converge within angular gyrus during retrieval

    Isabella C Wagner, Mariët van Buuren ... Guillén Fernández
    Upon retrieval, the angular gyrus recombines distinct, consolidated schema components into one memory representation.
    1. Neuroscience

    Development of schemas revealed by prior experience and NMDA receptor knock-out

    George Dragoi, Susumu Tonegawa
    Novel spatial representations by hippocampal cellular assemblies develop on the framework of preconfigured hippocampal networks whose homeostatic synaptic reorganization is accelerated by prior experience and CA3 NMDAR-dependent plasticity.
    1. Medicine
    2. Neuroscience

    CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury

    Nicole A Terpolilli, Reinhard Dolp ... Nikolaus Plesnila
    High mortality following traumatic brain injury in mice carrying a human mutation for familial hemiplegic migraine type 1 (FHM1) is caused by a decreased threshold for cortical spreading depolarizations (CSDs) and subsequent brain edema formation.

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