In the first study attempting to formally quantify the deleterious impact of research misconduct on funding sources and publication output, we found that misconduct accounts for a small but substantial portion of American biomedical science funding dollars and damages the productivity and rate of funding acquisition of those who commit misconduct.

Strategies to improve public trust in biomedical research are being hindered by a scientific mindset that stifles interest in reform.

Job insecurity is putting stress on early-career researchers in Australia, compromising their career development and potentially reducing the quality of research.

Researchers are undertaking a systematic assessment of the reproducibility of biomedical science in Brazil.

The Reproducibility for Everyone initiative aims to provide researchers at all career stages and across many disciplines with training in reproducible research practices via customizable workshop material.

The National Institutes of Health needs to make radical changes to ensure that biomedical research continues to thrive in the United States.

Improving the research culture of an institution may lead to a fairer, more rewarding and successful environment, but how do you start making changes?