Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Immunology and Inflammation

    G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

    Esther Liu, Matthew Wright ... Jennie Lin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Genetics and Genomics

    Impact of Maximal Overexpression of a Non-toxic Protein on Yeast Cell Physiology

    Yuri Fujita, Shotaro Namba ... Hisao Moriya
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics

    Leonid Peshkin, Enrico maria Daldello ... Catherine Jessus
    A comprehensive resource describes protein abundance and phosphorylation dynamics during Xenopus oocyte maturation, serving as an essential tool for investigating the molecular mechanisms driving meiotic progression.
    1. Cell Biology
    2. Physics of Living Systems

    Convergent Cellular Adaptation to Freeze-Thaw Stress via a Quiescence-like State in Yeast

    Charuhansini Tvishamayi, Farhan Ali ... Shashi Thutupalli
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    C-terminal tagging, transmembrane domain hydrophobicity, and an ER retention motif influence the secretory trafficking of the inner nuclear membrane protein emerin

    Jessica Mella, Regan Volk ... Abigail Buchwalter
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke

    Tingbo Li, Ling Yang ... Jie-Min Jia
    Changes in the pericyte pool after stroke affect the restoration of the blood-brain barrier function and brain self-repair, and offer a new approach to therapy.
    1. Cell Biology
    2. Developmental Biology

    Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

    Robert N Rainey, Sam D Houman ... Neil Segil
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

    Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan
    Complementary biochemical and cell-biological approaches reveal that formin FHOD3-mediated actin elongation, rather than nucleation, is critical for maintaining cardiomyocyte sarcomeres.
    1. Cell Biology
    2. Developmental Biology

    Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis

    Azali Azlan, Li Zhu, Ryuya Fukunaga
    Sakura is expressed in female germlines, interacts with Otu, and is crucial for germline stem cell renewal and differentiation and oogenesis in Drosophila.
    1. Cell Biology
    2. Neuroscience

    PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

    Shiyi Wang, Ryan Baumert ... Cagla Eroglu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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Highlights

    1. Cell Biology

    Returning aging cells to productivity

    Rachana S Vaidya, Simon Y Tang
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  4. See more editors