Cell Biology

Latest articles

1. 1. Cell Biology
   2. Neuroscience

   Executioner caspase is proximal to Fasciclin 3 which facilitates non-lethal activation in Drosophila olfactory receptor neurons

   Masaya Muramoto, Nozomi Hanawa ... Natsuki Shinoda
2. 1. Cell Biology

   TRPγ regulates lipid metabolism through Dh44 neuroendocrine cells

   Dharmendra Kumar Nath, Subash Dhakal, Youngseok Lee

   TRPγ is essential for maintaining lipid homeostasis in Drosophila melanogaster, linking neuronal regulation to fat metabolism and suggesting potential therapeutic avenues for metabolic disorders.
3. 1. Cell Biology

   Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in male obese mice

   Dan Wu, Venkateswararao Eeda ... Weidong Wang

   Diet-induced obesity, insulin resistance, and proinflammatory macrophage activation and accumulation in adipose tissue can be counteracted through the inhibition of ER stress sensor IRE1alpha.
4. 1. Cell Biology
   2. Neuroscience

   Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival

   Moloy T Goswami, Eric Weh ... Thomas J Wubben
5. 1. Cell Biology

   Nim1-related kinases regulate septin organization and cytokinesis by modulating Hof1 at the cell division site

   Bindu Bhojappa, Anubhav Dhar ... Saravanan Palani
6. 1. Cell Biology
   2. Neuroscience

   CellSeg3D: self-supervised 3D cell segmentation for fluorescence microscopy

   Cyril Achard, Timokleia Kousi ... Mackenzie Weygandt Mathis
7. 1. Cell Biology
   2. Immunology and Inflammation

   UFMTrack, an Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices

   Mykhailo Vladymyrov, Luca Marchetti ... Britta Engelhardt

   The established under-flow migration tracker (^UFMTrack) framework allows for automated and scalable studies of immune cell interactions with and extravasation across endothelial monolayer under flow in vitro.
8. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

   Artem K Velichko, Nadezhda V Petrova ... Omar L Kantidze

   Treacle condensation, driven by alternating charge blocks, facilitates interactions with transcription factors to spatially segregate ribosomal RNA synthesis and processing, while also recruiting TOPBP1 for activation of the rDNA damage response.
9. 1. Cell Biology

   Myristoylated Neuronal Calcium Sensor-1 captures the preciliary vesicle at distal appendages

   Tomoharu Kanie, Roy Ng ... Peter K Jackson

   Neuronal Calcium Sensor-1 (NCS1) is a protein that captures the preciliary vesicle in the early step of the cilium formation.
10. 1. Cell Biology

    A hierarchical pathway for assembly of the distal appendages that organize primary cilia

    Tomoharu Kanie, Beibei Liu ... Peter K Jackson

    Comprehensive analyses of localization, hierarchy, and function of the proteins located at the distal appendages of the centriole.