Cell Biology

Latest articles

1. 1. Cell Biology
   2. Immunology and Inflammation

   A B-cell actomyosin arc network couples integrin co-stimulation to mechanical force-dependent immune synapse formation

   Jia C Wang et al.

   B-cell integrin co-stimulation promotes the formation of an actomyosin network that drives integrin-dependent immune synapse formation and B-cell activation.
2. 1. Cell Biology

   CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression

   Désirée Schatton et al.

   CLUH links growth signaling pathways and mitochondrial metabolism with cell cycle progression by regulating astrin-1 synthesis and stability.
3. 1. Cell Biology

   Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration

   Robert J Tower et al.

   Metabolic supplementation attenuates age-dependent declines in regeneration.
4. 1. Cell Biology

   Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells

   Wenyang Li et al.

   A high-throughput small molecule screen defined compounds that inactivate primary human hepatic stellate cells (HSCs) and led to the identification of nanchangmycin, which regulates intracellular Ca²⁺ levels and the activity of multiple kinases to control HSC fibrotic activity.
5. 1. Cell Biology

   MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass

   Ellen Busschers et al.
6. 1. Cell Biology

   Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca²⁺ signalling to control glucose-dependent insulin secretion

   Dillon Jevon et al.

   The essential role of focal adhesion kinase in locally regulating insulin secretion and calcium responses in pancreatic beta cells is identified through the use of the pancreatic slice technique.
7. 1. Cell Biology

   C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

   Saskia-Larissa Jauch-Speer et al.

   A genome-wide CRISPR/Cas9 knockout screening approach identified C/EBPδ as transcriptional regulator of the alarmins S100A8 and S100A9 during differentiation of monocytes and inflammatory processes in vivo.
8. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in Caenorhabditis elegans

   Haikel Dridi et al.

   The Ryanodine receptor type 1 calcium channels play a critical role in age-related muscle function loss.
9. 1. Cell Biology
   2. Physics of Living Systems

   Zebrafish airinemes optimize their shape between ballistic and diffusive search

   Sohyeon Park et al.

   Mathematical characterization of the shape of cellular protrusions that form cell–cell contacts in tissues reveals the parameters required for optimizing biological functional objectives, like maximizing cell–cell contact and communicating directional information.
10. 1. Cell Biology
    2. Neuroscience

    The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus

    Natasha M Puri et al.

    Dopamine D1 receptor signaling from the Golgi apparatus in murine striatal medium spiny neurons is regulated by monoamine transporter OCT2.