Cell Biology

Cell Biology

eLife publishes research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we publish and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Neuroscience

    Desmosomal connectomics of all somatic muscles in an annelid larva

    Sanja Jasek, Csaba Verasztó ... Gáspár Jékely
    Volume-EM reconstruction of a whole-body desmosomal connectome including all muscles and their desmosomal partners in a Platynereis larva provides a detailed view of the organisation of the entire locomotor system in an animal.
    1. Cell Biology
    2. Neuroscience

    Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers

    Shenjie Wu, Nancy C Hernandez Villegas ... Randy Schekman
    A pathway of unconventional secretion for alpha-synuclein, a protein which may spread in the brain as part of the pathology of Parkinson’s disease.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle

    Hirotaka Araki, Shinjiro Hino ... Mitsuyoshi Nakao
    Lysine-specific demethylase-1 acts as an epigenetic barrier against glucocorticoid-induced atrophy and exercise-induced hypertrophy in skeletal muscle.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Structures of human dynein in complex with the lissencephaly 1 protein, LIS1

    Janice M Reimer, Morgan E DeSantis ... Andres E Leschziner
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)

    Michael J Rale, Brianna Romer ... Sabine Petry
    An evolutionarily conserved protein sequence present in diverse species like yeast, frogs, chickens, and humans binds a well-known template for microtubule nucleation, the gamma-tubulin ring complex, activating and enhancing its ability to nucleate microtubules, even under low tubulin concentrations.
    1. Cell Biology

    A CRISPR-screen in intestinal epithelial cells identifies novel factors for polarity and apical transport

    Katharina MC Klee, Michael W Hess ... Lukas A Huber

Senior editors

  1. Marianne E Bronner
    Marianne E Bronner
    California Institute of Technology, United States
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  4. See more editors