Cell Biology

Latest articles

1. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Telomeric double-strand DNA-binding proteins DTN-1 and DTN-2 ensure germline immortality in Caenorhabditis elegans

   Io Yamamoto et al.

   The discovery of non-canonical telomeric dsDNA-binding proteins in Caenorhabditis elegans reveal their contribution in the maintenance of telomere length and germline immortality.
2. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   ARL3 activation requires the co-GEF BART and effector-mediated turnover

   Yasmin ElMaghloob et al.

   BART is a co-GEF for ARL3 and maintains the active ARL3-GTP until it is recycled by ARL3 effectors.
3. 1. Cell Biology
   2. Computational and Systems Biology

   Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells

   Peter Jan Hooikaas et al.

   Kinesin-4 KIF21B promotes rapid reorientation of the microtubule network during formation of immunological synapse in T cells by acting as a pausing and catastrophe-inducing factor that keeps microtubules short.
4. 1. Cell Biology
   2. Immunology and Inflammation

   Deep-learning-based three-dimensional label-free tracking and analysis of immunological synapses of CAR-T cells

   Moosung Lee et al.

   Rapid, label-free, volumetric, and automated assessment of the immunological synapse dynamics is demonstrated by combining optical diffraction tomography and deep-learning-based segmentation, providing a new option for immunological research.
5. 1. Cell Biology
   2. Developmental Biology

   The ESCRT machinery regulates retromer-dependent transcytosis of septate junction components in Drosophila

   Hendrik Pannen et al.

   A novel role of endosomal machineries retromer and ESCRT in membrane delivery of Drosophila septate junction components is required for maintenance of junction integrity and epithelial barrier function.
6. 1. Cell Biology
   2. Evolutionary Biology

   A flagellate-to-amoeboid switch in the closest living relatives of animals

   Thibaut Brunet et al.
7. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Ca²⁺ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon

   Salah A Baker et al.

   An optogenetic dual-color Ca²⁺-imaging approach shows how submucosal pacemaker-cells, interstitial cells of Cajal, modulate smooth-muscle responses and drive colonic motility via complex Ca²⁺ signaling.
8. 1. Cell Biology

   Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

   Alexander J Sercel et al.
9. 1. Cell Biology

   Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells

   Andrea Cipriano et al.
10. 1. Cell Biology

    BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes

    Laura Bel Borja et al.

    BUB-1 recruits PP2A/B56 to regulate chromosome congression in meiosis I.