Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Novel mechanism for tubular injury in nephropathic cystinosis

    Swastika Sur, Maggie Kerwin ... Minnie M Sarwal
    ATP6V0A1 was identified as a key player in nephropathic cystinosis-related renal pathology, with antioxidants like ATX emerging as potential treatments to restore V0A1 expression, mitochondrial function, and balance autophagic processes.
    1. Cell Biology
    2. Developmental Biology

    Rediscovering the rete ovarii, a secreting auxiliary structure to the ovary

    Dilara N Anbarci, Jennifer McKey ... Blanche Capel
    The rete ovarii is a complex secretory structure that may play an important role in ovarian homeostasis.
    1. Cell Biology
    2. Developmental Biology

    Ovarian Biology: Revisiting the rete ovarii

    Yan Zhang, Hua Zhang
    Long thought to have little relevance to ovarian physiology, the rete ovarii may have a role in follicular dynamics and reproductive health.
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development

    Divyesh Joshi, Preeti Jindal ... Maneesha S Inamdar
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Genetics and Genomics

    Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain

    Rubina Dad, Yujuan Wang ... Hui-Yuan Wu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons

    Giulia Di Bartolomei, Raul Ortiz ... Peter Scheiffele
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Physics of Living Systems

    A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits

    Krishna Rijal, Pankaj Mehta
    A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical networks with desired input–output relationships.
    1. Cell Biology
    2. Developmental Biology

    Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition

    Yuhkoh Satouh, Takaki Tatebe ... Ken Sato
    Imaging and correlative light and electron microscopy analyses of endosomal-lysosomal organellar assembly in mammalian oocytes elucidated statistic alteration in their size, distribution, and correlation with endo-lysosomal maturation during oocyte-to-embryo transition.
    1. Cell Biology
    2. Developmental Biology

    The full length BEND2 protein is dispensable for spermatogenesis but required for setting the ovarian reserve in mice

    Yan Huang, Nina Bucevic ... Ignasi Roig
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    Zebrafish live imaging reveals a surprisingly small percentage of spinal cord motor neurons die during early development

    Hao Jia, Hongmei Yang, Kathy Qian Luo
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. David James
    University of Sydney, Australia
  4. See more editors