Cell Biology

Cell Biology

eLife publishes research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we publish and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

    Alison K Gillingham et al.
    Relocation of Rab, Ras and Rho family GTPases to the surface of mitochondria enables efficient identification of their effectors, exchange factors and GAPs by proximity biotinylation.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Translational regulation of protrusion-localized RNAs involves silencing and clustering after transport

    Konstadinos Moissoglu et al.
    RNAs enriched at cell protrusions are translated regardless of their location in the cytoplasm but are dynamically repressed in retracting protrusions and incorporated into heterogeneous RNA clusters.
    1. Cancer Biology
    2. Cell Biology

    A positive feedback loop between Myc and aerobic glycolysis sustains tumor growth in a Drosophila tumor model

    Kenneth Kin Lam Wong et al.
    Specific molecular links that orchestrate growth signals and metabolic reprogramming to achieve tumorigenesis are identified as potential metabolic vulnerabilities in cancer treatment.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

    Alexander JR Booth et al.
    Live-cell imaging shows that the contractile acto-myosin network on the nuclear envelope remnant positions chromosomes in early mitosis to ensure efficient and correct interactions between chromosomes and the mitotic spindle.
    1. Cell Biology

    The transcription factor Hey and nuclear lamins specify and maintain cell identity

    Naama Flint Brodsly et al.
    Hey together with LaminC continuously supervise nuclear organisation and differentiated enterocyte identity, a regulation that is lost upon ageing, resulting in loss of gut homeostasis.
    1. Cell Biology
    2. Neuroscience

    Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

    Andrea KH Stavoe et al.
    The dynamic phosphorylation of autophagy component WIPI2B is critical to maintain autophagosome biogenesis in neurons, and ectopic expression of WIPI2B can restore rates of autophagosome biogenesis in aged neurons.

Highlights

    1. Cell Biology
    2. Microbiology and Infectious Disease

    A nuclear passport for HIV

    Lorena Zuliani-Alvarez, Greg J Towers
    1. Cell Biology

    COPII vesicles and starving cells

    Catherine Rabouille

Senior editors

  1. Anna Akhmanova
    Anna Akhmanova
    Utrecht University, Netherlands
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. Suzanne R Pfeffer
    Stanford University School of Medicine, United States
  4. See more editors