Cell Biology

Latest articles

1. 1. Cell Biology

   The yeast H⁺-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H⁺-coupled nutrient uptake

   Elie Saliba et al.

   The H+ influx coupled to nutrient uptake and the plasma membrane H+-ATPase are central actors of the activation of target of rapamycin complex 1 (TORC1) in budding yeast Saccharomyces cerevisiae..
2. 1. Cell Biology

   Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

   Gian-Luca McLelland et al.
3. 1. Cell Biology
   2. Chromosomes and Gene Expression

   A compartmentalized signaling network mediates crossover control in meiosis

   Liangyu Zhang et al.

   A regulatory circuit that localizes to the synaptonemal complex, a liquid crystalline compartment between chromosomes, ensures crossing-over while limiting the number of crossovers between homologous chromosomes during meiosis.
4. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis

   Michael Taschner et al.
5. 1. Cell Biology

   Myotubularin related protein-2 and its phospholipid substrate PIP₂ control Piezo2-mediated mechanotransduction in peripheral sensory neurons

   Pratibha Narayanan et al.

   Local Mtmr2 activity and PI(3,5)P2 abundance dynamically control Piezo2-dependent mechanotransduction in peripheral sensory neurons.
6. 1. Cell Biology

   Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules

   Maud Martin et al.

   Non-centrosomal microtubules are required for endothelial polarization and sprouting, while centrosomally anchored microtubule arrays are both dispensable and insufficient for these processes.
7. 1. Cell Biology

   Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes

   Michelle E Maxson et al.

   The diffusional barrier formed between phagocyte integrin and fungal glucans preserves the microbiostatic phagocytic environment generated during the frustrated phagocytosis of Candida albicans hypha.
8. 1. Cancer Biology
   2. Cell Biology

   Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior

   Rochelle Shirin Sadeghi et al.
9. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling

   Yosuke Yoneyama et al.

   IRS-1, a canonical signaling mediator of IGF-I receptor, serves as an endocytic regulator of IGF-I receptor to facilitate the sustained IGF signaling.
10. 1. Cell Biology
    2. Developmental Biology and Stem Cells

    An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein

    Pooran Singh Dewari et al.