Cell Biology

Latest articles

1. 1. Cell Biology

   Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction

   Laura Le Pelletier et al.

   Aging is associated with stress-induced senescence of adipose stromal cells, leading to impaired adipogenesis, oxidative stress, mitochondrial dysfunction, and insulin resistance, all being alleviated by metformin treatment of adipose stromal cells.
2. 1. Cell Biology
   2. Medicine

   An experimental test of the effects of redacting grant applicant identifiers on peer review outcomes

   Richard Nakamura et al.
3. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Human Erbb2-induced Erk activity robustly stimulates cycling and functional remodeling of rat and human cardiomyocytes

   Nicholas Strash et al.
4. 1. Cell Biology
   2. Developmental Biology

   Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope

   Robert Becker et al.

   Myogenin promotes centrosome attenuation and establishes the nuclear envelope as the dominant microtubule organization center via the scaffold protein AKAP6, which is required for the recruitment of centrosomal proteins.
5. 1. Cell Biology

   Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids

   Thomas M Rawlings et al.

   The study of embryo-endometrial interactions in assembloid co-cultures identifies novel mechanisms of reproductive failure.
6. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

   Vinay V Eapen et al.

   A combination of spatial proteomic and autophagic flux approaches was used to reveal the landscape of turnover of damaged lysosomes, demonstrating a key role for the autophagy receptor TAX1BP1 and its associated kinase TBK1 in both HeLa cells and iNeurons.
7. 1. Cell Biology
   2. Neuroscience

   Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

   Shahzad S Khan et al.
8. 1. Cell Biology

   Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

   Hiroko Katsuno-Kambe et al.
9. 1. Cell Biology

   Endometrium: Preparing for implantation

   J Julie Kim

   A new laboratory model helps to understand the role of senescent cells in fostering a uterine environment that can support an embryo.
10. 1. Cell Biology

    A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

    Minseong Kim et al.

    HGF-MET signaling phosphorylates- and PTPRK dephosphorylates ZNRF3 to regulate ZNRF3 internalization, functioning as a rheostat for Wnt signaling.