Cell Biology

Latest articles

1. 1. Cell Biology

   MIRO1 controls energy production and proliferation of vascular smooth muscle cells

   Lan Qian, Olha M Koval ... Isabella M Grumbach
2. 1. Cell Biology

   Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

   Shivam Shukla, Jessica A Cross ... Mark P Dodding

   Cargo-adaptor binding to the KLC-TPR domains binding triggers structural rearrangements that relieve kinesin-1 autoinhibition, enabling MAP7 recruitment, through an allosteric mechanism that connects cargo recognition to motor activation.
3. 1. Cell Biology

   GTPase-activating protein DLC1 spatio-temporally regulates Rho signaling

   Lucien Hinderling, Max Heydasch ... Olivier Pertz

   Mechanosensitive recruitment of DLC1 to focal adhesions creates a positive feedback loop that locally amplifies Rho activation in response to tension.
4. 1. Cell Biology

   Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy

   Lori B Koch, Tiasha Ghosh ... Adèle L Marston

   A system to enrich yeast in metaphase of mitosis, meiosis I, or meiosis II reveals reduced spindle assembly checkpoint robustness in meiosis I and distinct kinetochore composition and phosphorylation states.
5. 1. Cell Biology
   2. Developmental Biology

   Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension

   Hwa-seon Seo, Deli Yu ... Jianbo Wang
6. 1. Cell Biology

   Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions

   Sunayana Sarkar, Harsha Sharma ... Manish Jaiswal

   A genetic toolkit establishes Drosophila as a tractable metazoan system for systematic interrogation of conserved biological functions of the ancient polymer polyphosphate.
7. 1. Cell Biology
   2. Neuroscience

   CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function

   Longxin Xie, Jessica Merjane ... Christopher J Donnelly
8. 1. Cell Biology

   A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

   Tongtong Xu, Fujun Cao ... Chengjian Zhao
9. 1. Structural Biology and Molecular Biophysics
   2. Cell Biology

   Unbend: Correction of local beam-induced sample motion in cryo-EM images using a 3D spline model

   Lingli Kong, Ximena Zottig ... Nikolaus Grigorieff
10. 1. Cell Biology
    2. Neuroscience

    ATP8B1–TMEM30B Flippase Activity Maintains Stereocilia Lipid Asymmetry Required for Hearing

    Henry N De Hoyos, Sihan Li ... Jung-Bum Shin