Cell Biology

Latest articles

1. 1. Cell Biology

   Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk

   Olga Afonso et al.

   Quantitative live-cell microscopy and molecular perturbations in Drosophila and human cells reveal a crosstalk between molecular 'rulers' (Aurora B) and 'clocks' (Cdk1) that coordinates mitotic exit in space and time.
2. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

   Timo Vögtle et al.
3. 1. Cell Biology

   Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy

   Craig A Nash et al.
4. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary Ca_Vβ subunits

   Travis J Morgenstern et al.

   A novel engineered protein that uncouples electrical signals from downstream biological responses in excitable cells provides a unique investigative tool with potential therapeutic applications.
5. 1. Cancer Biology
   2. Cell Biology

   The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells

   Shaheen Kabir et al.

   Targeting the CRL5 ubiquitin ligase complex in combination with CDK9 or MCL1 inhibition could combat innate and acquired resistance of cancer cells to MCL1-targeting therapeutics.
6. 1. Cell Biology
   2. Developmental Biology

   CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity

   Myo-Hyeon Park et al.
7. 1. Cell Biology
   2. Human Biology and Medicine

   Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

   Kasparas Petkevicius et al.
8. 1. Cell Biology
   2. Neuroscience

   Ataxin-7 and Non-stop coordinate SCAR protein levels, subcellular localization, and actin cytoskeleton organization

   Veronica Cloud et al.

   An unbiased biochemical screen reveals a direct link between gene regulation and actin cytoskeleton remodeling.
9. 1. Cell Biology
   2. Physics of Living Systems

   KymoButler, a deep learning software for automated kymograph analysis

   Maximilian AH Jakobs et al.

   KymoButler is a machine learning approach towards the reliable, quick, and fully automated analysis of the dynamics of fluorescently labelled particles in living cells.
10. 1. Cell Biology
    2. Microbiology and Infectious Disease

    Formin-2 drives polymerisation of actin filaments enabling segregation of apicoplasts and cytokinesis in Plasmodium falciparum

    Johannes Felix Stortz et al.

    Formin-2 controls spatiotemporal polymerisation of actin filaments, a common mechanism used by apicomplexans for effective segregation of essential chloroplast-like organelles called apicoplasts, and additionally for daughter formation in Plasmodium falciparum.