Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation

    Danielle B Buglak, Pauline Bougaran ... Victoria L Bautch
    The nuclear membrane protein SUN1 stabilizes endothelial cell-cell junctions far from the nucleus via regulation of microtubule dynamics and Rho GEF-H1 signaling, revealing long-range cellular communication important for vascular development and function.
    1. Cell Biology

    Defects in lipid homeostasis reflect the function of TANGO2 in phospholipid and neutral lipid metabolism

    Agustin Leonardo Lujan, Ombretta Foresti ... Vivek Malhotra
    TANGO2 emerges as a key regulator of fatty acid metabolism by likely affecting acyl-CoA production and utilization.
    1. Cell Biology
    2. Cancer Biology

    Transferred mitochondria accumulate reactive oxygen species, promoting proliferation

    Chelsea U Kidwell, Joseph R Casalini ... Minna Roh-Johnson
    Transferred mitochondria do not always regulate cell behavior by simply restoring mitochondrial function, but rather, transferred mitochondria are dysfunctional, initiating downstream signaling and proliferation in response to reactive oxygen species.
    1. Cell Biology
    2. Developmental Biology

    Transcriptional drifts associated with environmental changes in endothelial cells

    Yalda Afshar, Feyiang Ma ... M Luisa Iruela-Arispe
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel

    Peter R Strege, Luke M Cowan ... Arthur Beyder
    Force applied to the cell membrane reversibly changes a voltage-insensitive gating step of a prokaryotic voltage-gated sodium channel.
    1. Cell Biology

    Surface curvature and basal hydraulic stress induce spatial bias in cell extrusion

    Cheng-Kuang Huang, Xianbin Yong ... Chwee Teck Lim
    1. Cell Biology

    Identification of Candidate Mitochondrial Inheritance Determinants Using the Mammalian Cell-Free System

    Dalen Zuidema, Alexis Jones ... Peter Sutovsky
    1. Cell Biology
    2. Immunology and Inflammation

    HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation

    Sara Scinicariello, Adrian Soderholm ... Gijs A Versteeg
    HUWE1 indirectly mediates the return to cellular homeostasis after pro-inflammatory responses, which it does by controling the stability of the immune suppressor tristetraprolin.

Senior editors

  1. Anna Akhmanova
    Utrecht University, Netherlands
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. David Ron
    Cambridge University, United Kingdom
  4. See more editors