Cell Biology

Latest articles

1. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Formin-2 drives polymerisation of actin filaments enabling segregation of apicoplasts and cytokinesis in Plasmodium falciparum

   Johannes Felix Stortz et al.
2. 1. Cell Biology

   In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

   Alison K Gillingham et al.

   Relocation of Rab, Ras and Rho family GTPases to the surface of mitochondria enables efficient identification of their effectors, exchange factors and GAPs by proximity biotinylation.
3. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Translational regulation of protrusion-localized RNAs involves silencing and clustering after transport

   Konstadinos Moissoglu et al.

   RNAs enriched at cell protrusions are translated regardless of their location in the cytoplasm but are dynamically repressed in retracting protrusions and incorporated into heterogeneous RNA clusters.
4. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels

   Florian Ullrich et al.
5. 1. Cancer Biology
   2. Cell Biology

   A positive feedback loop between Myc and aerobic glycolysis sustains tumor growth in a Drosophila tumor model

   Kenneth Kin Lam Wong et al.

   Specific molecular links that orchestrate growth signals and metabolic reprogramming to achieve tumorigenesis are identified as potential metabolic vulnerabilities in cancer treatment.
6. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

   Alexander JR Booth et al.

   Live-cell imaging shows that the contractile acto-myosin network on the nuclear envelope remnant positions chromosomes in early mitosis to ensure efficient and correct interactions between chromosomes and the mitotic spindle.
7. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Electroporated recombinant proteins as tools for in vivo functional complementation, imaging, and chemical biology

   Amal Alex et al.
8. 1. Cell Biology

   The transcription factor Hey and nuclear lamins specify and maintain cell identity

   Naama Flint Brodsly et al.

   Hey together with LaminC continuously supervise nuclear organisation and differentiated enterocyte identity, a regulation that is lost upon ageing, resulting in loss of gut homeostasis.
9. 1. Cell Biology
   2. Neuroscience

   Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

   Andrea KH Stavoe et al.

   The dynamic phosphorylation of autophagy component WIPI2B is critical to maintain autophagosome biogenesis in neurons, and ectopic expression of WIPI2B can restore rates of autophagosome biogenesis in aged neurons.
10. 1. Cell Biology
    2. Human Biology and Medicine

    Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness

    Arpit Sharma et al.