Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Endosomal chemokine receptor signalosomes regulate central mechanisms underlying cell migration

    Hyunggu Hahn, Carole Daly ... Alex RB Thomsen
    Cell biological approaches and spatiotemporally resolved proteome profiling demonstrate that the chemokine receptor CCR7 can activate G proteins after being internalized into endosomes, from where it regulates Rac1-dependent chemotaxis.
    1. Cell Biology

    Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences

    Elise Miedlar, Grace E Hamilton ... Trisha N Davis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    ORMDL3 restrains type-I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

    Qi Zeng, Chen Yao ... Shuai Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

    Qian Wang, Hongge Li ... Xin Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Cell Biology

    Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions

    Katarzyna Tutak, Izabela Broniarek ... Krzysztof Sobczak
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    Catalytic growth in a shared enzyme pool ensures robust control of centrosome size

    Deb Sankar Banerjee, Shiladitya Banerjee
    A catalytic growth model in a shared enzyme pool explains robust centrosome size equality and size scaling, offering a unifying model for centrosome maturation dynamics across diverse organisms.
    1. Cell Biology
    2. Evolutionary Biology

    Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

    P Richard J Yulo, Nicolas Desprat ... Heather L Hendrickson
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Ankle2 functions as a regulatory subunit of PP2A and interacts with the endoplasmic reticulum protein Vap33 to promote the dephosphorylation of BAF as part of nuclear reassembly after mitosis.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing their formation in Caenorhabditis elegans

    Bhumil Patel, Maryke Grobler ... Needhi Bhalla
    By regulating the chromosome axis component and meiotic HORMAD, HIM-3, the conserved AAA-ATPase PCH-2 controls the number and distribution of meiotic recombination events.
    1. Cell Biology
    2. Cancer Biology

    PRMT1-Mediated Metabolic Reprogramming Promotes Leukemogenesis

    Hairui Su, Yong Sun ... Xinyang Zhao
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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Highlights

    1. Cell Biology

    Controlling insulin secretion

    Marjan Slak Rupnik
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    The Institute of Photonic Sciences, Spain
  3. Silke Hauf
    Virginia Tech, United States
  4. See more editors