Cell Biology

Latest articles

1. 1. Cell Biology
   2. Physics of Living Systems

   Single-molecule turnover dynamics of actin and membrane coat proteins in clathrin-mediated endocytosis

   Michael M Lacy et al.

   The main proteins of clathrin-mediated endocytosis bind and unbind rapidly, continuously turning over about five times during the formation of an endocytic vesicle in yeast.
2. 1. Cell Biology

   Magnetic resonance measurements of cellular and sub-cellular membrane structures in live and fixed neural tissue

   Nathan H Williamson et al.

   Low-field single-sided magnetic resonance diffusion methods detect and measure permeability of sub-micron compartments which likely include cell processes, organelles, and cellular vesicles within ex vivo mouse spinal cords.
3. 1. Cell Biology
   2. Plant Biology

   Evolutionarily unique mechanistic framework of clathrin-mediated endocytosis in plants

   Madhumitha Narasimhan et al.
4. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways

   Spencer Hill et al.

   Human cullin-RING ligases are buffered to a much greater extent than had been previously appreciated, and the roles of ubiquitin chain extension enzymes are far more nuanced at physiological concentrations.
5. 1. Cell Biology
   2. Developmental Biology

   Stepwise polarisation of developing bilayered epidermis is mediated by aPKC and E-cadherin in zebrafish

   Prateek Arora et al.

   Polarity cascade initiated by aPKC in the periderm is transduced by adherens junction component E-cadherin to the basal epidermis during the development of zebrafish bilayered epidermis.
6. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Cryo electron tomography with volta phase plate reveals novel structural foundations of the 96-nm axonemal repeat in the pathogen Trypanosoma brucei

   Simon Imhof et al.

   Cryo electron tomography provides the first high-resolution 3D axoneme structure from any pathogenic organism, revealing novel structures that support the unique motility of these pathogens through host tissues.
7. 1. Cell Biology
   2. Physics of Living Systems

   Rod nuclear architecture determines contrast transmission of the retina and behavioral sensitivity in mice

   Kaushikaram Subramanian et al.

   Establishing retinal contrast transmission as a novel determinant of mammalian fitness, this research adds functional significance to a prominent exception of nuclear organization, previously described in nocturnal rod photoreceptor cells.
8. 1. Cell Biology
   2. Neuroscience

   Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

   Junjun Zhao et al.
9. 1. Cell Biology
   2. Developmental Biology

   TGFβ signaling is critical for maintenance of the tendon cell fate

   Guak-Kim Tan et al.
10. 1. Cell Biology
    2. Computational and Systems Biology

    Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block

    Jakub Tomek et al.

    A computer model of human cardiomyocyte was produced and validated on independent datasets, overcoming shortcomings of its predecessors, also yielding broadly relevant insights and results on major ionic currents.