Cell Biology

Latest articles

1. 1. Cell Biology
   2. Developmental Biology

   BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD

   Uyen Tran, Andrew J Streets ... Oliver Wessely

   The RNA-binding protein BICC1 can act as a genetic disease modifier for kidney cyst formation, potentially explaining the high variability of disease onset and severity in autosomal-dominant polycystic kidney disease patients.
2. 1. Cell Biology

   PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progression

   Jimena Druker, Hao Jiang ... Angus I Lamond
3. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

   Takashi Hotta, Morgan L Pimm ... Kristen J Verhey

   Three newly developed biosensors demonstrate that the C-terminal tail of α-tubulin does not freely extend from the microtubule surface as widely thought, but rather is inaccessible along most microtubules in cells.
4. 1. Cell Biology

   Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow

   Jing-Xin Feng, Mei-Ting Yang ... Giovanna Tosato
5. 1. Cell Biology

   Large-scale identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage

   Yuta Yamazaki, Keiko Kono
6. 1. Cell Biology

   Suppression of interferon signaling via small-molecule modulation of TFAM

   Dionisia Sideris, Husan Lee ... Lin Lyu

   Small-molecule mitochondrial transcription factor A modulators stabilize mtDNA, preventing cytosolic escape and suppressing cGAS-STING interferon signaling, while improving bioenergetics and fibrosis markers in disease models.
7. 1. Cell Biology

   A high-resolution, easy-to-build light-sheet microscope for subcellular imaging

   John Haug, Seweryn Gałecki ... Kevin M Dean

   An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.
8. 1. Cell Biology
   2. Neuroscience

   AutoMorphoTrack: A modular framework for quantitative analysis of organelle morphology, motility, and interactions at single-cell resolution

   Armin Bayati, Jackson G Schumacher, Xiqun Chen
9. 1. Cancer Biology
   2. Cell Biology

   Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function

   Bei Zhang, Ting Cai ... Zhihao Wu

   The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.
10. 1. Cell Biology

    Specific GPCRs Elicit Unique Extracellular Vesicle MiRNA Array Signatures: An Exploratory Study

    Xiao Shi, Michelle C Palumbo ... Aaron Janowsky