Cell Biology

Latest articles

1. 1. Cell Biology
   2. Developmental Biology

   Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

   Robert N Rainey, Sam D Houman ... Neil Segil
2. 1. Cell Biology
   2. Developmental Biology

   Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

   Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan

   Complementary biochemical and cell-biological approaches reveal that formin FHOD3-mediated actin elongation, rather than nucleation, is critical for maintaining cardiomyocyte sarcomeres.
3. 1. Cell Biology
   2. Developmental Biology

   Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis

   Azali Azlan, Li Zhu, Ryuya Fukunaga

   Sakura is expressed in female germlines, interacts with Otu, and is crucial for germline stem cell renewal and differentiation and oogenesis in Drosophila.
4. 1. Cell Biology
   2. Neuroscience

   PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

   Shiyi Wang, Ryan Baumert ... Cagla Eroglu
5. 1. Cell Biology

   The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the Drosophila gut

   Yueliang Zhang, Sara B Noya ... Amita Sehgal

   The Drosophila microbiome regulates the cycling of gut metabolites in a circadian clock and diet-dependent manner.
6. 1. Cell Biology
   2. Physics of Living Systems

   Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton

   Takaki Yamamoto, Tomoki Ishibashi ... Tatsuo Shibata
7. 1. Cell Biology

   Senescence: Returning aging cells to productivity

   Rachana S Vaidya, Simon Y Tang

   Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
8. 1. Cell Biology

   Forward genetics in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency

   Delaney Kaper, Uroš Radović ... Marc Pilon

   Polyunsaturated fatty acids are not genetically replaceable in the nematode C. elegans and only mutations that help free ferrous ions can boost the activity of a poorly functioning desaturase enzyme.
9. 1. Cell Biology

   Quantitative intra-Golgi transport and organization data suggest the stable compartment nature of the Golgi

   Hieng Chiong Tie, Haiyun Wang ... Lei Lu

   Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.
10. 1. Cell Biology
    2. Medicine

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge

    CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.