Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Physics of Living Systems

    Convergent Cellular Adaptation to Freeze-Thaw Stress via a Quiescence-like State in Yeast

    Charuhansini Tvishamayi, Farhan Ali ... Shashi Thutupalli
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

    David Papadopoli, Ranveer Palia ... Ivan Topisirovic
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    EOLA1, a novel mitochondria-localized protein critical for heart functions via regulating mitochondrial translation

    Xiaoyan Shi, Yangyi Zhang ... Hao Chen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Human receptive endometrial assembloid for deciphering the implantation window

    Yu Zhang, Rusong Zhao ... Han Zhao
    Revised
    Reviewed Preprint v4
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD

    Uyen Tran, Andrew J Streets ... Oliver Wessely
    The RNA-binding protein BICC1 can act as a genetic disease modifier for kidney cyst formation, potentially explaining the high variability of disease onset and severity in autosomal-dominant polycystic kidney disease patients.
    1. Cell Biology

    PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progression

    Jimena Druker, Hao Jiang ... Angus I Lamond
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

    Takashi Hotta, Morgan L Pimm ... Kristen J Verhey
    Three newly developed biosensors demonstrate that the C-terminal tail of α-tubulin does not freely extend from the microtubule surface as widely thought, but rather is inaccessible along most microtubules in cells.
    1. Cell Biology

    Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow

    Jing-Xin Feng, Mei-Ting Yang ... Giovanna Tosato
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Large-scale identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage

    Yuta Yamazaki, Keiko Kono
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Suppression of interferon signaling via small-molecule modulation of TFAM

    Dionisia Sideris, Husan Lee ... Lin Lyu
    Small-molecule mitochondrial transcription factor A modulators stabilize mtDNA, preventing cytosolic escape and suppressing cGAS-STING interferon signaling, while improving bioenergetics and fibrosis markers in disease models.
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Highlights

    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders
    1. Cell Biology
    2. Developmental Biology

    Philosophy of Biology: Knowledge and illusions

    Antony M Jose

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Dominique Soldati-Favre
    University of Geneva, Switzerland
  3. Richard M White
    Ludwig Institute for Cancer Research, University of Oxford, United Kingdom
  4. See more editors