Cell Biology

Latest articles

1. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   TANGO1 membrane helices create a lipid diffusion barrier at curved membranes

   Ishier Raote et al.

   TANGO1 creates a barrier to control lipid and protein flux across fused secretory compartments.
2. 1. Cell Biology
   2. Developmental Biology

   TMEM95 is a sperm membrane protein essential for mammalian fertilization

   Ismael Lamas-Toranzo et al.
3. 1. Cell Biology

   Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans

   Yanan Sun et al.
4. 1. Cell Biology

   Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

   Vincenza Caolo et al.
5. 1. Cell Biology

   The copy-number and varied strength of MELT motifs in Spc105 balance the strength and responsiveness of the Spindle Assembly Checkpoint

   Babhrubahan Roy et al.
6. 1. Cell Biology
   2. Developmental Biology

   Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

   Nuno Costa-Borges et al.

   Maternal spindle transfer is a feasible approach to enhance embryonic developmental of compromised oocytes, which can represent a new strategy for patients with forms of infertility refractory to current treatments.
7. 1. Cell Biology

   Bmal1 integrates mitochondrial metabolism and macrophage activation

   Ryan K Alexander et al.

   Macrophage Bmal1 controls the timing of the glycolytic to oxidative metabolism transition that dictates the extent of Hif-1a activation and the associated inflammatory response.
8. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Plasmodium falciparum translational machinery condones polyadenosine repeats

   Slavica Pavlovic Djuranovic et al.
9. 1. Cell Biology
   2. Neuroscience

   Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses

   Kirby M Donnelly et al.
10. 1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    IP₃ mediated global Ca²⁺ signals arise through two temporally and spatially distinct modes of Ca²⁺ release

    Jeffrey T Lock, Ian Parker

    Cell-wide Ca²⁺ signals that regulate numerous cellular functions comprise dual Ca²⁺ release modes through IP₃ receptors, punctate transients mediated by clustered receptors and spatiotemporally diffuse release through functionally distinct receptors.