Cell Biology

Cell Biology

eLife publishes research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we publish and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Developmental Biology

    Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila

    Hannah J Green et al.
    Integrin and actin associated proteins are resolved into four layers within myofibril attachments, an architecture requiring balanced positive and negative regulation of integrin adhesion with integrated mechanotransduction and actin pathways.
    1. Cell Biology
    2. Developmental Biology

    Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos

    Matthew Richard Johnson et al.
    In early Drosophila embryos, histone H2Av continuously exchanges between cytoplasmic lipid droplets, a process that modulates H2Av import into nuclei and constitutes a novel post-translational strategy to regulate nuclear H2Av levels.
    1. Cell Biology

    Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans

    Nikolay Burnaevskiy et al.
    Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the architecture and membrane interactions of the conserved COMMD proteins

    Michael D Healy et al.
    A structural basis for the assembly of core subunits of the Commander Complex has been discovered.
    1. Cell Biology

    Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

    Tae Yeon Yoo et al.
    Quantitative experiments and theory show that the tension-dependent regulation of NDC80 binding to kinetochore microtubules arises from a combination of the changing Aurora B concentration at NDC80 and the nonlinearity of Aurora B autoactivation.
    1. Cell Biology
    2. Developmental Biology

    Radially patterned cell behaviours during tube budding from an epithelium

    Yara E Sanchez-Corrales et al.
    Quantitative analysis in quasi-3D reveals apically driven cell behaviours that are closely coordinated across the tissue to allow ordered tube invagination through a focal point.

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