Cell Biology

Latest articles

1. 1. Cell Biology
   2. Genetics and Genomics

   Assessment of the Histone Mark-based Epigenomic Landscape in Human Myometrium at Term Pregnancy

   San-Pin Wu, Elvis Quiroz ... Francesco J DeMayo
2. 1. Cell Biology
   2. Genetics and Genomics

   Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

   Keva Li, Nicholas Tolman ... UK Biobank Eye and Vision Consortium

   Pyruvate and related metabolites are linked to reduced glaucoma risk among genetically predisposed individuals and mitigate disease in a mouse model, highlighting a potential metabolic mechanism of resilience.
3. 1. Cell Biology
   2. Immunology and Inflammation

   RAS–p110α signalling in macrophages is required for effective inflammatory response and resolution of inflammation

   Alejandro Rosell, Agata Adelajda Krygowska ... Esther Castellano Sanchez

   Disruption of RAS–p110α signalling in macrophages impairs both the initiation and resolution of inflammatory responses, revealing a critical regulatory role in immune function and inflammation control.
4. 1. Cell Biology

   Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells

   Affiong Ika Oqua, Kin Chao ... Alejandra Tomas

   Islet cholesterol levels determine GLP-1R function, with several cholesterol-binding sites mapped in active vs inactive receptors and one, containing Val229, shown to control GLP-1R behaviour in beta cell models.
5. 1. Cell Biology
   2. Neuroscience

   CO₂-dependent opening of Connexin 43 hemichannels

   Valentin-Mihai Dospinescu, Alexander Mascarenhas ... Nicholas Dale
6. 1. Cell Biology
   2. Cancer Biology

   A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer

   Saima Usman, W Andrew Yeudall ... Ahmad Waseem
7. 1. Cell Biology
   2. Cancer Biology

   RUNX2 Isoform II Protects Cancer Cells from Ferroptosis and Apoptosis by Promoting PRDX2 Expression in Oral Squamous Cell Carcinoma

   Junjun Huang, Rong Jia, Jihua Guo
8. 1. Cell Biology
   2. Cancer Biology

   DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma

   Simar Pal Singh, Michelle D van den Beukel ... Annemiek B van Spriel
9. 1. Cell Biology

   Emergence of Dip2-mediated Specific DAG-based PKC Signalling Axis in Eukaryotes

   Sakshi Shambhavi, Sudipta Mondal ... Rajan Sankaranarayanan
10. 1. Cancer Biology
    2. Cell Biology

    Breast Cancer: How cell crowding causes cancer cells to spread

    Rui Hua, Jean X Jiang

    Cell crowding causes high-grade breast cancer cells to become more invasive by activating a molecular switch that causes the cells to shrink and spread.