Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    SMC5/6-Mediated Plasmid Silencing is Directed by SIMC1-SLF2 and Antagonized by the SV40 Large T Antigen

    Martina Oravcová, Minghua Nie ... Michael N Boddy
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

    Devon E Mason, Paula Camacho ... Joel D Boerckel
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology

    Vesiculation pathways in clathrin-mediated endocytosis

    Xinran Wang, Julien Berro, Rui Ma
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Developmental Biology

    Glucose-stimulated KIF5B-driven microtubule sliding organizes microtubule networks in mouse pancreatic β cells

    Kai M Bracey, Margret A Fye ... Irina Kaverina
    Sub-membrane microtubule array, known to prevent excessive glucose-stimulated insulin secretion, depends on kinesin-1 KIF5B, which moves microtubules to both generate and remodel this array, potentially regulating the dosage of secretion.
    1. Cell Biology

    Distinct functions of cardiac β-adrenergic receptors in the T-tubule vs. outer surface membrane

    George WP Madders, Marion Barthé ... Rodolphe Fischmeister
    A size exclusion strategy using PEGylation of isoprenaline allowed to demonstrate that cardiac β-adrenergic receptors located in the outer surface membrane control mainly cAMP/PKA in the cytosol while those located in the T-tubule membrane control cAMP/PKA in the nucleus.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

    Takashi Hotta, Morgan L Pimm ... Kristen J Verhey
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology

    Abnormal shear stress induces ferroptosis in endothelial cells via KLF6 downregulation

    Jingang Cui, Zhiyu Fan ... Yongsheng Ding
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Cell Biology

    A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

    Tongtong Xu, Fujun Cao ... Chengjian Zhao
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Unbend: Correction of local beam-induced sample motion in cryo-EM images using a 3D spline model

    Lingli Kong, Ximena Zottig ... Nikolaus Grigorieff
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

    Roya Pournejati, Jessica M Huang ... Oscar Vivas
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
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Highlights

    1. Cell Biology
    2. Chromosomes and Gene Expression

    A crossroads in the aging process

    Kiyan Shabestary, Daniel E Gottschling
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. David Ron
    Cambridge University, United Kingdom
  4. See more editors