Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Genetically engineered mesenchymal stem cells as a nitric oxide reservoir for acute kidney injury therapy

    Haoyan Huang, Meng Qian ... Zongjin Li
    Engineered mesenchymal stem cells (MSCs) could produce mutant β-galactosidase and trigger nitric oxide (NO) release when the NO prodrug is systemically administered, which can achieve NO release in a precise spatiotemporal manner and augment the therapeutic efficiency of MSCs.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP

    Maria Körner, Susanne R Meyer ... Alexander Buchberger
    The previously uncharacterized, evolutionarily conserved FAM104 proteins VCF1/2 stimulate the nuclear import of p97/VCP, with their absence causing reduced nuclear p97/VCP levels, slow growth, and hypersensitivity to pharmacological inhibition of p97/VCP.
    1. Cell Biology
    2. Neuroscience

    Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans

    Elisabeth Jongsma, Anita Goyala ... Collin Yvès Ewald
    A novel Caenorhabditis elegans model that secretes human amyloid beta forms aggregates in the extracellular matrix, which are removed by activation of extracellular matrix dynamics.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus

    Vikrant K Bhosle, Chunxiang Sun ... Lisa A Robinson
    SLIT2, a prototypic neuro-repellent, spatiotemporally coordinates host defense against Staphylococcus aureus infection by priming neutrophils and stimulating release of reactive oxygen species and secondary and tertiary granules, potently enhancing bactericidal actions of neutrophils.
    1. Cell Biology
    2. Immunology and Inflammation

    Arpin deficiency increases actomyosin contractility and vascular permeability

    Armando Montoya-García, Idaira M. Guerrero-Fonseca ... Michael Schnoor
    1. Cell Biology
    2. Medicine

    Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

    Martin Wohlwend, Pirkka-Pekka Laurila ... Johan Auwerx

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. Erica Golemis
    Fox Chase Cancer Center, United States
  4. See more editors