Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Genetics and Genomics

    Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma

    Keva Li, Nicholas Tolman ... UK Biobank Eye and Vision Consortium
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Clearance of protein aggregates during cell division

    Shoukang Du, Yuhan Wang ... Ting Gang Chew
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Cell Biology

    C-terminal tagging, transmembrane domain hydrophobicity, and an ER retention motif influence the secretory trafficking of the inner nuclear membrane protein emerin

    Jessica Mella, Regan Volk ... Abigail Buchwalter
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cell Biology

    CDK-mediated phosphorylation of PNKP is required for end-processing of single-strand DNA gaps on Okazaki fragments and genome stability

    Kaima Tsukada, Rikiya Imamura ... Mikio Shimada
    It was revealed that phosphorylation of the DNA repair enzyme PNKP at threonine 118 by CDK is required for DNA replication through the gap filling of Okazaki fragments.
    1. Cell Biology
    2. Developmental Biology

    Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes

    Pavan K Nayak, Arul Subramanian, Thomas F Schilling
    1. Cell Biology

    MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migration

    Peipei Xu, Rui Zhang ... Wenxiang Meng
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Cell Biology
    2. Neuroscience

    The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke

    Tingbo Li, Ling Yang ... Jie-Min Jia
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Incomplete
    1. Cell Biology

    CILP from Cartilage Intermediate Zone Inhibits Hyaline Cartilage Fibrosis and Chondrocyte Ferroptosis via Keap1-Nrf2 Axis in Early Osteoarthritis Exercise Therapy

    Shuangshuo Jia, Zhehan Hu ... Yue Yang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease

    Vibhavari Aysha Bansal, Jia Min Tan ... Toh Hean Ch'ng
    Characterization of nuclear pore loss and dysfunction in nucleocytoplasmic compartmentalization in Alzheimer's disease neurons.
    1. Cell Biology

    Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex

    Jittoku Ihara, Yibin Huang ... Koichi Yamamoto
    Oxidized LDL synergizes with angiotensin II to amplify Gq signaling via the AT1-LOX1 receptor complex, revealing a novel mechanism driving renal dysfunction in hypertension and dyslipidemia.
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Highlights

    1. Cell Biology
    2. Developmental Biology

    Rethinking ovarian biology

    Yan Zhang, Hua Zhang
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    The Institute of Photonic Sciences, Spain
  3. Lynne-Marie Postovit
    University of Alberta, Canada
  4. See more editors