Cell Biology

Cell Biology

eLife publishes research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we publish and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1

    Meng Zhao, Niels Banhos Dannieskiold-Samsøe ... Katrin J Svensson
    1. Cell Biology
    2. Genetics and Genomics

    Resurrecting essential amino acid biosynthesis in mammalian cells

    Julie Trolle, Ross M McBee ... Harris H Wang
    1. Cell Biology
    2. Neuroscience

    Keratinocyte PIEZO1 modulates cutaneous mechanosensation

    Alexander R Mikesell, Olena Isaeva ... Cheryl L Stucky
    Epidermal PIEZO1 is a key keratinocyte mechanotransducer which mediates normal behavioral and sensory neuron responses to cutaneous mechanical stimulation.
    1. Cell Biology
    2. Developmental Biology

    Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration

    Audrey Miller Williams, Seth Donoughe ... Sally Horne-Badovinac
    1. Cell Biology

    PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells

    Gina M LoMastro, Chelsea G Drown ... Andrew Jon Holland
    Genetically engineered mouse models show that PLK4 protein and kinase activity are essential for multiciliogenesis, demonstrating that the early steps of centriole assembly are conserved between cycling and multiciliated cells.
    1. Cell Biology
    2. Genetics and Genomics

    The VINE complex is an endosomal VPS9-domain GEF and SNX-BAR coat

    Shawn P Shortill, Mia S Frier ... Elizabeth Conibear
    The yeast VARP homolog forms a new sorting nexin complex that promotes its own membrane recruitment through GEF activity and regulates the distribution of endosomal proteins.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Wolbachia action in the sperm produces developmentally deferred chromosome segregation defects during the Drosophila mid-blastula transition

    Brandt Warecki, Simon William Abraham Titen ... William Sullivan
    Differentiation of mitotic errors occurring during late embryonic development from the well-characterized first division defects provides new insight into the mechanisms of Wolbachia-induced cytoplasmic incompatibility.
    1. Cell Biology

    Centrioles: One master to rule them all

    Pablo Barbeito, Francesc R Garcia-Gonzalo
    Multiciliated cells rely on the same master regulator as dividing cells to amplify the number of centrioles needed to generate the hair-like structures that coat their cell surface.
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Senior editors

  1. Anna Akhmanova
    Utrecht University, Netherlands
  2. Marianne E Bronner
    Marianne E Bronner
    California Institute of Technology, United States
  3. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors