Cell Biology

Latest articles

1. 1. Cell Biology
   2. Developmental Biology

   Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila

   Hannah J Green et al.

   Integrin and actin associated proteins are resolved into four layers within myofibril attachments, an architecture requiring balanced positive and negative regulation of integrin adhesion with integrated mechanotransduction and actin pathways.
2. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration

   Aurore Lhonore et al.
3. 1. Cell Biology

   The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation

   Rengasayee Veeraraghavan et al.
4. 1. Cell Biology
   2. Developmental Biology

   Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos

   Matthew Richard Johnson et al.

   In early Drosophila embryos, histone H2Av continuously exchanges between cytoplasmic lipid droplets, a process that modulates H2Av import into nuclei and constitutes a novel post-translational strategy to regulate nuclear H2Av levels.
5. 1. Cell Biology

   Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans

   Nikolay Burnaevskiy et al.

   Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.
6. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Structural insights into the architecture and membrane interactions of the conserved COMMD proteins

   Michael D Healy et al.

   A structural basis for the assembly of core subunits of the Commander Complex has been discovered.
7. 1. Cell Biology

   Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

   Tae Yeon Yoo et al.

   Quantitative experiments and theory show that the tension-dependent regulation of NDC80 binding to kinetochore microtubules arises from a combination of the changing Aurora B concentration at NDC80 and the nonlinearity of Aurora B autoactivation.
8. 1. Cell Biology
   2. Developmental Biology

   Radially patterned cell behaviours during tube budding from an epithelium

   Yara E Sanchez-Corrales et al.

   Quantitative analysis in quasi-3D reveals apically driven cell behaviours that are closely coordinated across the tissue to allow ordered tube invagination through a focal point.
9. 1. Cell Biology
   2. Human Biology and Medicine

   Prolonged cross-bridge binding triggers muscle dysfunction in a fly model of myosin-based hypertrophic cardiomyopathy

   William A Kronert et al.
10. 1. Cell Biology

    Autophagy-dependent rRNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development

    Yubing Liu et al.