Cell Biology

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Genetically engineered mesenchymal stem cells as a nitric oxide reservoir for acute kidney injury therapy

   Haoyan Huang, Meng Qian ... Zongjin Li

   Engineered mesenchymal stem cells (MSCs) could produce mutant β-galactosidase and trigger nitric oxide (NO) release when the NO prodrug is systemically administered, which can achieve NO release in a precise spatiotemporal manner and augment the therapeutic efficiency of MSCs.
2. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP

   Maria Körner, Susanne R Meyer ... Alexander Buchberger

   The previously uncharacterized, evolutionarily conserved FAM104 proteins VCF1/2 stimulate the nuclear import of p97/VCP, with their absence causing reduced nuclear p97/VCP levels, slow growth, and hypersensitivity to pharmacological inhibition of p97/VCP.
3. 1. Cell Biology
   2. Neuroscience

   Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans

   Elisabeth Jongsma, Anita Goyala ... Collin Yvès Ewald

   A novel Caenorhabditis elegans model that secretes human amyloid beta forms aggregates in the extracellular matrix, which are removed by activation of extracellular matrix dynamics.
4. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   A lipid transfer protein knockout library reveals ORP9-ORP11 dimer mediating PS/PI(4)P exchange at the ER-trans Golgi contact site to promote sphingomyelin synthesis

   Birol Cabukusta, Shalom Borst Pauwels ... Jacques Neefjes
5. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission

   Elliott L Paine, Jack J Skalicky ... Wesley I Sundquist
6. 1. Cell Biology
   2. Microbiology and Infectious Disease

   The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus

   Vikrant K Bhosle, Chunxiang Sun ... Lisa A Robinson

   SLIT2, a prototypic neuro-repellent, spatiotemporally coordinates host defense against Staphylococcus aureus infection by priming neutrophils and stimulating release of reactive oxygen species and secondary and tertiary granules, potently enhancing bactericidal actions of neutrophils.
7. 1. Cell Biology
   2. Immunology and Inflammation

   Arpin deficiency increases actomyosin contractility and vascular permeability

   Armando Montoya-García, Idaira M. Guerrero-Fonseca ... Michael Schnoor
8. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

   Yin Luo, Huanmeng Hao ... Ding Xu
9. 1. Cell Biology
   2. Immunology and Inflammation

   ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin

   Cristina Cacho-Navas, Carmen López-Pujante ... Jaime Millán
10. 1. Cell Biology
    2. Medicine

    Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

    Martin Wohlwend, Pirkka-Pekka Laurila ... Johan Auwerx