Immunoglobulin concentration and cytokine expression in the gastrointestinal tract after RSP immunization and challenge with Salmonella.
Total IgA concentration in jejunum content (A), in colon content (B) and in feces (C). RSP-specific IgA titers in jejunum content (D), in colon content (E) and in feces (F). Il-1β (G), Il-6 (H) and Tnf-α (I) expression in colon mucosa. Open bars represent non-immunized (Non-Imm) mice; solid bars represent immunized (Imm) mice. Results are expressed as means ± SEMs (n= 10–12 animals). Means without a common letter differ, P<0.05. IgA, immunoglobulin A; IgG, immunoglobulin G; Il, interleukin; Int, interaction between both factors; Tnf-α, tumor necrosis factor alpha.