Microbiology and Infectious Disease

Latest articles

1. 1. Microbiology and Infectious Disease

   A novel decoy strategy for polymyxin resistance in Acinetobacter baumannii

   Jaeeun Park et al.

   Outer membrane vesicles serve as decoys to reduce the chance of direct polymyxin B (PMB) binding to cells, which partly explains why many clinical isolates and microbial communities can be protected against PMB treatment.
2. 1. Epidemiology and Global Health
   2. Microbiology and Infectious Disease

   Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

   Barbara H Stokes et al.

   Plasmodium falciparum K13 mutations confer resistance to the antimalarial artemisinin in Asian and African parasites, with most gene-edited mutant K13 African parasite lines showing a fitness cost that may predict slow dissemination of artemisinin resistance in high-transmission settings.
3. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci

   Joshua C D'Aeth et al.

   Selection by national-level antibiotic consumption and vaccination trends drives atypical recombinations, frequently resulting in interspecies sequence exchange at many sites across a bacterial species’ chromosome.
4. 1. Epidemiology and Global Health
   2. Microbiology and Infectious Disease

   Identification of drugs associated with reduced severity of COVID-19 – a case-control study in a large population

   Ariel Israel et al.

   Large-scale retrospective analysis suggests medications and dietary supplements, such as rosuvastatin, ezetimibe, ubiquinone, risedronate, vitamin D, and magnesium, are associated with a lower rate of severe COVID-19 disease.
5. 1. Epidemiology and Global Health
   2. Microbiology and Infectious Disease

   Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

   Nikhil Faulkner et al.
6. 1. Microbiology and Infectious Disease

   NirD curtails the stringent response by inhibiting RelA activity in Escherichia coli

   Loïc Léger et al.

   Genetic and biochemical approaches uncover a novel mode of regulation of the alarmone synthetase RelA through a functional and direct interaction with the small subunit of the nitrite reductase NirD.
7. 1. Microbiology and Infectious Disease

   KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia

   Rajnish Kumar Singh et al.

   KSHV nullifies hypoxic restriction of DNA replication.
8. 1. Microbiology and Infectious Disease

   Revisiting the guidelines for ending isolation for COVID-19 patients

   Yong Dam Jeong et al.

   Compared with the approach isolating COVID-19 patients for a fixed period, the approach using repeated PCR testing mitigates unnecessarily lengthy isolation of patients while minimizing the risk of further transmission.
9. 1. Microbiology and Infectious Disease

   Co-circulation of multiple influenza A reassortants in swine harboring genes from seasonal human and swine influenza viruses

   Pia Ryt-Hansen et al.
10. 1. Microbiology and Infectious Disease

    A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma

    Dayana C Farhat et al.

    The epitranscriptomic-driven mRNA polyadenylation pathway protects transcriptome integrity by restricting transcriptional read-throughs and RNA chimera formation in apicomplexan parasites and plants.