Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Phospholipid scramblase 1 (PLSCR1) regulates interferon-lambda receptor 1 (IFN-λR1) and IFN-λ signaling in influenza A virus (IAV) infection

    Alina Xiaoyu Yang, Lisa Ramos-Rodriguez ... Yang Zhou
    PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Enteropathogenic E. coli-mediated Fast and Coordinated Ca²⁺ responses regulate NF-κB activation

    Fangrui Guo, Roberto Ornelas Guevara ... Guy Tran Van Nhieu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

    Yoshitaka Tateishi, Yuriko Ozeki ... Sohkichi Matsumoto
    Transposon sequencing analyses reveal that among genomically diverse clinical Mycobacterium intracellulare strains and the type strain, 131 genes were comprehensively identified as universal essential genes suggesting promising drug targets.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural basis for collagen recognition by the Streptococcus pyogenes M3 protein and its involvement in biofilm

    Marta Wojnowska, Takeaki Wajima ... Ulrich Schwarz-Linek
    The T-shaped fold of an abundant surface protein ties streptococci to collagens, an interaction that enhances biofilm such as often found in invasive infections.
    1. Microbiology and Infectious Disease

    Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis

    Kamal L Nahas, Viv Connor ... Colin M Crump
    Deletion of specific herpes simplex virus proteins prevents the progression of virus assembly at discrete stages, allowing detailed 3D imaging of rare events in the morphogenesis of virus particles.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    The olfactory receptor SNIF-1 mediates foraging for leucine-rich diets in C. elegans

    Ritika Siddiqui, Nikita Mehta ... Varsha Singh
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    Membrane affinity difference between MinD monomer and dimer is not crucial for MinD gradient formation in Bacillus subtilis

    Laura C Bohorquez, Henrik Strahl ... Leendert W Hamoen
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Microbiology and Infectious Disease

    An in vitro human vessel model to study Neisseria meningitidis colonization and vascular damages

    Léa Pinon, Melanie Chabaud ... Guilllaume Dumenil
    A vessel on a chip microfluidic device recapitulates the main features of meningococcal vascular colonization, providing high time and space microscopy resolution of the infection process in 3D.
    1. Microbiology and Infectious Disease

    Niche exclusion of a lung pathogen in mice with designed probiotic communities

    Kelsey E Hern, Ashlee M Phillips ... Adam P Arkin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    The structural context of mutations in proteins predicts their effect on antibiotic resistance

    Anna G Green, Mahbuba Tasmin ... Maha R Farhat
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing

Senior editors

  1. Diane M Harper
    University of Michigan, United States
  2. Bavesh Kana
    University of the Witwatersrand, South Africa
  3. Joshua T Schiffer
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors