Microbiology and Infectious Disease

Latest articles

1. 1. Microbiology and Infectious Disease

   Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow

   Ilona P Foik, Summer J Kasallis ... Albert Siryaporn
2. 1. Microbiology and Infectious Disease

   A dual role for PGLYRP1 in host defense and immune regulation during B. pertussis infection

   David M Rickert, Sasha Cardozo ... Ciaran Skerry

   Bordetella pertussis hijacks the host innate immune protein PGLYRP1 via tracheal cytotoxin to suppress inflammation and evade killing, revealing a novel immune evasion strategy.
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Functional Convergence of Genetically Diverse B-Cell Receptors in Simian-HIV Infected Rhesus Macaques

   Shengli Song, Hui Li ... Garnett Kelsoe
4. 1. Microbiology and Infectious Disease

   Pathogen-phage geomapping to overcome resistance

   Camilla Do, Keiko Christine Salazar ... Anthony W Maresso

   Targeted ecological sampling combined with a portable enrichment device rapidly yields a diverse array of bacteriophages against drug-resistant pathogens.
5. 1. Microbiology and Infectious Disease

   Nanoscopy reveals heparan sulfate clusters as docking sites for SARS-CoV-2 attachment and entry

   Sue Han, Xin Wang ... Ling-Gang Wu

   Cell-surface heparan sulfate clusters, not the generally assumed ACE2, mediate SARS-CoV-2 attachment and endocytic entry, fundamentally revising the viral entry paradigm and establishing heparan sulfate as a primary therapeutic target.
6. 1. Microbiology and Infectious Disease

   High-throughput quantification of population dynamics using luminescence

   Malte Muetter, Daniel C Angst ... Sebastian Bonhoeffer

   Tracking luminescent reporter light intensity is a fast, easy way to quantify population decline at high concentrations and tends to be a better proxy for biomass than for cell number.
7. 1. Microbiology and Infectious Disease

   Apparent cooperativity between human CMV virions introduces errors in conventional methods of calculating multiplicity of infection

   Christopher Peterson, Joshua Miller ... Vitaly V Ganusov

   Cooperation between individual virions of human cytomegalovirus at infecting cells leads to nonlinear scaling of cell infection probability with virion concentration.
8. 1. Microbiology and Infectious Disease

   Niche exclusion of a lung pathogen in mice with designed probiotic communities

   Kelsey E Hern, Ashlee M Phillips ... Adam P Arkin

   Probiotic communities designed to inhibit a lung pathogen through niche exclusion show promise as a novel method of preventing respiratory infection.
9. 1. Microbiology and Infectious Disease

   Multidimensional in vitro assay for antimalarial combination testing and pharmacodynamic modeling – the MULT-i² assay

   Angela Hellingman, Christin Gumpp ... Matthias Rottmann
10. 1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection

    Kely Catarine Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli

    TNF-driven metabolic reprogramming enhances glucose utilization in monocytes through inducible nitric oxide synthase (iNOS) and hypoxia-inducible factor 1α (HIF-1α), promoting parasite control and host resistance during Plasmodium infection.