Microbiology and Infectious Disease

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity

   CJ Cambier et al.
2. 1. Microbiology and Infectious Disease

   Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis

   Jennifer L Elliott et al.

   HIV-1 integrase-RNA interactions account for the key role of integrase in particle maturation.
3. 1. Microbiology and Infectious Disease

   Viral Maturation: How to package the RNA of HIV-1

   Alex Kleinpeter, Eric O Freed

   Interactions between viral RNA and the integrase enzyme are required for HIV-1 particles to become infectious, a process that can be disrupted through multiple mechanisms.
4. 1. Microbiology and Infectious Disease

   Doxycycline has distinct apicoplast-specific mechanisms of antimalarial activity

   Megan Okada et al.

   Doxycycline used at a slightly higher concentration kills Plasmodium falciparum malaria parasites with faster, first-cycle activity through a novel organelle-specific mechanism.
5. 1. Microbiology and Infectious Disease

   Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes

   Shuxin Liu et al.

   A novel bacterial deubiquitinase with multiple chain types specificity regulates the association of ubiquitinated proteins on the phagosome of Legionella pneumophila.
6. 1. Microbiology and Infectious Disease
   2. Structural Biology and Molecular Biophysics

   Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict

   James B Eaglesham et al.
7. 1. Microbiology and Infectious Disease

   The alternative sigma factor σ^X mediates competence shut-off at the cell pole in Streptococcus pneumoniae

   Calum HG Johnston et al.

   Tracking fluorescent fusion proteins in competent pneumococcal cells reveals a polar hub for competence regulation, with the alternative sigma factor σX relocalizing DprA to this hub to mediate competence shut-off.
8. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Transcription termination and antitermination of bacterial CRISPR arrays

   Anne M Stringer et al.

   Many bacteria use the Nus factor antitermination complex to prevent premature Rho-dependent transcription termination of their CRISPR arrays.
9. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   A motogenic GABAergic system of mononuclear phagocytes facilitates dissemination of coccidian parasites

   Amol K Bhandage et al.
10. 1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Asynchrony between virus diversity and antibody selection limits influenza virus evolution

    Dylan H Morris et al.