Microbiology and Infectious Disease

Latest articles

1. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Extensive transmission of microbes along the gastrointestinal tract

   Thomas SB Schmidt et al.

   Microbial populations are continuous along the gastrointestinal tract, with increased transmission in colorectal cancer and rheumatoid arthritis patients.
2. 1. Microbiology and Infectious Disease

   Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

   Eva S Istvan et al.

   The malaria parasite Niemann-Pick Type C1-related protein is an important new antimalarial target.
3. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Microbiome: Does disease start in the mouth, the gut or both?

   Andrei Prodan et al.

   Oral bacteria colonize the gut more frequently than previously thought.
4. 1. Microbiology and Infectious Disease

   Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses

   Efraín E Rivera-Serrano et al.

   Quasi-enveloped hepatitis A virions undergo clathrin-mediated endocytosis, followed by ALIX-dependent trafficking to lysosomes where the quasi-envelope is degraded, triggering uncoating of the RNA genome in association with lysosomal membrane rupture.
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Connexin-43-dependent ATP release mediates macrophage activation during sepsis

   Michel Dosch et al.

   Autocrine activation of macrophages is modulated by Connexin-43-mediated ATP release in response to TLR-4 and -2 agonists in a P2Y1-dependent manner, ultimately determining sepsis survival.
6. 1. Microbiology and Infectious Disease

   A multicellular way of life for a multipartite virus

   Anne Sicard et al.

   A multipartite virus functionally spreads its distinct genome segments in distinct individual cells of the host plant, and complementation of the viral genes across cells allows a pluricellular infection cycle.
7. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Functional proteomic atlas of HIV infection in primary human CD4+ T cells

   Adi Naamati et al.

   Identification and characterisation of proteins and processes regulated by HIV in primary human CD4+ T cells using an HIV reporter virus for one-step, antibody-free magnetic selection.
8. 1. Cell Biology
   2. Microbiology and Infectious Disease

   HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the nuclear pore complex

   David Alejandro Bejarano et al.

   Interaction of HIV capsids with the cellular protein cleavage-and-polyadenylation factor 6 at the inner side of nuclear pores promotes nuclear entry of the viral replication complex in primary human macrophages.
9. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Immunology: Identifying a nuclear passport for HIV

   Lorena Zuliani-Alvarez, Greg J Towers

   Identification of a protein that pulls HIV into the nucleus explains a key step in HIV infection.
10. 1. Cell Biology
    2. Microbiology and Infectious Disease

    Basalin is an evolutionarily unconstrained protein revealed via a conserved role in flagellum basal plate function

    Samuel Dean et al.

    Basalins are intrinsically disordered proteins with astonishingly high-sequence divergence that are essential for building the transition zone basal plate and for proper central pair nucleation.