Microbiology and Infectious Disease

Latest articles

1. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off

   Sarah E Dremel, Neal A DeLuca

   Herpes simplex ICP4 preferentially binds to and delineates the viral genome, ultimately resulting in robust viral transcription at the expense of the host.
2. 1. Microbiology and Infectious Disease

   Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with UTIs

   Anna Sintsova et al.

   Conserved transcriptomic profile of uropathogenic E. coli in patients identifies an infection-specific metabolic state.
3. 1. Microbiology and Infectious Disease

   A single regulator NrtR controls bacterial NAD⁺ homeostasis via its acetylation

   Rongsui Gao et al.

   Functional definition of NrtR and the discovery of its acetylation represents a first paradigm for linking protein acetylation to bacterial central NAD⁺ metabolism.
4. 1. Microbiology and Infectious Disease

   Sexual transmission of murine papillomavirus (MmuPV1) in Mus musculus

   Megan E Spurgeon, Paul F Lambert

   MmuPV1, a papillomavirus that infects laboratory mice (Mus musculus), is discovered to be sexually transmitted, providing a new animal virus model to study sexually transmitted human papillomaviruses (HPVs).
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements

   Michel Tassetto et al.

   Virus infection in mosquitoes initiates a highly discriminatory process in which fragments of viral RNA are reverse transcribed to create DNA copies that serve as templates of small antiviral RNAs.
6. 1. Developmental Biology
   2. Microbiology and Infectious Disease

   Cytoplasmic retention and degradation of a mitotic inducer enable plant infection by a pathogenic fungus

   Paola Bardetti et al.
7. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Bacterial survival in microscopic surface wetness

   Maor Grinberg et al.
8. 1. Human Biology and Medicine
   2. Microbiology and Infectious Disease

   Rare missense variants in the human cytosolic antibody receptor preserve antiviral function

   Jingwei Zeng et al.

   Studying the impact of natural variation on a key immune gene highlights how focusing on a single wild-type sequence overlooks that rare variants cause the most disease.
9. 1. Microbiology and Infectious Disease

   Transcriptome dynamics of the Myxococcus xanthus multicellular developmental program

   José Muñoz-Dorado et al.

   Investigation of global gene expression profiles during formation of the Myxococcus xanthus specialized biofilm reveals a genetic regulatory network that coordinates cell motility, differentiation, and secondary metabolite production.
10. 1. Microbiology and Infectious Disease

    Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii

    Alex Hunt et al.

    Partially overlapping functions of a limited subset of actin binding proteins allow the parasite Toxoplasma gondii to achieve actin regulation required for complex cellular processes.