Microbiology and Infectious Disease

Latest articles

1. 1. Microbiology and Infectious Disease

   MARCH8 inhibits viral infection by two different mechanisms

   Yanzhao Zhang et al.

   The host transmembrane protein MARCH8, previously known as an expression regulator of host proteins, is a powerful antiviral host factor with a potentially broad antiviral spectrum through two different mechanisms.
2. 1. Evolutionary Biology
   2. Microbiology and Infectious Disease

   A large effective population size for established within-host influenza virus infection

   Casper K Lumby et al.
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING

   Sytse J Piersma et al.

   Cytomegaloviruses are recognized by distinct sensors depending on the infected cell type and together these sensors are essential for viral control and downstream immune responses.
4. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

   Ali Alghamdi et al.
5. 1. Microbiology and Infectious Disease

   HetL, HetR and PatS form a reaction-diffusion system to control pattern formation in the cyanobacterium Nostoc PCC 7120

   Xiaomei Xu et al.
6. 1. Human Biology and Medicine
   2. Microbiology and Infectious Disease

   Augmented curation of clinical notes from a massive EHR system reveals symptoms of impending COVID-19 diagnosis

   Tyler Wagner et al.

   Applying deep learning technology for the large-scale curation of symptoms from unstructured EHR clinical notes accurately predicts the differential signals of COVID-19 diagnosis over the week preceding typical PCR testing.
7. 1. Microbiology and Infectious Disease

   Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides

   Giancarlo Noe Bruni, Joel M Kralj

   Aminoglycosides are a class of antibiotics that can kill Escherichia coli by building up internal voltage through disrupting the normal consumption of ATP.
8. 1. Microbiology and Infectious Disease

   Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity

   Yingying Fu et al.

   Cutaneous papillomaviruses potentially escape humoral immune response by synthesizing an alternative major capsid protein isoform during the initial course of infection that is unable to induce neutralizing antibodies.
9. 1. Microbiology and Infectious Disease

   Host sirtuin 2 as an immunotherapeutic target against tuberculosis

   Ashima Bhaskar et al.

   The inhibition of host Sirtuin-2 by AGK2 restricts mycobacterial growth in vivo by modulation of host transcriptome leading to activation of protective immune responses.
10. 1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Chronic ethanol consumption compromises neutrophil function in acute pulmonary Aspergillus fumigatus infection

    Nathalia Luisa Sousa de Oliveira Malacco et al.

    Cell biology analysis demonstrated for the first time the effect of chronic ethanol consumption in neutrophil impaired migration by CXCR2 downregulation and neutrophil function during acute Aspergillus fumigatus infection.