Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Microbiology and Infectious Disease

    The cow udder is a potential coinfection site for influenza A viruses

    Rute Maria Pinto, Colin P Sharp ... Paul Digard
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Microbiology and Infectious Disease

    Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis

    Nikol Kadeřábková, R Christopher D Furniss ... Despoina AI Mavridou
    Targeting disulfide bond formation disables multiple antibiotic resistance mechanisms and prevents cross-protection between pathogens associated with cystic fibrosis lung infections, restoring antibiotic efficacy in polymicrobial settings.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Screening the MMV Pathogen Box reveals the mitochondrial bc1-complex as a drug target in mature Toxoplasma gondii bradyzoites

    Deborah Maus, Elyzana Putrianti ... Martin Blume
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    In vitro sexual dimorphism establishment in schistosomes

    Remi Pichon, Magda E Lotkowska ... Gabriel Rinaldi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

    Wang Xu, Narendra Kumar Gonepudi ... Maolin Lu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Mitochondrial protein FgDML1 impacts DON toxin biosynthesis and cyazofamid sensitivity in Fusarium graminearum by affecting mitochondrial homeostasis

    Chenguang Wang, Xuewei Mao ... Yiping Hou
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Membrane Binding Controls the ATPase Cycle and Localization of MinD in Bacillus subtilis

    Helge Feddersen, Charlotte Dyckmanns, Marc Bramkamp
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa

    Jiadai Huang, Yue Sun ... Xin Deng
    Systematic ChIP-seq profiling of 172 transcription factors in Pseudomonas aeruginosa reveals a hierarchical regulatory architecture governing virulence and establishes a searchable database to guide antimicrobial drug discovery.
    1. Microbiology and Infectious Disease

    Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite development

    Pascale Pescher, Thibaut Douché ... Gerald F Späth
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Epigenetics and chromatin structure regulate var2csa expression and the placental-binding phenotype in Plasmodium falciparum

    Todd Lenz, Madle Sirel ... Ulf Ribacke
    Placenta-binding parasites show that chromatin-based mechanisms regulate placental malaria virulence gene, var2csa, and requires loss of H3K9me3-mediated heterochromatic silencing and 3D nuclear repositioning away from telomeric-repressive clusters.
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Highlights

    1. Microbiology and Infectious Disease

    Gut Microbiome: Bacteria weigh up costs and benefits of mobile weapons

    Zhao Wang, Yang Fu
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease
    3. Medicine

    Focus Issue: Trained Immunity

    Edited by Satyajit Rath et al.
    1. Microbiology and Infectious Disease

    Tuberculosis: A surprising new hiding place for a dangerous pathogen

    Sheetal Gandotra, Yogendra Singh

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Diane M Harper
    University of Michigan, United States
  3. Joshua T Schiffer
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors