Microbiology and Infectious Disease

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Respiro-Fermentation: To breathe or not to breathe?

   Lauren C Radlinski, Andreas J Bäumler

   Listeria monocytogenes uses respiration to sustain a risky fermentative lifestyle during infection.
2. 1. Microbiology and Infectious Disease

   WhyD tailors surface polymers to prevent premature bacteriolysis and direct cell elongation in Streptococcus pneumoniae

   Josué Flores-Kim et al.
3. 1. Evolutionary Biology
   2. Microbiology and Infectious Disease

   Functional and structural segregation of overlapping helices in HIV-1

   Maliheh Safari et al.

   The HIV proteins Env and Rev encode helices that overlap in the viral genome but alternate in functional importance so that the non-functional surface of one helix encodes the functional surface of the other.
4. 1. Microbiology and Infectious Disease

   Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense

   Kelsey Michelle Wells et al.

   Brucella facilitates its intracellular parasitism by hijacking the host-regulated IRE1α-dependent decay (RIDD)-BLOS1 innate immune defense system through the disassembly of the BLOC-1-related complex that results in the perinuclear trafficking of Brucella-containing vacuoles and enhanced susceptibility to infection.
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies

   Ceri Alan Fielding et al.
6. 1. Microbiology and Infectious Disease

   A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates

   Philip W Fowler et al.
7. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females

   Bretta Hixson et al.

   RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.
8. 1. Microbiology and Infectious Disease

   Typhoid toxin sorting and exocytic transport from Salmonella Typhi infected cells

   Shu-Jung Chang et al.
9. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid genome diversification

   Gabriel Machado Matos et al.

   Unique mechanisms of genetic exchange in the important protozoan pathogen Trypanosome cruzi were characterized in detail using genome analyses of hybrid clones at different time points, showing initial tetraploids followed by genome erosion.
10. 1. Microbiology and Infectious Disease

    Pervasive translation in Mycobacterium tuberculosis

    Carol Smith et al.

    Thousands of novel open-reading frames (ORFs) are translated in the bacterium Mycobacterium tuberculosis, including many short ORFs that are likely to contribute to cell fitness.