Microbiology and Infectious Disease

Latest articles

1. 1. Epidemiology and Global Health
   2. Microbiology and Infectious Disease

   Transmission dynamics and control of multidrug-resistant Klebsiella pneumoniae in neonates in a developing country

   Thomas Crellen et al.

   Colonisation with resistant Klebsiella pneumoniae in a Cambodian neonatal unit is driven by person-to-person transmission, transmissibility varies by sequence type, and antibiotic consumption generally increases the risk of acquisition.
2. 1. Microbiology and Infectious Disease

   Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state

   Miri Shnayder et al.
3. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Cryo electron tomography with volta phase plate reveals novel structural foundations of the 96-nm axonemal repeat in the pathogen Trypanosoma brucei

   Simon Imhof et al.

   Cryo electron tomography provides the first high-resolution 3D axoneme structure from any pathogenic organism, revealing novel structures that support the unique motility of these pathogens through host tissues.
4. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses

   Joshua R Kane et al.

   A peptide derived from BK and JC polyomavirus protein VP2/3 inhibits viral infection by targeting a binding site in the pore of polyomavirus VP1 pentamers, enabling future VP1-targeted therapeutic strategies.
5. 1. Microbiology and Infectious Disease

   Coordination of humoral immune factors dictates compatibility between Schistosoma mansoni and Biomphalaria glabrata

   Hongyu Li et al.

   A coordinated humoral immune response that includes recognition, effector and cytotoxic factors engages the cell-mediated immune response to defend a snail against infection by schistosome parasites.
6. 1. Microbiology and Infectious Disease

   Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase

   Tobias Geiger et al.
7. 1. Microbiology and Infectious Disease

   Dynamic post-translational modification profiling of M. tuberculosis-infected primary macrophages

   Jonathan M Budzik et al.
8. 1. Microbiology and Infectious Disease

   Transcriptomics: Revisiting the genomes of herpesviruses

   Bhupesh K Prusty, Adam W Whisnant

   Combining integrative genomics and systems biology approaches has revealed new and conserved features in the genome of human herpesvirus 6.
9. 1. Microbiology and Infectious Disease

   Comprehensive annotations of human herpesvirus 6A and 6B genomes reveal novel and conserved genomic features

   Yaara Finkel et al.

   Unbiased mapping of viral open reading frames (ORFs) and transcripts in HHV-6 genomes uncovers novel ORFs and lncRNAs that are conserved across betaherpesviruses.
10. 1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions

    Luis V Nobre et al.

    The human cytomegalovirus (HCMV) interactome systematically characterises high-confidence viral-viral and viral-host protein interactions in HCMV-infected cells, facilitating multiple novel insights into HCMV and herpesviral function.