Microbiology and Infectious Disease

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing

   Carlos Gorbea et al.
2. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   The Photorhabdus asymbiotica virulence cassettes deliver protein effectors directly into target eukaryotic cells

   Isabella Vlisidou et al.

   The insect pathogenic bacterium Photorhabdus has evolved astonishing nano-scale analogues of hypodermic syringes that it uses to inject toxins into host cells.
3. 1. Microbiology and Infectious Disease

   Bacterial Protein Secretion: Looking inside an injection system

   Sophie A Howard, Alain Filloux

   The proteins injected by bacteria into eukaryotic organisms can lead to fates as diverse as death and metamorphosis.
4. 1. Microbiology and Infectious Disease
   2. Structural Biology and Molecular Biophysics

   A contractile injection system stimulates tubeworm metamorphosis by translocating a proteinaceous effector

   Charles F Ericson et al.

   Bacteria produce a syringe-like structure, loaded with a single protein within the lumen of its needle-like tube, that is sufficient for stimulating animal metamorphosis.
5. 1. Microbiology and Infectious Disease

   The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins

   Ashley M Ngo et al.
6. 1. Evolutionary Biology
   2. Microbiology and Infectious Disease

   Evolutionary pathways to antibiotic resistance are dependent upon environmental structure and bacterial lifestyle

   Alfonso Santos-Lopez et al.
7. 1. Microbiology and Infectious Disease

   Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

   Myra Hosmillo et al.

   A key cellular stress granule protein, G3BP1, is critical for efficient norovirus infection, representing the first pan-norovirus, pro-viral factor identified to date.
8. 1. Microbiology and Infectious Disease

   Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

   Kevin J Forsberg et al.

   A high-throughput, activity-based selection identifies many phage-derived inhibitors of Cas9 from human fecal and oral metagenomes, with at least one inhibitor acting via a novel mechanism.
9. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Consistent and correctable bias in metagenomic sequencing experiments

   Michael R McLaren et al.

   A mathematical model of bias in marker-gene and metagenomic sequencing measurements explains systematic errors in defined mixtures of microbial species, and enables quantitative and reproducible investigation of biological communities.
10. 1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Apicomplexan-like parasites are polyphyletic and widely but selectively dependent on cryptic plastid organelles

    Jan Janouškovec et al.

    Apicomplexan-like parasites originated several times independently and many of them contain cryptic plastid organelles, which demonstrate that the parasites evolved from photosynthetic algae.