Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Ecology
    2. Microbiology and Infectious Disease

    Novel class IIb microcins show activity against Gram-negative ESKAPE and plant pathogens

    Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
    12 new class IIb microcins have been structurally identified, phylogenetically assessed, and functionally tested for their antimicrobial activity, increasing the total number of these bacteriocins to 17.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis

    Amanda Mixon Blackwell, Yasaman Jami-Alahmadi ... Paul A Sigala
    Plasmodium parasites have repurposed the heme oxygenase scaffold from its canonical heme-degrading function to fulfill an essential and adaptive role in gene expression within the apicoplast organelle.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Lipid discovery enabled by sequence statistics and machine learning

    Priya M Christensen, Jonathan Martin ... Kelli L Palmer
    A previously unknown lipid modification by a bacterial antibiotic resistance enzyme was identified through the analysis of a family of antibiotic resistance enzyme sequences with a machine learning approach.
    1. Microbiology and Infectious Disease

    Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens

    Francesca Torelli, Diogo M da Fonseca ... Moritz Treeck
    Secreted effector proteins of Toxoplasma gondii parasites create a supportive immune environment in mice, allowing individually less fit mutants to thrive and evade detection by in vivo CRISPR screens.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

    Marisa S Egan, Emily A O’Rourke ... Sunny Shin
    Revised
    Reviewed Preprint v2
    Updated
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

    Zeinab M Chahine, Mohit Gupta ... Karine G Le Roch
    The PfMORC protein is proven to play a crucial role in chromatin structure, gene regulation and heterochromatin stability, categorizing PfMORC as a strong potential candidate for novel therapeutic interventions.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    β-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall

    Clara Bekirian, Isabel Valsecchi ... Thierry Fontaine
    β-1,6-Glucan is crucial for Candida albicans cell wall structure and integrity, adapting dynamically to environmental stresses and compensating for mannan deficiencies in cell wall organization.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A conserved cell-pole determinant organizes proper polar flagellum formation

    Erick E Arroyo-Pérez, John C Hook ... Simon Ringgaard
    FipA is a novel component required for bacteria that rely on FlhF/FlhG to properly localize their flagella to the cell pole.

Senior editors

  1. Diane M Harper
    University of Michigan, United States
  2. Bavesh Kana
    University of the Witwatersrand, South Africa
  3. John W Schoggins
    University of Texas Southwestern Medical Center, United States
  4. See more editors