Microbiology and Infectious Disease

Microbiology and Infectious Disease

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Latest articles

    1. Microbiology and Infectious Disease

    Heavy isotope labeling and mass spectrometry reveal unexpected remodeling of bacterial cell wall expansion in response to drugs

    Heiner Atze et al.
    Labeling with 13C and 15N in the absence of metabolic engineering enabled the exploration of peptidoglycan metabolism at a very fine level of detail based on kinetic characterization of isotopologues predicted to occur according to known recycling and biosynthesis pathways.
    1. Microbiology and Infectious Disease

    High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy

    Claudia A Vera-Arias et al.
    A novel high-throughput method for Plasmodium falciparum genotyping will enable malaria control programs to make informed decisions about the best tool to use for the diagnosis of malaria.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies

    Ceri Alan Fielding et al.
    SARS-CoV-2 host-shutoff inhibits innate NK surveillance by suppressing activating ligands, however ADCC provides a potent NK stimulus that is mediated by antibodies targeting Nucleocapsid, ORF3a, and Membrane, with those targeting Spike being significantly weaker.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Natural Killer Cells: Taking on SARS-CoV-2

    Paola Kučan Brlić, Ilija Brizić
    A new study sheds light on how SARS-CoV-2 influences the way natural killer cells can recognize and kill infected cells.
    Insight
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat

    Mengyao Wang et al.
    The Toll-like receptor 2-4 genetic modification goat improves effectively resistance against Staphylococcus aureus infection by enhancing autophagy level, and it provides a novel strategy for challenge of S. aureus-caused infections.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts

    Carlos-Henrique D Barbosa et al.
    Cytotoxic CD4 T lymphocytes are abundantly generated in T. cruzi-infected mice, predominantly infiltrate infected hearts, depend on T-cell intrinsic IL-18R/MyD88 signaling for expansion and their blood frequency correlates with the severity of chronic myocarditis in patients with Chagas disease.
    1. Microbiology and Infectious Disease

    Metabolic basis for the evolution of a common pathogenic Pseudomonas aeruginosa variant

    Dallas L Mould et al.
    Microbial variants that arise during chronic lung infections have an increased ability to use nutrients that are abundant in lung infections.

Senior editors

  1. Miles P Davenport
    University of New South Wales, Australia
  2. Neil Ferguson
    Imperial College London, United Kingdom
  3. Dominique Soldati-Favre
    University of Geneva, Switzerland
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