Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Microbiology and Infectious Disease

    Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein

    Qibin Geng, Yushun Wan ... Fang Li
    Lys417 regulates the opening and closing of SARS-CoV-2 spike protein, allowing SARS-CoV-2 to maintain a delicate balance between infectiousness and evading host immune response.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance

    Rebecca EK Mandt, Madeline R Luth ... Amanda K Lukens
    The mutational flexibility of the antimalarial target dihydroorotate dehydrogenase thwarts the use of collateral sensitivity as a strategy to suppress the evolution of resistance.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Indole produced during dysbiosis mediates host–microorganism chemical communication

    Rui-Qiu Yang, Yong-Hong Chen ... Cheng-Gang Zou
    In C. elegans, neuronic TRPA-1 senses bacterial accumulation by detecting indole production to up-regulate lysozyme genes via FOXO/DAF-16 in the intestine, thereby delaying microbial dysbiosis.

Senior editors

  1. Miles P Davenport
    University of New South Wales, Australia
  2. Neil Ferguson
    Imperial College London, United Kingdom
  3. Bavesh Kana
    University of the Witwatersrand, South Africa
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