The absence of generally assumed strong correlations between striatal dopamine synthesis capacity and simple indices of working memory capacity, trait impulsivity, and spontaneous eye-blink rate warrants caution for using these traits as proxy measures to replace direct striatal dopamine assessments.

Metabotropic glutamate receptors modulate impulse control by the subthalamic nucleus, dissociating trait impulsivity from basal ganglia motor function.

A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.

Greed personality trait is associated with behavioral loss aversion via the mediation of the neural loss aversion signal in the medial orbitofrontal cortex.

The findings have a major impact in understanding the different reward systems involved in two types of addictive behavior, and these advances have implications for prevention and treatment.

In adolescent rats, whose actions are more impulsive, neuronal striatal activity that precedes self-initiated action sequences has a steeper modulation by waiting time compared to the modulation found in adults.

The human substantia nigra can be parcellated into three subdivisions that subserve emotional, cognitive and somatomotor function.

Improvement in levels of anxious-depression corresponds with increased confidence in performance among individuals receiving mental health treatment within a large longitudinal dataset.

A selective reuptake inhibitor shows a beneficial effect in healthy humans during an effort-benefit tradeoff task, mediated at the computational level by a specific alleviation of effort cost.