19 results found
    1. Neuroscience

    Anatomical and functional organization of the human substantia nigra and its connections

    Yu Zhang et al.
    The human substantia nigra can be parcellated into three subdivisions that subserve emotional, cognitive and somatomotor function.
    1. Neuroscience

    Decreased brain connectivity in smoking contrasts with increased connectivity in drinking

    Wei Cheng et al.
    The findings have a major impact in understanding the different reward systems involved in two types of addictive behavior, and these advances have implications for prevention and treatment.
    1. Neuroscience

    Catecholaminergic challenge uncovers distinct Pavlovian and instrumental mechanisms of motivated (in)action

    Jennifer C Swart et al.
    Motivational coupling of action to reward and inhibition to punishment is subserved by dissociable learning and choice processes, and is modulated by dopamine/noradrenaline transporter blockade.
    1. Neuroscience

    Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium

    Stephanie C Gantz et al.
    The loss of calcium-dependent D2 autoreceptor desensitization caused by prior in vivo cocaine exposure may be conferred by an unexpected role of the D2L splice variant as an autoreceptor.
    1. Human Biology and Medicine
    2. Neuroscience

    Characterizing a psychiatric symptom dimension related to deficits in goal-directed control

    Claire M Gillan et al.
    A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.
    1. Neuroscience

    Neural mechanisms of economic commitment in the human medial prefrontal cortex

    Konstantinos Tsetsos et al.
    A striking dissociation exists in the medial prefrontal cortex, with different brain regions responding to value when commitments are deferred to the future and when prospects are judged to be undesirable.
    1. Neuroscience

    Sleep deprivation suppresses aggression in Drosophila

    Matthew S Kayser et al.
    A single night of sleep deprivation suppresses fighting behaviors in male fruit flies, with consequent impairments in reproductive fitness.
    1. Neuroscience

    A causal role for right temporo-parietal junction in signaling moral conflict

    Ignacio Obeso et al.
    Disrupting the right temporo-parietal junction did not change the general motivation to give or adapt behavior to social reputation cues, but specifically reduced the impact of moral-material conflict.
    1. Neuroscience

    Value generalization in human avoidance learning

    Agnes Norbury et al.
    Individual differences in generalization of aversive value (but not safety information) during human active avoidance learning specifically predict experience of anxiety and intrusive thoughts.
    1. Neuroscience

    The rate of transient beta frequency events predicts behavior across tasks and species

    Hyeyoung Shin et al.
    Across species, tasks and recording modalities, the rate of transient neocortical beta frequency (15-29Hz) events strongly predicts perceptual ability, providing fundamental mechanistic insight, with implications for tracking and manipulating brain dynamics.

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