Summation of metabotropic GABAergic responses remain linear even if most superficial layer interneurons specialized to recruit GABA_B receptors are simultaneously active.

In vivo genetic lineage-tracing reveals the developmental trajectory of neurogliaform cells, the main effectors of a powerful inhibitory motif in the neocortex.

Similar to their mouse counterparts, human neurogliaform cells that comprise a specialized from of inhibitory neuron, possess the ability to modulate their intrinsic excitability in response to ongoing network activity.

NMDA receptors mediate prominent supralinear summation of clustered excitatory inputs to the dendrites of neurogliaform and oriens-lacunosum moleculare interneurons of the hippocampus, showing that these cells perform sub-cellular computations.

Fast-spiking parvalbumin-expressing interneurons generate slow spillover-mediated GABAergic transmission to young adult-born and neighboring mature neurons of the dentate gyrus.

Id2 GABAergic interneurons represent a fourth major group of local inhibitory neurons that includes neurogliaform cells, and these neurons can be targeted using intersectional genetics, revealing their distinctive connectivity and in vivo activity properties.

An intersectional genetic vector approach allows the identification and characterization of novel hippocampal inhibitory neurons with both broad local connectivity within CA1 and long-range projections to several extrahippocampal areas.

Spontaneous theta oscillations and interneuron-specific phase preferences emerge spontaneously in a full-scale model of the isolated hippocampal CA1 subfield, corroborating and extending recent experimental findings.

In vivo whole-cell recordings in the piriform cortex show that two classes of layer 1 interneurons respond differently to odors, suggesting that these neurons provide kinetically distinctive types of odor-evoked feedforward inhibition.

A combined rehabitative protocol after stroke in the mouse normalizes transcallosal inhibition and promotes "true recovery" of forelimb motor function.