Browse our latest Neuroscience articles

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    1. Neuroscience

    Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep

    Elise J Meijer, Marissa Mueller ... Zoltán Molnár
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Resolving synaptic events using subsynaptically targeted GCaMP8 variants

    Jiawen Chen, Junhao Lin ... Dion Dickman
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Age-dependent predictors of effective reinforcement motor learning across childhood

    Nayo M Hill, Haley M Tripp ... Amy J Bastian
    Reinforcement motor learning of probabilistic tasks shows a protracted developmental trajectory in childhood due to high motor noise and low exploration, though performance deficits can be ameliorated in younger children by reducing task demands in spatial processing and probabilistic reasoning.
    1. Neuroscience

    Orexin population activity precisely reflects net body movement across behavioral and metabolic states

    Alexander L Tesmer, Paulius Viskaitis ... Denis Burdakov
    Orexin neurons precisely track body movement across behavioral and metabolic states, revealing a neural mechanism that links motor activity to arousal and energy resources.
    1. Neuroscience

    DeePosit, an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments

    David Peles, Shai Netser ... Shlomo Wagner
    Thermal imaging, computer vision tools, and an open-source algorithm incorporating a transformer-based video classifier are combined to automatically detect and classify urine and fecal deposits made by male and female mice and their spatio-temporal dynamics during behavioral tests.
    1. Neuroscience

    A neural network model that generates salt concentration memory-dependent chemotaxis in Caenorhabditis elegans

    Masakatsu Hironaka, Tomonari Sumi
    Reversible synaptic plasticity between sensory neurons and interneurons, switching between inhibitory and excitatory, underpins the neural basis of salt concentration memory-dependent preference reversal in Caenorhabditis elegans.
    1. Neuroscience

    Optogenetic silencing of hippocampal inputs to the retrosplenial cortex causes a prolonged disruption of spatial working memory

    Bárbara Pinto-Correia, Patrícia Caldeira-Bernardo, Miguel Remondes
    Light-activating a proton pump (eArchT) to silence hippocampal synaptic terminals in the rodent retrosplenial cortex caused a spatial working memory impairment affecting interleaved trials where no light was delivered.
    1. Neuroscience

    Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex

    Louis Richevaux, Dongkyun Lim ... Desdemona Fricker
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Neural signatures of motor memories emerge in neural network models

    Joanna C Chang, Claudia Clopath, Juan A Gallego
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    Coordinated dynamics of excitatory and inhibitory synapse assembly

    Krassimira Garbett, James Allen, Richard C Sando
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    • Convincing