Browse our latest Neuroscience articles

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    1. Neuroscience

    Cell-intrinsic mechanisms of temperature compensation in a grasshopper sensory receptor neuron

    Frederic A Roemschied, Monika JB Eberhard ... Susanne Schreiber
    The firing rates of neurons in the grasshopper auditory system are surprisingly robust to changes in temperature, and cell-intrinsic mechanisms are sufficient to explain this temperature insensitivity.
    1. Neuroscience

    Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis

    Nicolas X Tritsch, Won-Jong Oh ... Bernardo L Sabatini
    The molecular mechanisms by which midbrain dopamine neurons acquire the inhibitory neurotransmitter GABA for synaptic release are revealed.
    1. Neuroscience

    RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling

    Olga Ostrovskaya, Keqiang Xie ... Kirill A Martemyanov
    A critical regulator of inhibitory neurotransmitter signaling in the hippocampus has been identified in experiments on mice and been shown to play essential role in synaptic plasticity and memory.
    1. Neuroscience

    SIR-2.1 integrates metabolic homeostasis with the reproductive neuromuscular excitability in early aging male Caenorhabditis elegans

    Xiaoyan Guo, L René García
    A protein called SIR-2.1 helps to protect worms from the effects of aging by regulating metabolic processes that would otherwise generate damaging reactive oxygen species.
    1. Neuroscience

    Gating of neural error signals during motor learning

    Rhea R Kimpo, Jacob M Rinaldi ... Jennifer L Raymond
    Electrode recordings and optogenetics reveal that the cerebellum can modulate its response to error signals from the brainstem during motor learning.
    1. Neuroscience

    Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling

    Marlen Zschätzsch, Carlos Oliva ... Bassem A Hassan
    Asymmetric localization of the receptor EGFR within branches of axons is required to establish the precise wiring of neuronal networks within the Drosophila brain.
    1. Neuroscience

    A frontal cortex event-related potential driven by the basal forebrain

    David P Nguyen, Shih-Chieh Lin
    Contrary to the common belief that cognitive event-related potentials are generated by local activity within the cerebral cortex, it is shown that some of these potentials are modulated by subcortical inputs.
    1. Neuroscience

    Neuropathic Pain: The pros and cons of degeneracy

    Jean-Marc Goaillard, Martial A Dufour
    Version of Record
    Insight
    1. Neuroscience

    Criticality and degeneracy in injury-induced changes in primary afferent excitability and the implications for neuropathic pain

    Stéphanie Ratté, Yi Zhu ... Steven A Prescott
    No single molecular change is uniquely necessary to cause neuropathic changes in primary afferent excitability; multiple different changes are sufficient.
    1. Neuroscience

    CA1 cell activity sequences emerge after reorganization of network correlation structure during associative learning

    Mehrab N Modi, Ashesh K Dhawale, Upinder S Bhalla
    As mice learn to associate events separated in time, neurons within the CA1 region of the hippocampus progressively reorganize their firing patterns, leading to a relay of cellular activity that bridges the two events.