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Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.
Bioacoustics: Characterizing the hum of hovering animals
The sounds of flying animals, such as the hum of a hummingbird as it hovers, are influenced by the unique forces generated by the flapping of their wings.
Navigation: Why flies look to the skies
Fruit flies rely on an intricate neural pathway to process polarized light signals in order to inform their internal compass about the position of the Sun.
Biochemistry and Chemical Biology
Virus Engineering: ORACLE reveals a bright future to fight bacteria
Willow Coyote-Maestas, James S Fraser
A new way to alter the genome of bacteriophages helps produce large libraries of variants, allowing these bacteria-killing viruses to be designed to target species harmful to human health.
Chromosomes and Gene Expression
Cardiovascular Disease: Exploring risk factors at the molecular level
Martina Rudnicki, Tara L Haas
Risk factors for cardiovascular diseases trigger molecular changes that harm the endothelial cells in the heart, but exercise can suppress these effects.
Microbiology and Infectious Disease
Antibiotic Resistance: Bacterial evolution on demand
Pål J Johnsen et al.
Bacteria carry antibiotic resistant genes on movable sections of DNA that allow them to select the relevant genes on demand.
Epidemiology and Global Health
Malaria: What happens when forests fall?
Mercedes Pascual, Andres Baeza
Combining spatial and temporal data is helping researchers to understand how deforestation influences the risk of malaria.
Remodeling Synapses: From mice to men
J Christian Althaus, Michael A Sutton
All-trans retinoic acid induces functional and structural plasticity of synapses in human cortical circuits through the engagement of the spine apparatus.
Genetics and Genomics
COVID-19: Rare variants increase the risk of severe COVID-19
Frank L van de Veerdonk, Mihai G Netea
Evidence is mounting that rare loss-of-function variants in the
gene predispose men with no medical history to severe forms of COVID-19.
Microbiome: Taming the beasts inside
Erica P Ryu, Emily R Davenport
Changes in diet associated with domestication may have shaped the composition of microbes found in the guts of animals.
Climate Classification: Exploring a new way to think about climate regions
Barnabas H Daru
A new system for classifying climates emerges from modeling the environmental conditions that 26,000 species of tetrapods experience in their home range.
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