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Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.
Immunology and Inflammation
Skin Immunity: A new player in the dermis
Gyohei Egawa, Kenji Kabashima
Langerhans-like cells located in the dermis can travel to lymph nodes where they modulate immune responses.
Genetics and Genomics
Aging: The temporary cost of dominance
Calen P Ryan, Christopher W Kuzawa
In a population of wild baboons, a new way to assess biological age reveals a surprising effect of social hierarchy.
Fertilization: Conserved sperm factors are no longer a bone of contention
Xue Mei, Andrew Singson
Proteins related to a molecule involved in the formation of osteoclasts in bone are required for fertilization in worms, flies and mammals.
Physics of Living Systems
Flagella: A new kind of beat
Kirsty Y Wan
New mathematical model reveals how the flagella of some single-celled algae generate a lasso-like beat pattern that propels the cell through water.
Physics of Living Systems
Tumor Biology: Cells under pressure
Dhiraj Indana, Ovijit Chaudhuri
A new method for applying solid stress to aggregates of cells is shedding light on the impact of mechanical forces on cancer cells.
Bioacoustics: Characterizing the hum of hovering animals
The sounds of flying animals, such as the hum of a hummingbird as it hovers, are influenced by the unique forces generated by the flapping of their wings.
Navigation: Why flies look to the skies
Fruit flies rely on an intricate neural pathway to process polarized light signals in order to inform their internal compass about the position of the Sun.
Biochemistry and Chemical Biology
Virus Engineering: ORACLE reveals a bright future to fight bacteria
Willow Coyote-Maestas, James S Fraser
A new way to alter the genome of bacteriophages helps produce large libraries of variants, allowing these bacteria-killing viruses to be designed to target species harmful to human health.
Chromosomes and Gene Expression
Cardiovascular Disease: Exploring risk factors at the molecular level
Martina Rudnicki, Tara L Haas
Risk factors for cardiovascular diseases trigger molecular changes that harm the endothelial cells in the heart, but exercise can suppress these effects.
Microbiology and Infectious Disease
Antibiotic Resistance: Bacterial evolution on demand
Pål J Johnsen et al.
Bacteria carry antibiotic resistant genes on movable sections of DNA that allow them to select the relevant genes on demand.
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