Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Cell Biology

    Centrioles: One master to rule them all

    Pablo Barbeito, Francesc R Garcia-Gonzalo
    Multiciliated cells rely on the same master regulator as dividing cells to amplify the number of centrioles needed to generate the hair-like structures that coat their cell surface.
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    1. Physics of Living Systems

    Navigation: Where is that smell coming from?

    Samuel Brudner, Thierry Emonet
    Computational model reveals why pausing to sniff the air helps animals track a scent when they are far away from the source.
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    1. Neuroscience

    Binge Drinking: How the brain regulates alcohol intake

    Leigh C Walker, Paulo Pinares-Garcia, Andrew J Lawrence
    A neural pathway involved in goal-oriented behaviours becomes dysregulated during binge drinking and alcohol use disorder.
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    1. Genetics and Genomics

    Plant Microbiome: How hungry roots get their microbes

    Maggie R Wagner
    Maize genes influence which species of bacteria are recruited from the soil, especially in the absence of nitrogen supplied by fertilizer.
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    1. Neuroscience

    Blindness: Rethinking the representation of sound

    Łukasz Bola
    Blindness triggers a reorganization of the visual and auditory cortices in the brain.
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    1. Structural Biology and Molecular Biophysics

    Photosynthesis: Surviving on low-energy light comes at a price

    Elisabet Romero
    Two species of photosynthetic cyanobacteria can thrive in far-red light but they either become less resilient to photodamage or less energy efficient.
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    1. Cell Biology

    Alternative Splicing: A new role for Hif-1α

    Mingyu Shin, Jiwon Shim
    A gene normally involved in responding to hypoxia helps to protect insect muscles during migratory flight in a non-oxygen dependent manner.
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    1. Cancer Biology

    Androgen Receptor: How splicing confers treatment resistance in prostate cancer

    Prathyusha Konda, Srinivas R Viswanathan
    A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside.
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    1. Medicine

    Gaucher Disease: Microglia orchestrate neuroinflammation

    Ricardo A Feldman
    Experiments in genetically altered mice reveal that microglia play an important role in the neurological damage associated with neuro-nopathic Gaucher disease.
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Development: Shining a light on hematopoietic stem cells

    Anne Schmidt
    A combination of light and electron microscopy has revealed further details about the location and interactions of hematopoietic stem and progenitor cells.
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