Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Computational and Systems Biology
    2. Ecology

    Fermentation: Teaming up to make kombucha

    Olga Ponomarova
    Reducing the microbial diversity in a type of fermented tea reveals the core metabolic interactions responsible for the drink’s signature taste and characteristics.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Evolution: Poor eyesight reveals a new vision gene

    Tathagata Biswas et al.
    Comparing the genomes of mammals which evolved to have poor vision identifies an important gene for eyesight.
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    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Adaptive Immunity: Maintaining naivety of T cells

    Ken Duffy
    Mathematical models encoding biological hypotheses reveal new insight into the dynamics of naive immune cells in mice from birth to old age.
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    1. Neuroscience

    Brain: Connecting the lines after a stroke

    S Thomas Carmichael
    In mice, stimulating cortical areas in the undamaged hemisphere of a brain affected by stroke impairs recovery.
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    1. Cell Biology

    Cell Mechanics: Under the hood of a moving cell

    Guillaume Romet-Lemonne
    Experiments using purified proteins reveal how the network of filaments that underlie cell movement becomes denser when pushing against a stronger mechanical force.
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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Protease Inhibitors: Developing evolution-resistant drugs for COVID-19

    Daniel M Weinreich
    Analyzing how mutations affect the main protease of SARS-CoV-2 may help researchers develop drugs that are effective against current and future variants of the virus.
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    1. Computational and Systems Biology
    2. Physics of Living Systems

    Bacteria: To biofilm or not to biofilm

    Shravan Pradeep, Paulo E Arratia
    A new model helps to predict under which conditions a species of bacteria will switch to a static lifestyle.
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    1. Computational and Systems Biology
    2. Stem Cells and Regenerative Medicine

    Cell Culture: Implementing robotics and artificial intelligence

    Sujith Sebastian
    An automated platform for cell culture combines robotics and artificial intelligence to optimize cell culture protocols and reliably produce specific cell types that could be used for regenerative medicine treatments.
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    1. Genetics and Genomics

    Genetic Effects: Accounting for diet and age

    Hélène Tonnelé, Amelie Baud
    The diet and age of mice can modulate how different genetic variants impact body weight, demonstrating the need to take context into account when performing genetic studies.
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    1. Genetics and Genomics
    2. Structural Biology and Molecular Biophysics

    Mutational Scanning: Ion-ing out the genetic variants of Kir2.1

    Braden S Fallon, Justin G English
    Deep mutational scanning provides new insights into how mutations alter the expression and activity of the potassium ion channel Kir2.1, which is associated with many diseases.
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