Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Microbiology and Infectious Disease

    Parasite Transmission: A two-stage solution

    Fabien Guegan, Luisa Figueiredo
    The parasite that causes African sleeping sickness can be transmitted from mammals to tsetse flies in two stages of its lifecycle, rather than one as was previously thought.
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    1. Epidemiology and Global Health
    2. Immunology and Inflammation

    Inflammation: Western diet shifts immune cell balance

    Christina M Bergey
    The immune cells of macaques fed a Western-like diet adopt a pro-inflammatory profile.
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    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Ancient Viruses: How infectious diseases arrived in the colonial Americas

    Ville N Pimenoff, Charlotte J Houldcroft
    Analysis of viral DNA from human remains suggests that the transatlantic slave trade may have introduced new pathogens that contributed to the devastating disease outbreaks in colonial Mexico.
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    1. Evolutionary Biology

    Antibiotic Resistance: Finding the right sequence of drugs

    Anh Huynh, Kevin B Wood
    Rapidly switching between similar antibiotics may help to slow down the evolution of resistance.
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    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Disease: Deciphering the triad of infection, immunity and pathology

    Frederik Graw
    The factors which drive and control disease progression can be inferred from mathematical models that integrate measures of immune responses, data from tissue sampling and markers of infection dynamics.
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    1. Ecology
    2. Microbiology and Infectious Disease

    Microbiome: What can we learn from honey bees?

    Julia A Schwartzman
    The Western honey bee provides a model system for studying how closely related species of bacteria are able to coexist in a single community.
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Malaria: A genetic intervention

    Colin Sutherland, Didier Menard
    A tool that analyzes the genome of parasites found in the blood of malaria patients can help inform policy decisions on how best to tackle the rise in drug-resistant infections.
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    1. Epidemiology and Global Health

    Mortality: A comprehensive look at the COVID-19 pandemic death toll

    Lone Simonsen, Cecile Viboud
    COVID-19 ‘excess mortality’ has been estimated for more than 100 countries and shows a dramatic death toll in many countries.
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    1. Neuroscience

    Neurohormones: A major new dimension in the problem of brain injury

    Jonathan R Wolpaw, Jonathan S Carp
    Evidence that neurohormones contribute to the contralateral effects of unilateral brain injury challenges a fundamental assumption of basic neuroscience and clinical neurology.
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    1. Immunology and Inflammation

    Autoimmune Disease: When a virus lies in wait

    David Taussig, Yariv Wine
    A mouse model supports the hypothesis that latent Epstein–Barr virus exacerbates the symptoms of rheumatoid arthritis.
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