Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Neuroscience

    Optogenetics: Exciting inhibition in primates

    Wim Vanduffel, Xiaolian Li
    A new genetic marker enables precise control over a group of inhibitory neurons in monkeys.
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    1. Developmental Biology
    2. Immunology and Inflammation

    Developmental Immunology: An atlas for hemocytes in an insect

    Samuel Liegeois, Dominique Ferrandon
    Single-cell RNA sequencing has revealed distinct subpopulations of hemocytes in fruit fly larvae.
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Antibiotic Resistance: Genomics against gonorrhoea

    Nicholas Medland
    Surveillance strategies based on whole genome sequencing could help with the early identification and detection of new forms of drug-resistant gonorrhoea.
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    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Anti-Cancer Drugs: The mitochondrial paradox

    Sophie L Penman et al.
    A structural motif that is found in two cancer drugs may be responsible for their ability to tackle cancers and for the side-effects caused by the drugs.
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    1. Evolutionary Biology

    Neuropeptide Signaling: Unravelling the evolutionary history of kisspeptin

    Maria I Arnone, Paola Oliveri
    Experiments in sea cucumbers reveal how the physiological responses regulated by a neuropeptide called kisspeptin have evolved.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Homing Genetic Elements: Mobile DNAs and switching mating types in yeast

    Laura N Rusche
    The gene that allows budding yeast cells to switch their mating type evolved from a newly discovered family of genes named weird HO.
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    1. Epidemiology and Global Health

    Aging and Geroscience: Putting epigenetic biomarkers to the test for clinical trials

    Jamie N Justice, Stephen B Kritchevsky
    Reliable biomarkers are needed to test the effectiveness of interventions intended to improve health and extend lifespan.
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    1. Neuroscience

    Memory: How the brain constructs dreams

    Erin J Wamsley
    Deep inside the temporal lobe of the brain, the hippocampus has a central role in our ability to remember, imagine and dream.
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    1. Developmental Biology
    2. Evolutionary Biology

    Extracellular Matrix: Sculpting new structures

    Jocelyn A McDonald, Yoshinori Tomoyasu
    The origins of the posterior lobe, a recently evolved structure in some species of Drosophila, have become clearer.
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    1. Microbiology and Infectious Disease

    HIV in Women: How HIV exploits T cells in the endometrium

    Marta Rodriguez-Garcia
    Immune cells in the endometrium are targeted by HIV and re-programmed to allow them to survive and spread the virus throughout the body.
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