Insights

Latest articles

1. 1. Neuroscience

   Vision: Framing orientation selectivity

   Floris P de Lange, Matthias Ekman

   The ongoing debate on the neural basis of orientation selectivity in the primary visual cortex continues.
2. 1. Cancer Biology
   2. Immunology and Inflammation

   Contagious Cancers: A ‘devil’ of a problem

   Victoria L Hansen, Robert D Miller

   The discovery of a second facial tumor disease in the Tasmanian devil has provided insights into the emergence of contagious cancers.
3. 1. Computational and Systems Biology

   Protein Overexpression: Reaching the limit

   Benedetta Bolognesi, Ben Lehner

   How many copies of a protein can be made before it becomes toxic to the cell?
4. 1. Structural Biology and Molecular Biophysics

   Ion Channels: Exploiting natural regulation

   Catherine Proenza

   Using a short peptide to regulate the activity of HCN ion channels illustrates how physiological modulators could inspire new drugs. .
5. 1. Developmental Biology
   2. Evolutionary Biology

   Patterning: Fishing for ancestry

   Hannah Brunsdon, E Elizabeth Patton

   The same genes and signalling pathways control the formation of skin appendages in both fish and land animals.
6. 1. Microbiology and Infectious Disease
   2. Structural Biology and Molecular Biophysics

   Viruses: The secrets of the stability of the HIV-1 capsid

   Martin Obr, Hans-Georg Kräusslich

   Structural and biophysical studies help to follow the disassembly of the HIV-1 capsid in vitro, and reveal the role of a small molecule called IP6 in regulating capsid stability.
7. 1. Neuroscience

   Sound localization: These are not the neurons you are looking for

   Victor Benichoux, Daniel J Tollin

   Studies that looked into how the auditory brainstem processes the difference in the intensity of a sound as it reaches each ear may have wrongly assumed which neurons were being recorded.
8. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Mechanobiology: A brighter force gauge for cells

   Victor Pui-Yan Ma, Khalid Salaita

   An improved biosensor sheds new light on tension within proteins.
9. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Phenotypic Diversity: Setting the bar

   Charles Y Feigin, Ricardo Mallarino

   Analyzing the genomes of rock pigeons demonstrates that genetic variation comes in many forms and can have unexpected origins.
10. 1. Cancer Biology

    Pancreatic Cell Fate: To be or not to be

    Zhe Zhang, Elisabeth Hessmann

    Chromatin remodeling processes can drive acinar cell fate decisions.