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Latest articles

1. 1. Neuroscience

   Neurodegeneration: Fly model sheds light on brain disease

   Martin H Berryer et al.

   Experiments on flies suggest that a gain-of-function mechanism in a protein called CSPɑ contributes to the progressive brain disease CLN4.
2. 1. Genetics and Genomics

   Genetic Variation: Searching for solutions to the missing heritability problem

   Luisa F Pallares

   Rare genetic variants in yeast explain a large amount of phenotypic variation in a complex trait like growth.
3. 1. Developmental Biology
   2. Microbiology and Infectious Disease

   Plant Disease: Cycling in synchrony

   Míriam Osés-Ruiz, Nicholas J Talbot

   The corn smut fungus uses two different mechanisms to control its cell cycle when it is infecting plants.
4. 1. Immunology and Inflammation
   2. Neuroscience

   Autoimmunity: Bringing on the itch

   Daniel A Waizman et al.

   Neutrophils are the first immune cells that enter the skin and cause itch in atopic dermatitis.
5. 1. Cell Biology
   2. Evolutionary Biology

   Multicellularity: How contraction has shaped evolution

   Mukund Thattai

   Two new unicellular organisms reveal that coordinated contractions of groups of cells using actomyosin predated animal multicellularity during evolution.
6. 1. Neuroscience

   Behavior: The cerebellum shows its stripes

   Ashley L Holloway, Talia N Lerner

   New studies examine how the different sub-structures in the cerebellum are organized to receive information during complex behavioral tasks.
7. 1. Neuroscience

   Brain Development: The impact of light during the night

   Sophia TC Leung et al.

   Exposing chicks to one hour of light during the night disrupts the releaseof a hormone that is needed by cells in the developing brain to survive.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Regeneration: Lymphatic vessels help mend broken hearts

   Catherine Pfefferli, Anna Jaźwińska

   Experiments on zebrafish show that the regeneration of the heart after an injury depends on lymphatic vessels.
9. 1. Biochemistry and Chemical Biology

   Enzyme Mechanisms: Wedging open a catalytic site

   Annie Beuve

   The activation mechanism of the nitric oxide receptor has been revealed by cryo-electron microscopy.
10. 1. Neuroscience

    Prefrontal Cortex: A tale of two pathways

    Jonathan A Oler, Julie L Fudge

    A combination of invasive and non-invasive techniques has allowed researchers to take a closer look at the two major neural pathways that connect the amygdala and the prefrontal cortex.