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Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.
Human Biology and Medicine
Autism: Balancing excitation and inhibition in the autistic brain
Charlotte M Pretzsch, Dorothea L Floris
A metric called the Hurst exponent could be a useful biomarker for studies exploring brain differences between men and women with autism spectrum disorder.
Ecosystems: The diversity of decay
Emma J Sayer, Ralf Schäfer
To predict how species loss will affect ecosystems, it is important to consider how biodiversity influences processes such as decomposition.
Neurogenesis: Delayed gratification in the adult brain
Some immature neurons in the cerebral cortex of mammals might wait for years before they become activated and finish their development.
Neural Circuits: Turning away from danger
Jun Liu, Monika Scholz
The flexible escape behavior exhibited by
in response to threats relies on a combination of feedback and feedforward circuits.
Physics of Living Systems
Structural Biology and Molecular Biophysics
Phase Separation: Restricting the sizes of condensates
Furqan Dar, Rohit Pappu
Computer simulations of model proteins with sticker-and-spacer architectures shed light on the formation of biomolecular condensates in cells.
Optogenetics: Exciting inhibition in primates
Wim Vanduffel, Xiaolian Li
A new genetic marker enables precise control over a group of inhibitory neurons in monkeys.
Immunology and Inflammation
Developmental Immunology: An atlas for hemocytes in an insect
Samuel Liegeois, Dominique Ferrandon
Single-cell RNA sequencing has revealed distinct subpopulations of hemocytes in fruit fly larvae.
Epidemiology and Global Health
Microbiology and Infectious Disease
Antibiotic Resistance: Genomics against gonorrhoea
Surveillance strategies based on whole genome sequencing could help with the early identification and detection of new forms of drug-resistant gonorrhoea.
Biochemistry and Chemical Biology
Anti-Cancer Drugs: The mitochondrial paradox
Sophie L Penman et al.
A structural motif that is found in two cancer drugs may be responsible for their ability to tackle cancers and for the side-effects caused by the drugs.
Neuropeptide Signaling: Unravelling the evolutionary history of kisspeptin
Maria I Arnone, Paola Oliveri
Experiments in sea cucumbers reveal how the physiological responses regulated by a neuropeptide called kisspeptin have evolved.
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