Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Computational and Systems Biology
    2. Medicine

    Heart Attack: Working together

    Regan Odongo, Tunahan Çakır
    Heart attacks have a ripple effect on how other organs exchange biomolecules that help the heart respond to injury.
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    1. Cell Biology

    Metabolism: A move in response to starvation

    Rebecca Martina Fausten, Maria Bohnert
    When a yeast cell runs out of fuel, it can increase the flux through a central metabolic pathway by simply changing the location of an enzyme.
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    1. Cell Biology
    2. Microbiology and Infectious Disease

    HIV-1 Infection: You can keep your coat on

    Gregory J Bedwell, Alan N Engelman
    High-resolution imaging techniques reveal new insights into the actions of the retrovirus HIV-1 inside host cells.
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    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    Cancer: Beware the algorithm

    Peter van Endert
    Spliced peptides present on tumor cells can help to mount an immune response, but algorithms offer limited help in predicting which ones actually exist and perform this role in vivo.
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    1. Cell Biology

    Cellular Organisation: Putting organelles in their place

    Patricia Ulm, Verena Jantsch
    Experiments in C. elegans reveal new insights into how the ANC-1 protein helps to anchor the nucleus and other organelles in place.
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    1. Microbiology and Infectious Disease

    COVID-19: Avoiding culture shock with the SARS-CoV-2 spike protein

    Benjamin G Hale
    When culturing SARS-CoV-2 in the laboratory it is vital to avoid deletions in the gene for the spike protein that could affect the interpretation of experiments.
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    1. Cancer Biology

    Tumour Initiation: Danger zone

    Zohra Butt, Ian Prior
    What level of Ras genes activity leads to the development of cancer?
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    1. Immunology and Inflammation

    Skin Immunity: A new player in the dermis

    Gyohei Egawa, Kenji Kabashima
    Langerhans-like cells located in the dermis can travel to lymph nodes where they modulate immune responses.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Aging: The temporary cost of dominance

    Calen P Ryan, Christopher W Kuzawa
    In a population of wild baboons, a new way to assess biological age reveals a surprising effect of social hierarchy.
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    1. Developmental Biology

    Fertilization: Conserved sperm factors are no longer a bone of contention

    Xue Mei, Andrew Singson
    Proteins related to a molecule involved in the formation of osteoclasts in bone are required for fertilization in worms, flies and mammals.
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