Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Biochemistry and Chemical Biology

    Convergent Evolution: Shaping the import system of mitochondria

    Kostas Tokatlidis
    Evidence is accumulating that unrelated species have independently evolved the same way of importing proteins in their mitochondria.
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    1. Biochemistry and Chemical Biology

    In Vitro Evolution: Rethinking the tools of the RNA world

    Antony Crisp, Thomas Carell
    An artificially evolved ribozyme can catalyse the synthesis of RNA by using trinucleotide triphosphates as building blocks.
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    1. Structural Biology and Molecular Biophysics

    Electrophysiology: Leading the charge

    Andrew JR Plested
    A simple label-free method uses the electrical properties of cells to detect how ligands bind to membrane proteins.
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    1. Developmental Biology
    2. Immunology and Inflammation

    Chemokines: The cell sets the tone

    Jonna Alanko, Michael Sixt
    In zebrafish larvae, it is the cell type that determines how the cell responds to a chemokine signal.
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    1. Biochemistry and Chemical Biology

    RNA World: Visualizing primer extension without enzymes

    John C Chaput
    X-ray crystallography has been used to observe the synthesis of RNA in the absence of enzymes with atomic resolution.
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    1. Microbiology and Infectious Disease

    HIV-1 Latency: Coloring hidden viruses

    Marina Lusic
    An improved dual-color reporter reveals how the fate of latent HIV-1 depends on where it integrates in the human genome.
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    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Pharmacology: A Swiss army knife for targeting receptors

    Johansen B Amin, Lonnie P Wollmuth
    A compound can change the activity of NMDA receptors in some regions of a synapse without affecting those in other regions.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Influenza virus: Interfering with transmission

    Andreas Wack
    The IFNλ family of interferons controls the spread of viruses in the upper respiratory tract and transmission between mice.
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    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Pollution: Transgenic pigs to the rescue

    Björn Petersen
    Genetically engineered pigs that digest their food better could help to reduce phosphorus and nitrogen pollution.
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    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromocenters: Bundling up DNA

    Susan A Gerbi
    Structures known as chromocenters, comprising satellite DNA and proteins such as D1 or HMGA1, help to contain DNA inside the nucleus between cell divisions.
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