Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Evolutionary Biology

    Fecal Microbiomes: Baboons, bacteria, and biological clocks address an age-old question

    Amanda D Melin
    Studying the fecal microbiota of wild baboons helps provide new insight into the factors that influence biological aging.
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    1. Neuroscience

    Brain Activity: Unifying networks of a rhythm

    Mohsen Alavash
    Combining electrophysiological, anatomical and functional brain maps reveals networks of beta neural activity that align with dopamine uptake.
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    1. Neuroscience

    Navigation: Building a cognitive map through self-motion

    Bharath Krishnan, Noah Cowan
    Mice can generate a cognitive map of an environment based on self-motion signals when there is a fixed association between their starting point and the location of their goal.
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    1. Cell Biology

    Microbiome: Balancing microbial composition through diet

    L Catalina Acuff, Karen Guillemin
    A reciprocal interaction between gut bacteria and gut cells affects protein absorption in the host.
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    1. Immunology and Inflammation

    Autoimmunity: The epigenetic trajectory of type 1 regulatory T cells

    David P Turicek, Xiaoxiao Wan
    The epigenome of T follicular helper cells prepares them for conversion into type 1 regulatory T cells.
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    1. Developmental Biology

    Neuronal Development: Rethinking sensorimotor circuits

    Maarten F Zwart
    New research shows that the neural circuit responsible for stabilising gaze can develop in the absence of motor neurons, contrary to a long-standing model in the field.
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    1. Microbiology and Infectious Disease

    Gut Microbes: Regulating uric acid

    Caihong Hu
    Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
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    1. Cancer Biology
    2. Genetics and Genomics

    Cancer: Predicting drug resistance

    Nicole S Arellano, Shannon E Elf
    A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukemia and how this influences treatment outcomes.
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    1. Stem Cells and Regenerative Medicine

    Cell Death: Caspases promote cell proliferation after necrosis

    Prathibha Yarikipati, Andreas Bergmann
    An enzyme known as caspase, which initiates apoptosis, has a central role in the regeneration of cells and repair of tissue that can occur after necrosis.
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    1. Stem Cells and Regenerative Medicine

    Notch Signaling: Antibodies get under the skin

    Chiara Levra Levron, Gabriele Piacenti, Giacomo Donati
    By inhibiting receptor-ligand interactions in sebaceous glands, antibodies may be able to treat certain skin conditions.
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