Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Genome Organization: The loopy world of cohesin

    Kazuhiro Maeshima, Shiori Iida
    DNA loops can be formed by a mechanism in which the cohesin complex pulls DNA strands through its ring structure using biased Brownian motion.
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    1. Neuroscience

    Neurotransmission: The secret life of memory receptors

    Hovy Ho-Wai Wong et al.
    The canonical hippocampal NMDA memory receptor also controls the release of the transmitter glutamate and the growth factor BDNF.
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    1. Evolutionary Biology

    Dinosaurs: A new, ‘hip’ way to breathe

    Marc R Spencer
    Ornithischians, one of the three major groups of dinosaurs, developed a unique mechanism to ensure airflow in the lungs.
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    1. Chromosomes and Gene Expression

    Translation: The long and short of it

    Lori A Passmore, Terence TL Tang
    Longer poly(A) tails improve translation in early development, but not in mature cells that have higher levels of the protein PABPC.
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    1. Cell Biology
    2. Medicine

    Pigmentation: Watching hair turn grey

    Michael P Philpott
    Analysing changes in hair pigmentation may lead to a better understanding of the impacts of ‘life events’ on human biology and aging.
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    1. Epidemiology and Global Health
    2. Medicine

    Health: Going beyond lifestyle factors

    Milagros Ruiz
    Wealth and inequality impact blood pressure in a population with the lowest risk of heart disease in the world.
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    1. Neuroscience

    Antidepressants: Where ketamine and dopamine collide

    David J Marcus, Michael R Bruchas
    Ketamine strengthens connections between two brain regions that are involved in the production and regulation of dopamine, which may explain how the drug can alleviate depression.
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    1. Biochemistry and Chemical Biology

    Membrane Fusion: Molecular machinery turns full circle

    Josep Rizo et al.
    Two proteins called Sec17 and Sec18 may have a larger role in membrane fusion than is commonly assumed in textbook models.
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    1. Microbiology and Infectious Disease
    2. Plant Biology

    Bacterial Blooms: The social life of cyanobacteria

    Conrad W Mullineaux, Annegret Wilde
    The cyanobacterium Synechocystis secretes a specific sulphated polysaccharide to form floating cell aggregates.
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    1. Ecology
    2. Plant Biology

    Plant Ecology: Getting the metabolites right

    Arthur Korte
    A study of almost 800 Arabidopsis thaliana plants from across Europe reveals how the environment and evolutionary pressures shape their metabolites.
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