Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Enzymes: The two roles of complex III in plants

    Hans-Peter Braun
    Atomic structures of mitochondrial enzyme complexes in plants are shedding light on their multiple functions.
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    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Polygenic Scores: How well can we separate genetics from the environment?

    Jennifer Blanc, Jeremy J Berg
    A simulation study demonstrates a better method for separating genetic effects from environmental effects in genome-wide association studies, but there is still some way to go before this becomes a "solved" problem.
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    1. Neuroscience

    Blood Flow: Supplying the sleeping brain

    Stephanie D Williams, Laura D Lewis
    During sleep, the brain experiences large fluctuations in blood volume and altered coupling between neural and vascular signals.
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    1. Evolutionary Biology

    Telomeres: Change and HOAP for the best

    Claudia Castillo-González, Dorothy E Shippen
    HOAP is a telomere-binding protein that has a conserved role in Drosophila, but it also needs to evolve quickly to restrict telomeric retrotransposons.
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    1. Genetics and Genomics

    Metabolism: Muscle signals to the rescue

    Arely V Diaz, Tânia Reis
    The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Viruses: Neutralizing SARS-CoV-2

    Eric Poeschla
    Experiments with hybrid viruses are illuminating how SARS-CoV-2 can escape neutralizing antibodies.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Genome Reduction: Does size really matter?

    David G Heckel
    Analysis of the smallest known arthropod genome reveals a mechanism for genome reduction that appears to be driven by a specialized ecological interaction with plants.
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    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Genetic Engineering: Increasing the uptake of carbon dioxide

    Eric Franklin, Martin Jonikas
    A mechanism for concentrating carbon dioxide has for the first time been successfully transferred into a species that lacks such a process.
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    1. Computational and Systems Biology
    2. Neuroscience

    Deep Learning: Tackling the challenges of bioimage analysis

    Daniël M Pelt
    Using multiple human annotators and ensembles of trained networks can improve the performance of deep-learning methods in research.
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    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Sperm: The secrets of success

    Kayla M Komondor, Anne E Carlson
    Imaging sperm as they travel through the female reproductive tract has revealed new details about fertilization at the molecular level.
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