Insights

Latest articles

1. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Cancer: Reading the DNA of telomeres

   Shamayita Roy, Claus M Azzalin

   Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.
2. 1. Medicine

   Aging: Multiple roles for a mitochondrial enzyme

   Xicong Tang, Hongyu Qiu

   The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.
3. 1. Neuroscience

   Touch: A lasting impression

   Rochelle Ackerley, Roger H Watkins

   Touch-sensitive neurons in the fingertips take previous physical contacts into account when relaying tactile information to the brain.
4. 1. Neuroscience

   Neurodevelopmental Disorders: Unraveling the impact of genetic variants

   Bruce Herring

   Experiments in mice reveal how three rare mutations in a gene called TRIO can lead to different neurodevelopmental outcomes.
5. 1. Immunology and Inflammation

   Interferon Signaling: Immobilizing bacteria to prevent infections

   Patricia Reist Iscar, Petr Broz

   The interferon-induced GTPase GVIN1 prevents bacteria from spreading among cells by coating them and rendering them immobile.
6. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Cell Surface Receptors: Virus attacks fish by muscling its way into cells

   Ping-Ping Liu, Zhe Wei, Xian-Wei Wang

   Nervous necrosis virus typically enters host cells via endocytosis, but it can also enter via a process called macropinocytosis.
7. 1. Microbiology and Infectious Disease

   Helicase Loading: A back-up mechanism for replication

   Godefroid Charbon, Anders Løbner-Olesen

   A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.
8. 1. Neuroscience

   Consciousness: Did you see it?

   Ling Liu

   Cautious reporting choices can artificially enhance how well analyses of brain activity reflect conscious and unconscious experiences, making distinguishing between the two more challenging.
9. 1. Cell Biology
   2. Neuroscience

   Vision: A pathway to sight

   Katherine J Wert

   The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.
10. 1. Neuroscience

    Synaptic Plasticity: A new mode of action for unconventional NMDA receptors

    Ikuko Smith

    Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.