Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Microbiology and Infectious Disease

    Parasites: Eviction notice served on Toxoplasma

    Juan C Sánchez-Arcila, Kirk DC Jensen
    The gene RARRES3 uses an unexpected strategy to eliminate the parasite Toxoplasma gondii from human cells.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Plants: Why do sunflowers have invisible colors?

    Jason Laurich, Anna M O'Brien
    In the common sunflower, patterns of UV-absorbing pigments are controlled by a newly identified regulatory region and may be under the influence of environmental factors.
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    1. Neuroscience

    Memory: Overwriting the past with supervised plasticity

    Xingyun Wang, Richard Naud
    Triggered activity bursts in place cells can increase and decrease the strength of some inputs.
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    1. Immunology and Inflammation

    Viruses: What triggers inflammation in COVID-19?

    Tomohiro Sawa, Takaaki Akaike
    The spike protein of SARS-CoV-2 triggers macrophages and epithelial cells to produce excess levels of pro-inflammatory molecules, which can do more harm than good.
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Regeneration: A matter of nerves

    Timothy J Duerr, James R Monaghan
    Regrowing new body parts requires neural input to restore appropriately sized limbs in salamanders.
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    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Photosynthesis: Oxygen overload

    Britta Foerster
    A structure that helps algae photosynthesize when carbon dioxide levels are low may also play a role during hyperoxia conditions.
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    1. Computational and Systems Biology
    2. Neuroscience

    Motor Control: Sensory feedback can give rise to neural rotations

    Omid G Sani, Maryam M Shanechi
    Investigating how an artificial network of neurons controls a simulated arm suggests that rotational patterns of activity in the motor cortex may rely on sensory feedback from the moving limb.
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    1. Evolutionary Biology

    Division of Labour: Losing out to improve group fitness

    Jos Kramer, Rolf Kümmerli
    A mathematical model provides clues as to why members of a group divide tasks between them even when specialisation reduces the performance of individuals.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Public Health: Add mass spectrometry to the pandemic toolbox

    Bart Van Puyvelde, Maarten Dhaenens
    A new protocol step improves robustness and ease-of-use for mass spectrometry in the clinic, opening the door to mass deployment to monitor infectious agents.
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    1. Cancer Biology
    2. Genetics and Genomics

    Mutations: When oncogenes do not cause cancer

    Jessica Shiu, Arthur D Lander
    Environmental cues, not oncogene-induced senescence, may stop melanocytes with an activating mutation in the BRAF gene from turning into melanoma.
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