Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Neuroscience

    Neuroendocrinology: Surging towards a better understanding of ovulation

    Lillian Rose, Alexander S Kauffman
    The ability to record the real-time activity of specialized neurons in the brains of female mice is providing new insights into the hormonal control of ovulation.
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    Insight
    1. Cell Biology
    2. Neuroscience

    Auditory Hair Cells: Examining the role of lipids in hearing

    Yein Christina Park, Angela Ballesteros
    The asymmetry of lipid membranes is tightly regulated in eukaryotic cells, and auditory hair cells are no exception.
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    Insight
    1. Biochemistry and Chemical Biology

    Lipid Transport: How membranes shape up for lipid transfer

    Takashi Hirashima, Toshiya Endo
    The extraction of a phospholipid called phosphatidic acid from the mitochondrial outer membrane is regulated by the curvature of this membrane.
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    Insight
    1. Neuroscience

    Vestibular Hair Cells: Are kinocilia motile?

    Ruth Anne Eatock, Marina Kabirova
    Gene expression patterns in the inner ear put an old question about structures called kinocilia back in motion.
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    Insight
    1. Neuroscience

    Neurotransmitters: The sound of neural silence

    Nikki Tjahjono, Yu-Shun Wang, Lin Tian
    A new fluorescent sensor makes it possible to track the neurotransmitter GABA in freely moving animals.
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    Insight
    1. Neuroscience

    Language Models: Does the brain really know what word is coming next?

    Richard J Antonello
    Apparent neural encoding of future words may arise from the statistical structure of language itself, rather than from predictive computations in the brain.
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    Insight
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Antibody Language Models: Taking the biology seriously makes models better

    Antonio Matas-Gil, Andreas Tiffeau-Mayer
    A new biologically-informed training paradigm enables protein language models to predict affinity maturation trajectories for antibodies.
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    Insight
    1. Neuroscience

    Neuroanatomy: Hidden folds reveal brain organization

    Jürgen Germann
    Previously underappreciated folds in the cerebral cortex provide insight into how its structure varies across individuals.
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    Insight
    1. Neuroscience

    Orbitofrontal Cortex: Cocaine disrupts hidden states in the brain

    Margo Le, Ronald Keiflin
    Cocaine use disrupts the encoding of abstract states in the orbitofrontal cortex.
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    Insight
    1. Structural Biology and Molecular Biophysics

    Glycobiology: How enzymes make the right choice during biosynthesis

    Ana S Ramírez, Camilo Perez
    The biosynthesis of an important biopolymer called hyaluronan requires an enzyme that discriminates between two different substrates.
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    Insight