Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    Heredity: The gene family that cheats Mendel

    J Dylan Shropshire, Antonis Rokas
    Some alleles of the wtf gene family can increase their chances of spreading by using poisons to kill other alleles, and antidotes to save themselves.
    Insight
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    1. Microbiology and Infectious Disease

    Malaria: Cracking Ali Baba’s code

    Oliver Billker
    A protein called P36 holds the key to how different species of malaria parasite invade liver cells.
    Insight
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    1. Neuroscience

    Maternal Behavior: Why mother rats protect their children

    Ksenia Z Meyza, Ewelina Knapska
    The presence of the hormone oxytocin in the central amygdala makes a mother rat willing to put her life in danger in order to protect her offspring.
    Insight
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    1. Cancer Biology

    Oncogene Regulation: Enhancers not required

    Ying Zheng, David Levens
    Laboratory mice with over half a megabase of DNA upstream of their Myc gene removed still thrive in the absence of stress.
    Insight
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    1. Immunology

    Cytokines: A gut response

    Matthew L Nicotra
    Unexpected findings from the immune system of sea urchin larvae potentially provide insights into immune signaling in ancestral lifeforms.
    Insight
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    1. Biophysics and Structural Biology

    Ion Channels: Poring over furrows

    Skylar ID Fisher, H Criss Hartzell
    Cryo-electron microscopy reveals the structure of a chloride channel that is closely related to a protein that transports lipids.
    Insight
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    1. Neuroscience

    Thermoregulation: How a brain keeps its cool

    Swathi Yadlapalli, Orie T Shafer
    Temperature-sensing neurons in the Drosophila brain cooperate with the central circadian clock to help regulate body temperature.
    Insight
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    1. Neuroscience

    Axons: The cost of communication in the brain

    Brian A MacVicar et al
    Imaging ATP in axons reveals that they rely on glucose from the blood and lactate produced by glial cells as sources of energy.
    Insight
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    1. Developmental Biology and Stem Cells

    Evolutionary Developmental Biology: Sensing oxygen inside and out

    Maria R Stupnikov, Wellington V Cardoso
    Neuroendocrine cells act as oxygen sensors in animals from fish to humans, but the evolutionary origins of these cells are only just becoming clear.
    Insight
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    1. Genomics and Evolutionary Biology

    Population Genetics: Global clues to the nature of genomic mutations in humans

    Aylwyn Scally
    An analysis of worldwide human genetic variation reveals the footprints of ancient changes in genomic mutation processes.
    Insight
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