Insights

Latest articles

1. 1. Cell Biology
   2. Genetics and Genomics

   Protein Homeostasis: How chloroplasts protect themselves from unfolded proteins

   Felix Kessler, Paolo Longoni

   A genetic screen has identified the first signaling component of the unfolded protein response in chloroplasts.
2. 1. Evolutionary Biology
   2. Genetics and Genomics

   Mating Behavior: When structure meets function

   Sarah A Signor

   A new study upturns the long-held belief that in fruit flies, the yellow gene determines sex-specific behaviors by acting in the brain.
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Neuropathy: Looking into nerve damage in the cornea

   Mihaela Gadjeva

   Interactions between T helper cells and the complement system promote loss of sensory neurons in the eye.
4. 1. Cell Biology
   2. Human Biology and Medicine

   Bone Formation: Sensing the load

   Nele Haelterman, Joohyun Lim

   How does the skeleton detect and adapt to changes in the mechanical load it has to carry?
5. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Tissue Engineering: Building a better model of the retina

   Milica Radisic

   Researchers have combined organ-on-a-chip engineering with the benefits of organoids to make improved models of the human retina.
6. 1. Evolutionary Biology
   2. Genetics and Genomics

   Reproduction: How flies turn food into progeny

   Thomas Flatt

   Sex-optimal diets have different effects on gene expression in female and male flies.
7. 1. Biochemistry and Chemical Biology

   Intracellular Organization: Getting ready for DNA duplication

   Nina Y Yao, Michael E O'Donnell

   The discovery of a biomolecular condensate involved in DNA replication has wide ranging implications.
8. 1. Ecology
   2. Evolutionary Biology

   Intergenerational Effects: How maternal adversity impacts offspring

   Zaneta M Thayer, Chlöe A Sweetman

   Adversities experienced by female baboons early in life can affect the survival of their offspring years later.
9. 1. Microbiology and Infectious Disease

   Bacterial Protein Secretion: Looking inside an injection system

   Sophie A Howard, Alain Filloux

   The proteins injected by bacteria into eukaryotic organisms can lead to fates as diverse as death and metamorphosis.
10. 1. Structural Biology and Molecular Biophysics

    Transcription: Overcoming chromatin barriers

    Babette E de Jong, John van Noort

    Single-molecule experiments reveal the dynamics of transcription through a nucleosome with single-base-pair accuracy.