Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Developmental Biology
    2. Evolutionary Biology

    Extracellular Matrix: Sculpting new structures

    Jocelyn A McDonald, Yoshinori Tomoyasu
    The origins of the posterior lobe, a recently evolved structure in some species of Drosophila, have become clearer.
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    1. Microbiology and Infectious Disease

    HIV in Women: How HIV exploits T cells in the endometrium

    Marta Rodriguez-Garcia
    Immune cells in the endometrium are targeted by HIV and re-programmed to allow them to survive and spread the virus throughout the body.
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    1. Neuroscience

    Motor Performance: Acetylcholine in action

    Erin M Wall, Sarah C Woolley
    The neurotransmitter acetylcholine influences how male finches perform courtship songs by acting on a region of the premotor cortex called HVC.
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    1. Cancer Biology
    2. Genetics and Genomics

    Tumor Evolution: Finding the mutations that drive resistance

    Nadine Bley
    Mutations that allow tumors to evolve and become resistant to treatment can be readily identified with a new sequencing approach.
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    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Immunogenetics: Untangling the immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca
    Interactions between immune cell receptors and proteins that determine disease susceptibility shed light on how different arms of the immune system are involved in three viral infections and Crohn's disease.
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    1. Cell Biology

    Bone: A role for fat precursors in the marrow

    Noriaki Ono
    A group of cells that can become adipocytes controls the formation of blood vessels in the bone marrow, and also regulates the differentiation of resident mesenchymal progenitor cells.
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    1. Microbiology and Infectious Disease

    Bacteria: Driving polar growth

    Neeraj Dhar
    Profiling the phenotype of 200,000 mutants revealed a new cofactor that may help a group of rod-shaped bacteria elongate and grow.
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    1. Human Biology and Medicine

    Drug Discovery: From worms to fish to mice

    Guy M Benian, Hyojung J Choo
    An multi-species approach can be used to identify small molecules with properties that might prove useful for the treatment of some neuromuscular diseases.
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    1. Stem Cells and Regenerative Medicine

    Stem Cells: Encouraging cartilage production

    H Scott Stadler
    A long non-coding RNA called GRASLND is essential to help stem cells create stable cartilage.
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    1. Genetics and Genomics
    2. Neuroscience

    Brain Development: Why the young sleep longer

    Budhaditya Chowdhury, Orie T Shafer
    A transcription factor helps young flies to sleep longer by delaying the maturation of a neural network that controls sleep.
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