Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Neuroscience

    Dopamine: Making memories

    Francesco Longo
    The neurotransmitter dopamine helps form long-term memories by increasing the production of proteins through a unique signaling pathway.
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    1. Neuroscience

    Neuroscience: Unveiling hidden sources of noise

    Morgan Fitzgerald, Eena Kosik, Bradley Voytek
    Changes in neural activity thought to reflect brain aging may be partly influenced by age-dependent signals ‘leaking’ from the heart.
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    1. Medicine
    2. Neuroscience

    Pain Management: A promising alternative to opioids

    Jie Zhang, Jianguo Cheng
    A complex extracted from the amniotic membrane in humans reduces post-surgical pain in mice by directly inhibiting pain-sensing neurons.
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    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Reprogramming: A perfect recipe for a corticospinal neuron

    Alfonso Aguilera, Marta Nieto
    A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.
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    1. Neuroscience

    Motor Networks: When preparation pays off

    Mark M Churchland
    Computational principles shed light on why movement is preceded by preparatory activity within the neural networks that control muscles.
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    1. Biochemistry and Chemical Biology

    Immunotherapy: The power lies in the glycans

    Luca Unione, Jesús Jiménez-Barbero
    Glycans play an important role in modulating the interactions between natural killer cells and antibodies to fight pathogens and harmful cells.
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    1. Cell Biology

    Kidney Fibrosis: Lock out SIRT4

    Kaiqiang Zhao, Zhongjun Zhou
    The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
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    1. Neuroscience

    Status Epilepticus: Stopping runaway seizures with a chill pill

    Gordon F Buchanan
    The neuropeptide neurotensin can reduce status epilepticus and its associated consequences through induction of therapeutic hypothermia when bound to a molecule that can penetrate the blood-brain barrier.
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    1. Neuroscience

    Sequential Movement: Reaching into the future

    Raeed H Chowdhury
    When carrying out a sequence of movements, humans can plan several steps in advance to make the movement smooth.
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    1. Plant Biology

    Seed Germination: Coping with salt stress

    Xiaoyan Liang, Caifu Jiang
    Salt stress delays seed germination in plants by increasing the hydrolysis of arginine-derived urea.
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