Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.
A study that monitored the expression and function of designer receptors called DREADDs in macaque monkeys for a period of three years demonstrates that they are effective in long-term studies of nonhuman primates.
Differences in the activity of an enzyme called CARM1 influence the timing of blastomere polarization and whether they become part of the embryo or the placenta.
An organoid-based screening platform that allows one-gene-at-a-time knockdown across a whole tissue has been used to identify the genes that regulate closure of the neural tube in humans.
An atlas of all the cell types in the dorsal vagal complex of rodents will help neuroscientists seeking to understand appetite and researchers working to design better drugs for the treatment of obesity and related disorders.
A digital atlas of every cell in a developing marine worm reveals how networks across the body coordinate sensing and movement, and provides insights into the evolution of the nervous system.
