Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Genetics and Genomics

    Neurodevelopmental Disorders: Beyond protein-coding genes

    Anna Lozano-Ureña, Sacri R Ferrón
    A long non-coding RNA called lnc-NR2F1 regulates several neuronal genes, including some involved in autism and intellectual disabilities.
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    1. Biochemistry and Chemical Biology

    Insulin Receptor Binding: From venom peptides to a potential diabetes treatment

    Jiří Jiráček, Lenka Žáková
    Cone snails have evolved a variety of insulin-like molecules that may help with the development of better treatments for diabetes.
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    1. Developmental Biology
    2. Neuroscience

    Embryonic Development: The evolution of hearing and balance

    Forrest P Weghorst, Karina S Cramer
    New genetic tools have allowed researchers to compare how the brainstem auditory and vestibular nuclei develop in embryonic chicks and mice.
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    1. Neuroscience

    Computational Psychiatry: Exploring atypical timescales in the brain

    Leonardo L Gollo
    Identifying activity imbalances in specific brain regions may help to diagnose and treat psychiatric disorders.
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    1. Neuroscience

    Human Intelligence: What single neurons can tell us

    Elaine N Miller, Chet C Sherwood
    IQ scores are correlated with the morphology and activity of certain neurons in the human temporal cortex.
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    1. Microbiology and Infectious Disease

    Tropical Diseases: Can CRISPR help in the fight against parasitic worms?

    Paul McVeigh, Aaron G Maule
    The first reports of CRISPR/Cas9 genome editing in flatworms could usher in a new era of research on these dangerous human parasites.
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    1. Cell Biology

    Autophagy: COPII vesicles and the expansion of the phagophore

    Catherine Rabouille
    A new study has identified the proteins that adapt COPII vesicles to the needs of starving cells.
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    1. Cell Biology
    2. Developmental Biology

    Mechanotransduction: How muscle contraction strengthens tendons

    Nicole O Glenn, Clarissa A Henry
    The force generated by muscles leads to signaling that helps to shape nearby tendon precursor cells.
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    1. Evolutionary Biology
    2. Structural Biology and Molecular Biophysics

    Protein Evolution: Building bigger beta-barrels

    Vikas Nanda
    The range of barrel-shaped proteins found in the outer membrane of certain bacteria evolved through multiple pathways.
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    1. Structural Biology and Molecular Biophysics

    Ion Channels: Solving a specificity mystery

    Sanduo Zheng, Andrew C Kruse
    Differences in the kinetics of G protein activation can explain why only some receptors can activate potassium ion channels called GIRKs.
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