(A) In each block (day) of the experiment, the animal received ethanol injection after the presentation of the stimulus. (B) The change in the body temperature was measured 30, 60, 90, and 120 min after ethanol administration. Initially, the hypothermic effect of ethanol decreased the body temperature of animals. After several training days, however, animals learned to activate a tolerance response upon observing the stimulus, resulting in smaller deviations from the temperature setpoint. If the stimulus was not followed by ethanol injection, as in the first day of extinction (E1), the activation of the conditioned tolerance response resulted in an increase in body temperature. The tolerance response was weakened after several (four) extinction sessions, resulting in increased deviation from the setpoint in the first day of re-acquisition (R1), where presentation of the cue was again followed by ethanol injection.