(A) Insertion of a ferrrodoxin domain (purple) into TOP7 (red). (B) Insertion of one ferrodoxin domain into another. In both cases, two beta strands from each partner (red and purple) are …
(A) Backbone superposition of the crystal structure of ferredoxin-TOP7 (4KYZ, chain A) with the design model. The backbones of the two proteins are nearly identical. (B, C) The core sidechain …
The crystal structure (5CW9) aligns well with the design model over both the helices (A) and the fused beta sheet (B).
Ribbon diagrams are shown on left, the strand connectivity, at the right. The beta strand connectivity is quite different in the designs than in these closest structural matches.
Crystallographic data.