Main text

Zhang S, Zhou M, Shao C, Zhao Y, Liu M, Ni L, Bao Z, Zhang Q, Zhang T, Luo Q, Qu J, Xu Z, Zuo W. 2025. Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial. eLife 13:RP102451. doi: 10.7554/eLife.102451.

Published 4 March 2025

[Details of correction]

The Results section and Table 2 have been corrected. The original manuscript contained two minor inaccuracies that arose during the final consolidation of clinical records. In the Results section (“Safety analysis of REGEND001”), the description of fever-related adverse events has been corrected from “1 grade II” to “2 grade II”. In Table 2 (Adverse events), the value for “Hemoptysis” at 1 M was incorrectly reported as 2 (16.67) and has been corrected to 1 (8.33). These corrections are limited to specific data points and do not affect the overall results, statistical analyses, or conclusions of the study.

[Results: Safety analysis of REGEND001]

[Corrected text:]

Fever is one of the mostly common cell therapy-related AEs (21.4%, 2 grade II, 2 grade I)

[Original text:]

Fever is one of the mostly common cell therapy-related AEs (21.4%, 1 grade II, 2 grade I)

[Table 2:]

[The corrected Table 2 is shown here:]

Table 2. Adverse events*

No. (%) of Patients With Adverse Events
Events0.6 M1 M2 M3.3 M
Any adverse event2 (16.67)3 (25.00)3 (25.00)3 (25.00)
Serious adverse events2 (16.67)01 (8.33)1 (8.33)
Fatal adverse events0000
Adverse events leading to discontinuation0000
Frequent adverse events:
Likely related to Bronchoscopy
 Hemoptysis1 (8.33)1 (8.33)1 (8.33)1 (8.33)
 Fever01 (8.33)2 (16.67)1 (8.33)
 White blood cell counts increased01 (8.33)01 (8.33)
 Productive cough1 (8.33)1 (8.33)00
 Bronchitis1 (8.33)000
Others
 COVID-19003 (25.00)3 (25.00)
 Bronchitis2 (16.67)001 (8.33)
 Hypokalemia1 (8.33)01 (8.33)0

*Shown are adverse events occurred in patients from baseline examination to the end of the study visit. Events are listed in descending order of frequency.

†The frequent adverse events were defined as those with an incidence ≥2 patients, which were ordered by frequency of occurrence here.

[The originally published Table 2 is also shown for reference:]

Table 2. Adverse events*

No. (%) of Patients With Adverse Events
Events0.6 M1 M2 M3.3 M
Any adverse event2 (16.67)3 (25.00)3 (25.00)3 (25.00)
Serious adverse events2 (16.67)01 (8.33)1 (8.33)
Fatal adverse events0000
Adverse events leading to discontinuation0000
Frequent adverse events:
Likely related to Bronchoscopy
 Hemoptysis1 (8.33)2 (16.67)1 (8.33)1 (8.33)
 Fever01 (8.33)2 (16.67)1 (8.33)
 White blood cell counts increased01 (8.33)01 (8.33)
 Productive cough1 (8.33)1 (8.33)00
 Bronchitis1 (8.33)000
Others
 COVID-19003 (25.00)3 (25.00)
 Bronchitis2 (16.67)001 (8.33)
 Hypokalemia1 (8.33)01 (8.33)0

*Shown are adverse events occurred in patients from baseline examination to the end of the study visit. Events are listed in descending order of frequency.

†The frequent adverse events were defined as those with an incidence ≥ 2 patients, which were ordered by frequency of occurrence here.

The article has been corrected accordingly.

Article and author information

Author details

  1. Shiyu Zhang

  2. Min Zhou

  3. Chi Shao

  4. Yu Zhao

  5. Mingzhe Liu

  6. Lei Ni

  7. Zhiyao Bao

  8. Qiurui Zhang

  9. Ting Zhang

  10. Qun Luo

    For correspondence
    luoqunx@163.com
  11. Jieming Qu

    For correspondence
    jmqu0906@163.com
  12. Zuojun Xu

    For correspondence
    xuzj@hotmail.com

Version history

  1. Version of Record published:

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© 2026, Zhang et al.

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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  1. Shiyu Zhang
  2. Min Zhou
  3. Chi Shao
  4. Yu Zhao
  5. Mingzhe Liu
  6. Lei Ni
  7. Zhiyao Bao
  8. Qiurui Zhang
  9. Ting Zhang
  10. Qun Luo
  11. Jieming Qu
  12. Zuojun Xu
  13. Wei Zuo
(2026)
Correction: Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial
eLife 15:e111684.
https://doi.org/10.7554/eLife.111684

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