Stem Cells and Regenerative Medicine

Latest articles

1. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Contribution of Trp63^CreERT2 labeled cells to alveolar regeneration is independent of tuft cells

   Huachao Huang, Yinshan Fang ... Jianwen Que
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   The C. elegans gonadal sheath Sh1 cells extend asymmetrically over a differentiating germ cell population in the proliferative zone

   Xin Li, Noor Singh ... Kacy Lynn Gordon

   As Caenorhabditis elegans adult hermaphrodite germ cells leave the stem cell niche, they associate with a pair of somatic gonad cells that were thought to be symmetrical, but that actually take on dramatically different positions in the organ.
3. 1. Stem Cells and Regenerative Medicine

   Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair

   Justinn Barr, Maria Elena Gentile ... Andrew E Vaughan
4. 1. Genetics and Genomics
   2. Stem Cells and Regenerative Medicine

   Highly efficient generation of isogenic pluripotent stem cell models using prime editing

   Hanqin Li, Oriol Busquets ... Frank Soldner
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming

   Marta Perera, Silas Boye Nissen ... Joshua M Brickman

   The simultaneous expansion of G1 and acceleration of the cell cycle, while ensuring synchronous inheritance of these properties, progressively induces cell identity in differentiation.
6. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Identification of putative enhancer-like elements predicts regulatory networks active in planarian adult stem cells

   Jakke Neiro, Divya Sridhar ... Aziz Aboobaker
7. 1. Stem Cells and Regenerative Medicine

   A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration

   Ana S Brandão, Jorge Borbinha ... Antonio Jacinto

   Zebrafish caudal fin amputation induces an increase in the glycolytic influx that leads to dedifferentiation of osteoblasts and their re-entry in the cell cycle, which is essential for blastema formation and bone regeneration.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy

   Sobhika Agarwala, Keun-Young Kim ... Owen J Tamplin

   Multiple imaging modalities resolved the ultrastructure of single hematopoietic stem cells in their endogenous niche, allowing identification of dopamine beta-hydroxylase positive cells as a functional niche cell type.
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Development: Shining a light on hematopoietic stem cells

   Anne Schmidt

   A combination of light and electron microscopy has revealed further details about the location and interactions of hematopoietic stem and progenitor cells.
10. 1. Stem Cells and Regenerative Medicine

    Generation of functional hepatocytes by forward programming with nuclear receptors

    Rute A Tomaz, Ekaterini D Zacharis ... Ludovic Vallier

    Forward programming of human pluripotent stem cells with a combination of four transcription factors allows the production of functional hepatocytes.