Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration

    Terren K Niethamer, Lillian I Levin ... Edward E Morrisey
    After acute lung injury, the transcription factor Atf3 is essential for regeneration of the capillary endothelium, which is critical for restoring the structure of the lung alveolus.
    1. Stem Cells and Regenerative Medicine

    Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity

    Claudia Dominici, Oscar D. Villarreal ... Stéphane Richard
    1. Stem Cells and Regenerative Medicine

    Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis

    Rachel Warren, Handeng Lyu ... Stijn P De Langhe
    Alveolar type 2 stem cells are actively maintained by Hippo signaling and Taz promotes alveolar epithelial regeneration and the resolution of bleomycin induced pulmonary fibrosis upon inactivation of the Hippo pathway in Alveolar type 2 stem cells.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation

    Rafael Soares Godoy, Nicholas D Cober ... Duncan J Stewart
    Single-cell transcriptomic analysis reveals novel regenerative endothelial cell populations that mediate remarkably rapid and complete microvascular repair in a novel model of acute lung injury induced by endothelial cell ablation.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell transcriptomics of a dynamic cell behavior in murine airways

    Sheldon JJ Kwok, Daniel T Montoro ... Vladimir Vinarsky
    Live imaging of cells in an intact murine tissue combined with single-cell sequencing reveals a unique transcriptional signature of an observed cellular behavior.
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    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    PTH regulates osteogenesis and suppresses adipogenesis through Zfp467 in a feed-forward, PTH1R-cyclic AMP-dependent manner

    Hanghang Liu, Akane Wada ... Clifford J Rosen
    Loss or PTH1R-mediated repression of Zfp467 results in a pathway that increases Pth1r transcription via NFκB1 and thus cellular responsiveness to PTH/PTHrP, ultimately leading to enhanced bone formation.

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Utpal Banerjee
    University of California, Los Angeles, United States
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