Stem Cells and Regenerative Medicine

Latest articles

1. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome

   Georgia Panagiotakos et al.

   The Timothy syndrome mutation in Ca_v1.2 gives rise to defects in neuronal differentiation by preventing a developmental switch in channel splicing and elevating calcium signaling in differentiating cells.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration

   Stephanie L Tsai et al.

   Elucidation of the molecular basis of early wound epidermis dependence during salamander limb regeneration reveals midkine as a key modulator of wound epidermis development and wound-healing resolution.
3. 1. Stem Cells and Regenerative Medicine

   The follicle epithelium in the Drosophila ovary is maintained by a small number of stem cells

   Jocelyne Fadiga, Todd G Nystul

   Just 2-4 follicle stem cells maintain each follicle epithelium in the Drosophila ovary, and they reside within a single ring at the anterior edge of the tissue.
4. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   In vivo single-cell lineage tracing in zebrafish using high-resolution infrared laser-mediated gene induction microscopy

   Sicong He et al.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

   Hessel Honkoop et al.
6. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction

   Shir Toubiana et al.

   Correction of the DNA methyltransferase 3B gene in ICF1 syndrome fails to rescue the abnormal DNA hypomethylation at subtelomeric regions due to accompanied epigenetic abnormalities in these regions.
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration

   Dana Gancz et al.

   Cardiac lymphatic vessels of heterogeneous origins and molecular signatures support cardiac growth and regeneration.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Late developing cardiac lymphatic vasculature supports adult zebrafish heart function and regeneration

   Michael RM Harrison et al.

   Zebrafish develop cardiac lymphatic vessels along coronary arteries and this vasculature supports scar reduction following severe damage to the myocardium.
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes

   Sridhar Selvaraj et al.

   Treatment of human pluripotent stem cell-derived myotubes with a cocktail of small molecules induces their maturation, as shown by gene expression, biochemical and functional assays.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Regeneration: Lymphatic vessels help mend broken hearts

    Catherine Pfefferli, Anna Jaźwińska

    Experiments on zebrafish show that the regeneration of the heart after an injury depends on lymphatic vessels.