Stem Cells and Regenerative Medicine

Latest articles

1. 1. Stem Cells and Regenerative Medicine

   Philosophy of Biology: Towards a classification of stem cells

   Lucie Laplane, Eric Solary

   The occurrence, progression and treatment of cancer may be linked to changes in the nature of stemness.
2. 1. Computational and Systems Biology
   2. Stem Cells and Regenerative Medicine

   Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming

   Mirko Francesconi et al.
3. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Distinct progenitor populations mediate regeneration in the zebrafish lateral line

   Eric D Thomas, David W Raible
4. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Programmed conversion of hypertrophic chondrocytes into osteoblasts and marrow adipocytes within zebrafish bones

   Dion Giovannone et al.

   Cartilage cells transition through a proliferative intermediate to give rise to bone and marrow fat cells in long bones.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   In vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development

   Jia Zhao et al.

   In vivo imaging reveals that gradually increased amount of glucose mediates the heterogeneous functional development of individual β-cells by activating its major downstream calcineurin/NFAT signaling pathway.
6. 1. Genetics and Genomics
   2. Stem Cells and Regenerative Medicine

   The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders

   Cheen Euong Ang et al.

   lnc-Nr2f1, a long non-coding RNA focally deleted in autism patients, directly occupies and regulates neuronal genes.
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Nephron progenitor commitment is a stochastic process influenced by cell migration

   Kynan T Lawlor et al.

   Stochastic cell migration modulates exposure to signals that regulate commitment in the nephron progenitor niche.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling

   Mark E Lush et al.

   Several support cell populations balance progenitor maintenance with differentiation in zebrafish lateral line sensory organs.
9. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Response to comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'

   David J Goldhamer, John B Lees-Shepard

   We respond to concerns expressed by Pacifici and Shore (2019) about our recent paper (Lees-Shepard et al., 2018a).
10. 1. Stem Cells and Regenerative Medicine

    Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass

    Bo Shen et al.

    Integrin a11 is identified as an Osteolectin receptor, revealing a new mechanism for adult skeletal bone maintenance in which Osteolectin/a11b1 signaling promotes bone formation by activating the Wnt pathway.