Stem Cells and Regenerative Medicine

Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis

   Joseph A Bisson, Miriam Gordillo ... Todd Evans

   Differentiation of human pluripotent stem cells mutant for one GATA6 gene can model developmental heart defects seen in some patients with congenital heart disease.
2. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Single-nucleus transcriptomics reveal the cytological mechanism of conjugated linoleic acids in regulating intramuscular fat deposition

   Liyi Wang, Shiqi Liu ... Tizhong Shan

   The cytological mechanism of conjugated linoleic acids regulates fat infiltration in skeletal muscles based on pig models via using single-nucleus transcriptomics.
3. 1. Stem Cells and Regenerative Medicine

   Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration

   Xiexiang Shao, Xingzuan Lin ... Ping Hu
4. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells

   Olivia B Taylor, Nicholas DeGroff ... Andy J Fischer

   Inflammatory S1P signaling is dynamically regulated in chick Müller glia after retinal injury and suppresses Müller glia reprogramming into neuron-like cells.
5. 1. Cancer Biology
   2. Stem Cells and Regenerative Medicine

   Regulation of lung cancer initiation and progression by the stem cell determinant Musashi

   Alison G Barber, Cynthia M Quintero ... Tannishtha Reya

   The stem cell signal Msi2 plays a dual role in lung cancer, acting as a signal that is not only essential for initiation, but also for propagation of the tumor.
6. 1. Stem Cells and Regenerative Medicine

   Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

   Jacob W Klemm, Chloe Van Hazel, Robin E Harris

   A non-apoptotic function of the caspase Dronc is essential to promote tissue repair in response to necrosis via a previously uncharacterized mechanism.
7. 1. Stem Cells and Regenerative Medicine

   Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

   Shiyu Zhang, Min Zhou ... Wei Zuo

   It is safe to transplant autologous P63+ progenitor cells isolated from healthy bronchi to IPF patients for the treatment of IPF, and preliminary efficacy has been demonstrated in some patients.
8. 1. Stem Cells and Regenerative Medicine

   Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation

   Ellen Späth, Svenja C Schüler ... Alessandro Ori
9. 1. Stem Cells and Regenerative Medicine

   Clonal analysis of murine HSC self-renewal and differentiation in native hematopoiesis

   Chenyu You, Zhen Zhang ... Jianlong Sun
10. 1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

    Ana Catarina Costa, Blanca R Murillo ... Monica M Sousa

    Proteomic analyses reveal a distinct protein signature underlying microtubule organization and regenerative asymmetries in sensory neuron axons, supported by an in vitro system replicating key features of sensory neuron biology.