Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation

    Li He, Jiayu Wen, Qi Dai
    PRDM16 directs BMP signaling outcomes by guiding SMAD complex genomic binding to repress neural stem cell proliferation and promote choroid plexus epithelial specification.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cardiac Repair: Aiming for spatial and temporal control of gene expression

    Stanislao Igor Travisano, Ching-Ling Lien
    Bioluminescent imaging is helping researchers better understand the effectiveness of tissue regeneration enhancers delivered to injured heart tissue by different adeno-associated virus vectors.
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    CRISPR-edited DPSCs constitutively expressing BDNF enhance dentin regeneration in injured teeth

    Ji Hyun Kim, Muhammad Irfan ... Seung Chung
    Brain-derived neurotrophic factor/tropomyosin receptor kinase B signaling in promoting the differentiation and dentin-repair capacity of dental stem cells under inflammatory conditions offers a potential clinical strategy for repairing damaged teeth.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

    M Reza Bahranifard, Jessica Chan ... C Ross Ethier
    Magnetically steered mesenchymal stem cells significantly lowered intraocular pressure for 9 months in mice, motivating the translation of this technology for the treatment of glaucoma.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

    Katsuyuki Nishi, Taro Sakamaki ... Masanori Miyanishi
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

    José Antonio Valer, Alexandre Deber ... Francesc Ventura
    PI3Kα inhibitors show promise as therapeutic agents for the treatment of heterotopic ossification.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

    David W Wolfson, Joshua A Hull ... Kenneth D Poss
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration

    Xiexiang Shao, Xingzuan Lin ... Ping Hu
    Tendon regeneration is supported by human CD29+/CD56+ myogenic progenitors through tenogenic differentiation, representing a distinct stem cell population with therapeutic potential.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Changes in neural progenitor lineage constituent during astrocytic differentiation of human iPSCs

    Zongze Li, Lucia Fernandez Cardo ... Meng Li
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Lynne-Marie Postovit
    University of Alberta, Canada
  3. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  4. See more editors