Stem Cells and Regenerative Medicine

Latest articles

1. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes

   Carolina Ortiz-Cordero et al.

   The combined use of NAD+ with ribitol or ribose potentiates the rescue of α-dystroglycan functional glycosylation in FKRP-mutant patient-specific iPSC-derived myotubes, representing potential novel treatments for FKRP muscular dystrophies.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Cystic proliferation of germline stem cells is necessary to reproductive success and normal mating behavior in medaka

   Luisa F Arias Padilla et al.
3. 1. Physics of Living Systems
   2. Stem Cells and Regenerative Medicine

   DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

   Simona Hankeova et al.

   Dual resin casting of multiple lumenized systems followed by microCT allows visualization, digitalization, and quantification of architectural parameters defining the vascular and biliary systems in liver revealing new phenotypes.
4. 1. Stem Cells and Regenerative Medicine

   Heterogeneity of murine periosteum progenitors involved in fracture healing

   Brya G Matthews et al.

   Murine periosteum is highly enriched for osteoprogenitors, many of which express αSMA, but fracture callus chondrocytes are partially derived from other sources.
5. 1. Physics of Living Systems
   2. Stem Cells and Regenerative Medicine

   Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis

   Arne D Hofemeier et al.

   Combining global and local force measurements of reconstituted muscle tissue using a new chamber system that is compatible with high-resolution microscopy shows mechanical homeostasis already within a week.
6. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Regenerative neurogenic response from glia requires insulin-driven neuron-glia communication

   Neale J Harrison et al.

   Neuronal Ia-2 and glial Kon coordinate an injury-response insulin relay that restores glial cell populations and induces neural stem cells from glia, enabling central nervous system regeneration.
7. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Dyshomeostatic modulation of Ca²⁺-activated K⁺ channels in a human neuronal model of KCNQ2 encephalopathy

   Dina Simkin et al.

   An inducedpluripotent stem cell (iPSC)-based model of KCNQ2-associated developmental epileptic encephalopathy suggests that disease is driven by dyshomeostaic neuronal mechanisms that are downstream of loss of M-current.
8. 1. Stem Cells and Regenerative Medicine

   Stem cell transplantation rescued a primary open-angle glaucoma mouse model

   Siqi Xiong et al.

   Stem cell transplantation reduces intraocular pressure and preserves retinal ganglion cell function in a mouse glaucoma model, which could lead to a novel therapy for glaucoma to preserve vision.
9. 1. Stem Cells and Regenerative Medicine

   Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis

   Katherine T Best et al.

   Adult Scleraxis-lineage cells are not required for successful tendon healing but are required for maintenance of tendon homeostasis.
10. 1. Stem Cells and Regenerative Medicine

    Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

    Andrew W DeVilbiss et al.

    A method was developed for the metabolomic analysis of small numbers of flow cytometrically isolated cells from rare cell populations such as hematopoietic stem cells and circulating cancer cells.