Stem Cells and Regenerative Medicine

Latest articles

1. 1. Computational and Systems Biology
   2. Stem Cells and Regenerative Medicine

   Self-assembling manifolds in single-cell RNA sequencing data

   Alexander J Tarashansky et al.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation

   Jelle van den Ameele, Andrea Brand
3. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes

   Takeshi Katsuda et al.

   Human chemically induced liver progenitors (hCLiPs), which are generated from primary human hepatocytes, exhibit the potential to repopulate injured livers of host mice with efficiency > 90%.
4. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human Retina-on-a-Chip platform

   Kevin Achberger et al.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish

   Shuguang Yu, Jie He

   The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.
6. 1. Chromosomes and Gene Expression
   2. Stem Cells and Regenerative Medicine

   TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2

   Rosa María Marión et al.

   Telomeric TRF1 controls the transcriptional programmes of pluripotent stem cells by recruiting PRC2 to pluripotency and differentiation genes by controlling the expression of those gene sites and the binding of TERRA RNAs to them.
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration

   Zhihao Jia et al.

   Inhibition of Polo-like kinase that has been shown to exhibit antitumor effect unexpectedly disrupts muscle stem cell function, leading to developmental and regenerative failures.
8. 1. Stem Cells and Regenerative Medicine

   Skin vasculature and hair follicle cross-talking associated with stem cell activation and tissue homeostasis

   Kefei Nina Li et al.

   Hair follicle epithelium and skin vasculature remodeling are coordinated during quiescence, and their cross-talking is associated with the timing of stem cell activation.
9. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons

   Disi An et al.

   Stem cell-derived motor neurons with differential ALS vulnerability identified proteasome activity as a possible mechanism that explains their differential sensitivity.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Epithelial geometry regulates spindle orientation and progenitor fate during formation of the mammalian epidermis

    Kimberly Box et al.

    Early in mammalian epidermal development, basal epidermal progenitor cells utilize packing and three-dimensional geometry, rather than cortical polarity cues, to inform division orientation and progenitor cell fate.