Stem Cells and Regenerative Medicine

Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Transcriptional heterogeneity and cell cycle regulation as central determinants of primitive endoderm priming

   Marta Perera et al.
2. 1. Stem Cells and Regenerative Medicine

   Generation of functional hepatocytes by forward programming with nuclear receptors

   Rute A Tomaz et al.

   Forward programming of human pluripotent stem cells with a combination of four transcription factors allows the production of functional hepatocytes.
3. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Full spectrum flow cytometry reveals mesenchymal heterogeneity in first trimester placentae and phenotypic convergence in culture, providing insight into the origins of placental mesenchymal stromal cells

   Anna Leabourn Boss et al.

   Full spectrum flow cytometry reveals a high degree of placental mesenchymal cell heterogeneity, which is lost with culture, highlighting the importance of detailed ex vivo phenotyping to optimise the use of these cells in downstream applications.
4. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy

   Sobhika Agarwala et al.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Decoding the activated stem cell phenotype of the neonatally maturing pituitary

   Emma Laporte et al.

   The neonatally maturing pituitary harbors an activated stem cell compartment and shows prominent regenerative capacity, as revealed by single-cell transcriptomic profiling and in vitro (organoid) and in vivo (mouse) exploration.
6. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells

   Daniela Ávila-González et al.

   Interaction of human embryonic stem cells (hESC) with human amniotic epithelial cells (hAEC) confers hESC a pluripotent potential that resembles the anteriorized epiblast, which is predisposed to form the neural ectoderm.
7. 1. Computational and Systems Biology
   2. Stem Cells and Regenerative Medicine

   Cell Culture: Implementing robotics and artificial intelligence

   Sujith Sebastian

   An automated platform for cell culture combines robotics and artificial intelligence to optimize cell culture protocols and reliably produce specific cell types that could be used for regenerative medicine treatments.
8. 1. Stem Cells and Regenerative Medicine

   Comparison of freshly cultured versus cryopreserved mesenchymal stem cells in animal models of inflammation: A pre-clinical systematic review

   Chintan Dave et al.

   Administration of cryopreserved as compared freshly cultured MSCs do not appear to negatively impact measures of in vivo efficacy or in vitro potency in animal models of inflammation.
9. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Functional requirements for a Samd14-capping protein complex in stress erythropoiesis

   Suhita Ray et al.

   Genetic complementation approaches in a mouse model of anemia reveals new protein interactions which aid cell survival and promote sensing of environmental cues.
10. 1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Generation of vascularized brain organoids to study neurovascular interactions

    Xin-Yao Sun et al.

    A vessel and brain fusion organoid model provides a platform for the study of interactions between neuronal and non-neuronal components during brain development and functioning.