Stem Cells and Regenerative Medicine

Latest articles

1. 1. Stem Cells and Regenerative Medicine

   Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the PPARγ-homolog Eip75B in Drosophila

   Lisa Zipper et al.
2. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Activation of a neural stem cell transcriptional program in parenchymal astrocytes

   Jens P Magnusson et al.
3. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche

   Kacy L Gordon et al.
4. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Generation of inner ear hair cells by direct lineage conversion of primary somatic cells

   Louise Menendez et al.

   Direct reprogramming of somatic cells to an inner ear sensory hair cell-like state provides an experimental platform to identify causes and treatments for hair cell loss and hearing deficits.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Tgfβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration

   Deepak A Kaji et al.

   TGFß signaling regulates migration of tenogenic cells from Scx- and non-Scx lineages and is required for functional regeneration after neonatal tendon injury.
6. 1. Stem Cells and Regenerative Medicine

   Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

   Hyunah Lee et al.

   Sequential introduction of transcription factors enables large-scale generation of induced motor neurons (iMNs) from human somatic cells, and transplantation of iMNs exhibit therapeutic effects in spinal cord injury model.
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in Drosophila

   Robin E Harris et al.

   The reduced ability of Drosophila imaginal discs to regenerate as they mature can be explained by the silencing of damage-responsive enhancers that regulate expression of genes required for regeneration.
8. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes

   Tamar Licht et al.

   Neural stem cells in the dentate gyrus have unique cytoplasmic processes that promote privileged access to circulating factors by a unique contact point with an endothelial cell.
9. 1. Stem Cells and Regenerative Medicine

   Tgfb3 collaborates with PP2A and notch signaling pathways to inhibit retina regeneration

   Mi-Sun Lee et al.

   Tgfb3 inhibits Muller glial cell reprogramming and drives Muller cell quiescence in the injured zebrafish retina, thereby inhibiting retina regeneration.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Chromatin accessibility dynamics and single cell RNA-Seq reveal new regulators of regeneration in neural progenitors

    Anneke Dixie Kakebeen et al.

    Regenerating neural progenitors of the Xenopus tropicalis tail prioritize differentiation to motor neuron types earlier than proliferation, a decision partly regulated by the transcription factors Pbx3 and Meis1.