Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

    David W Wolfson, Joshua A Hull ... Kenneth D Poss
    Bioluminescence imaging in live mice was used to assess the abilities of systemically introduced adeno-associated viral capsids containing enhancer regulatory sequences to target transgene expression to myocardial injuries.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Endothelin B receptor inhibition rescues aging-dependent neuronal regenerative decline

    Rui Feng, Sarah F Rosen ... Valeria Cavalli
    Inhibition of the endothelin B receptor (ETBR) with FDA-approved Bosentan enhances axon regeneration and reverses age-related decline, revealing a promising therapeutic target for improving nerve repair in older individuals.
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

    Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Stem Cells and Regenerative Medicine

    Chromatin activity of IκBα mediates the exit from naïve pluripotency

    Luis G Palma, Daniel Álvarez-Villanueva ... Anna Bigas
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Alteration of long- and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

    Katsuyuki Nishi, Taro Sakamaki ... Masanori Miyanishi
    Self-renewal heterogeneity causes myeloid skewing.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Efficient Generation of Expandable Dorsal Forebrain Neural Rosette Stem Cell Lines

    Signe Emilie Dannulat Frazier, Kristian Honnens de Lichtenberg ... J Carlos Villaescusa
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

    Abdulkadir Ozkan, Hari K Padmanabhan ... Jeffrey D Macklis
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians

    Ryan A McCubbin, Mohammad A Auwal ... Ricardo M Zayas
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Stabilisation of HIF signalling extends epicardial activation and neonatal heart regeneration

    Elisabetta Gamen, Eleonor L Price ... Paul R Riley
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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Highlights

    1. Stem Cells and Regenerative Medicine

    Encouraging cartilage production

    H Scott Stadler
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Mending broken hearts

    Catherine Pfefferli, Anna Jaźwińska
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    A better model of the retina

    Milica Radisic

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Lynne-Marie Postovit
    University of Alberta, Canada
  3. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  4. See more editors