Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife publishes research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Stem Cells and Regenerative Medicine

    Mechanical stimulation promotes enthesis injury repair by mobilizing Prrx1+ cells via ciliary TGF-β signaling

    Han Xiao et al.
    The proper mechanical stimulus could promote the migration of Prrx1+ cells to the injury site to enhance enthesis injury repair.
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells

    Boyang Ren et al.
    Hematopoietic progenitor cells employ CD47 to engage thymic portal endothelial signal regulatory protein alpha for their transendothelial migration and thymic homing.
    1. Stem Cells and Regenerative Medicine

    Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the Drosophila testis niche

    Leah J Greenspan et al.
    In the adult Drosophila testis, normally quiescent niche cells can be forced to re-enter the cell cycle and give rise to new stem cells in response to epidermal growth factor receptor signaling.
    1. Genetics and Genomics
    2. Stem Cells and Regenerative Medicine

    Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

    Diljeet Gill et al.
    Transiently reprogramming human fibroblasts up to the maturation phase rejuvenates cells according to several aging markers whilst enabling them to return to their original identity.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse

    Alexandre Grimaldi et al.
    Combined lineage-tracing strategies, single-cell transcriptomic methods and in situ analyses identified mesodermal bipotent progenitors during craniofacial myogenesis that give rise to myogenic and connective tissues, thus redefining the lineage and evolutionary relationships between muscle and associated stroma.
    1. Cancer Biology
    2. Stem Cells and Regenerative Medicine

    Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity

    Chie Sugimoto et al.
    Mucosal-associated invariant T cells, an emerging member of the innate-like T cells abundant in humans bridging the innate and the adaptive immunity, could be exploited as a novel tool for cancer immunotherapy through cell reprogramming.

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Marianne E Bronner
    Marianne E Bronner
    California Institute of Technology, United States
  3. Edward Morrisey
    University of Pennsylvania, United States
  4. See more editors