Stem Cells and Regenerative Medicine

Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation

   Li He, Jiayu Wen, Qi Dai

   PRDM16 directs BMP signaling outcomes by guiding SMAD complex genomic binding to repress neural stem cell proliferation and promote choroid plexus epithelial specification.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Cardiac Repair: Aiming for spatial and temporal control of gene expression

   Stanislao Igor Travisano, Ching-Ling Lien

   Bioluminescent imaging is helping researchers better understand the effectiveness of tissue regeneration enhancers delivered to injured heart tissue by different adeno-associated virus vectors.
3. 1. Stem Cells and Regenerative Medicine

   CRISPR-edited DPSCs constitutively expressing BDNF enhance dentin regeneration in injured teeth

   Ji Hyun Kim, Muhammad Irfan ... Seung Chung

   Brain-derived neurotrophic factor/tropomyosin receptor kinase B signaling in promoting the differentiation and dentin-repair capacity of dental stem cells under inflammatory conditions offers a potential clinical strategy for repairing damaged teeth.
4. 1. Medicine
   2. Stem Cells and Regenerative Medicine

   Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

   M Reza Bahranifard, Jessica Chan ... C Ross Ethier

   Magnetically steered mesenchymal stem cells significantly lowered intraocular pressure for 9 months in mice, motivating the translation of this technology for the treatment of glaucoma.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

   Katsuyuki Nishi, Taro Sakamaki ... Masanori Miyanishi
6. 1. Stem Cells and Regenerative Medicine

   Glycogen Engineering Improves the Starvation Resistance of Mesenchymal stem cells and their Therapeutic Efficacy in Pulmonary Fibrosis

   Yongyue Xu, Mamatali Rahman ... Qiong Wu
7. 1. Stem Cells and Regenerative Medicine

   PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

   José Antonio Valer, Alexandre Deber ... Francesc Ventura

   PI3Kα inhibitors show promise as therapeutic agents for the treatment of heterotopic ossification.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

   David W Wolfson, Joshua A Hull ... Kenneth D Poss
9. 1. Stem Cells and Regenerative Medicine

   Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration

   Xiexiang Shao, Xingzuan Lin ... Ping Hu

   Tendon regeneration is supported by human CD29+/CD56+ myogenic progenitors through tenogenic differentiation, representing a distinct stem cell population with therapeutic potential.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Changes in neural progenitor lineage constituent during astrocytic differentiation of human iPSCs

    Zongze Li, Lucia Fernandez Cardo ... Meng Li