Stem Cells and Regenerative Medicine

Latest articles

1. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

   Kevin Achberger et al.

   A microphysiological system (retina-on-a-chip) shows the potential to promote drug development and provide new insights into the underlying pathology of retinal diseases.
2. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Tissue Engineering: Building a better model of the retina

   Milica Radisic

   Researchers have combined organ-on-a-chip engineering with the benefits of organoids to make improved models of the human retina.
3. 1. Stem Cells and Regenerative Medicine

   Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle

   Sumiaki Fukuda et al.

   Proliferating muscle stem cells in overloaded muscle require special molecular mechanisms that differ from well-known myogenic differentiation model.
4. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Human perivascular stem cell-derived extracellular vesicles mediate bone repair

   Jiajia Xu et al.

   Perivascular extracellular vesicles induce bone repair, and do so via tetraspanin binding to recipient skeletal progenitor cells.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation

   Jelle van den Ameele, Andrea H Brand

   Mitochondrial dysfunction in neural stem cells and brain tumour cells decreases proliferation and affects the generation of neuronal diversity and tumour heterogeneity.
6. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells

   Isabelle Maria Blomfield et al.
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   A distinct transition from cell growth to physiological homeostasis in the tendon

   Mor Grinstein et al.
8. 1. Computational and Systems Biology
   2. Stem Cells and Regenerative Medicine

   Self-assembling manifolds in single-cell RNA sequencing data

   Alexander J Tarashansky et al.
9. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes

   Takeshi Katsuda et al.

   Human chemically induced liver progenitors (hCLiPs), which are generated from primary human hepatocytes, exhibit the potential to repopulate injured livers of host mice with efficiency > 90%.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish

    Shuguang Yu, Jie He

    The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.