Stem Cells and Regenerative Medicine

Latest articles

1. 1. Cell Biology
   2. Developmental Biology
   3. Stem Cells and Regenerative Medicine

   ZMYND10 functions in a chaperone relay during axonemal dynein assembly

   Girish R Mali et al.

   Chaperoning defects in axonemal dynein subunits trigger proteostatic clearance of dynein motors opening up the possibility of trialling proteostasis modulators to treat the motile ciliopathy primary ciliary dyskinesia (PCD).
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Embryonic hematopoiesis modulates the inflammatory response and larval hematopoiesis in Drosophila

   Wael Bazzi et al.

   Distinct hematopoietic waves interact via transcriptional cascades specific to embryonic hemocytes to ensure the proper immune response in Drosophila.​.
3. 1. Microbiology and Infectious Disease
   2. Stem Cells and Regenerative Medicine

   Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni

   Bo Wang et al.

   Distinct stem cell populations drive larval, somatic, and germline development of the human parasitic flatworm, Schistosoma mansoni.
4. 1. Computational and Systems Biology
   2. Developmental Biology
   3. Stem Cells and Regenerative Medicine

   Vertex sliding drives intercalation by radial coupling of adhesion and actomyosin networks during Drosophila germband extension

   Timothy E Vanderleest et al.

   Tricellular vertices possess sliding behaviors that harness radial forces and drive cell shape changes and intercalation in an epithelial tissue.
5. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the Drosophila testis

   Salvador C Herrera, Erika A Bach
6. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice

   Kerstin Schmidt et al.

   The H3K4 methyltransferase Setd1b is intrinsically required for hematopoietic stem and progenitor cell homeostasis and regulates lineage specification in mice.
7. 1. Cell Biology
   2. Developmental Biology
   3. Stem Cells and Regenerative Medicine

   Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

   Kara L McKinley et al.

   The process of cytokinesis can allow cell lineages to intermix in mammalian epithelia, and cellular aspect ratio is a critical modulator of this behavior.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   TALE factors use two distinct functional modes to control an essential zebrafish gene expression program

   Franck Ladam et al.

   TALE transcription factors bind different genomic motifs and function together with different protein partners at different stages of zebrafish embryogenesis.
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity

   Sonia Alonso-Martin et al.

   A set of ex vivo and in vivo experiments, including genetic ablation and regeneration studies, identify a key regulatory function of SOXF factors in muscle stem cells in mice.
10. 1. Cancer Biology
    2. Stem Cells and Regenerative Medicine

    Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes

    Joan Comenge et al.

    Combined cell labelling with a bi-cistronic reporter-gene vector and gold nanorods enables short- and long-term cell tracking in vivo via multimodal imaging (multispectral optoacoustic tomography, bioluminescence, fluorescence) with high spatial resolution.