Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine
    2. Stem Cells and Regenerative Medicine

    A titin missense variant drives atrial electrical remodeling and is associated with atrial fibrillation

    Mahmud Arif Pavel, Hanna Chen ... Dawood Darbar
    Genetic and electrophysiological studies uncover a mechanism linking a TTN missense variant to atrial fibrillation by coupling titin with potassium channel remodeling, revealing FHL2 as a modulator and therapeutic target.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Efficient transduction of pancreas tissue slices with genetically encoded calcium integrators

    Charles S Lazimi, Austin E Stis ... Edward A Phelps
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of osteoarthritis

    Nedaa Al-Jezani, Asmaa Affan ... Roman J Krawetz
    CD47Hi synovial mesenchymal stem cells are identified as a functionally distinct sub-population that regenerates articular cartilage and reduces osteoarthritis severity in a preclinical joint injury model.
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

    Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter
    Functional analyses showcase that in the absence of IL-27, hematopoietic stem and progenitor cells are more likely to become monocytes during toxoplasmosis, making them less responsive after infection.
    1. Stem Cells and Regenerative Medicine

    Glycogen engineering improves the starvation resistance of mesenchymal stem cells and their therapeutic efficacy in pulmonary fibrosis

    Yongyue Xu, Mamatali Rahman ... Qiong Wu
    Glycogen engineering strategies of mammalian cells were developed, which improved the survival of mesenchymal stem cells post-implantation and their therapeutic efficacy in pulmonary fibrosis model.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Genetics and Genomics
    2. Stem Cells and Regenerative Medicine

    Joint profiling of cell morphology and gene expression during in vitro neurodevelopment

    Adithi Sundaresh, Dimitri Meistermann ... Helena Kilpinen
    Molecular and morphological profiles of developing neurons in vitro uncover the cellular dynamics of human neurodevelopment and related disease.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians

    Ryan A McCubbin, Mohammad A Auwal ... Ricardo M Zayas
    A conserved POU4-dependent developmental program underlies mechanosensory neuron regeneration in adult planarians.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Early exercise disrupts a pro-repair extracellular matrix program during zebrafish fin regeneration

    Victor M Lewis, Rafael A Fernandez ... Kryn Stankunas
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  3. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  4. See more editors