Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Stem Cells and Regenerative Medicine

    Dynamic tracking of native precursors in adult mice

    Suying Liu, Sarah E Adams ... Peter Kurre
    A revised analytical framework grounded in the principle of binomial distribution captures the full clonality and dynamic shifts of hematopoiesis throughout ontogeny.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model of Parkinson’s disease

    Desirée Böck, Maria Wilhelm ... Gerald Schwank
    Revised
    Reviewed Preprint v2
    Updated
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

    Ana C Costa, Blanca R Murillo ... Monica M Sousa
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Modeling corticotroph deficiency with pituitary organoids supports the functional role of NFKB2 in human pituitary differentiation

    Thi Thom Mac, Teddy Fauquier ... Thierry Brue
    Pituitary organoids help identify NFKB2 as a new actor during pituitary development, and mutations of this gene as the cause for pituitary deficit observed in patients with DAVID syndrome.
    1. Stem Cells and Regenerative Medicine

    The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation

    Syeda Nayab Fatima Abidi, Sara Chan ... Christian W Siebel
    Inhibition of Notch signaling through the Jag2 ligand, blocks homeostatic sebocyte differentiation, and pushes the cells to a progenitor fate, in a reversible manner.
    1. Stem Cells and Regenerative Medicine

    Switching of RNA splicing regulators in immature neuroblasts during adult neurogenesis

    Corentin Bernou, Marc-André Mouthon ... François Dominique Boussin
    Characterization of an abundant clonogenic and multipotent population of immature neuroblasts, at the transition between transient-amplifying progenitor (TAP) neuroblasts and migratory neuroblasts, reversibly engaged in neuronal differentiation.
    1. Stem Cells and Regenerative Medicine

    Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

    Ryosuke Isotani, Masaki Igarashi ... Toshimasa Yamauchi
    Revised
    Reviewed Preprint v3
    Updated

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Utpal Banerjee
    University of California, Los Angeles, United States
  3. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  4. See more editors