Stem Cells and Regenerative Medicine

Latest articles

1. 1. Stem Cells and Regenerative Medicine

   Endometrial cells with high ALDH activity contribute to uterine development and regeneration

   Suni Tang, Anna Catherine Unser ... Diana Monsivais
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

   Roya E Huang, Giridhar M Anand ... Sharad Ramanathan

   A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure.
3. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Patient-specific midbrain organoids with CRISPR correction recapitulate neuronopathic Gaucher disease phenotypes and enable evaluation of novel therapies

   Yi Lin, Benjamin Liou ... Ying Sun

   Human midbrain organoids provide a foundation for the development of patient-specific preclinical models to support personalized therapeutic approaches and enable evaluation of disease mechanisms and therapeutic strategies in human context.
4. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Adrenomedullin restores the human cortical interneurons migration defects induced by hypoxia

   Alyssa Puno, Wojciech P Michno ... Anca M Pasca

   Exposure of human cortical interneurons to hypoxia leads to decreased migration, a process that is likely altered in preterm infants and contributes to the increased risk for neurodevelopmental problems.
5. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Human adherent cortical organoids in a multi-well format

   Mark van der Kroeg, Sakshi Bansal ... Femke MS de Vrij

   Human stem cell-derived adherent cortical organoids in 384-well plates provide a reproducible, long-term cortical organoid platform with neurons, glia, and robust network activity, enabling scalable disease modeling and therapeutic screening.
6. 1. Stem Cells and Regenerative Medicine

   Synergistic Inhibition of Notch Signaling and Forced Cell Cycle Re-entry Drive Müller Glia Reprogramming in Uninjured Mouse Retina

   Baoshan Liao, Chengshang Lyu ... Wenjun Xiong
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   A developmentally regulated long-range enhancer-promoter contact mediates human neural development

   Devin Bready, Shuai Wang ... Dimitris G Placantonakis
8. 1. Stem Cells and Regenerative Medicine

   Rejuvenation-Responsive and Senolytic-Sensitive Muscle Stem Cells Unveiled by CD200 and CD63 in Geriatric Muscle

   Ye Lynne Kim, Young-Woo Jo ... Young-Yun Kong
9. 1. Stem Cells and Regenerative Medicine

   Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation

   Ellen Späth, Svenja C Schüler ... Alessandro Ori
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during mouse skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen

    Branched actin cytoskeleton is critical for myoblast fusion during mouse skeletal muscle regeneration.