Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Stem Cells and Regenerative Medicine

    PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

    José Antonio Valer, Alexandre Deber ... Francesc Ventura
    PI3Kα inhibitors show promise as therapeutic agents for the treatment of heterotopic ossification.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

    David W Wolfson, Joshua A Hull ... Kenneth D Poss
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Stem Cells and Regenerative Medicine

    CRISPR-Edited DPSCs, Constitutively Expressing BDNF Enhance Dentin Regeneration in Injured Teeth

    Ji Hyun Kim, Muhammad Irfan ... Seung Chung
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Stem Cells and Regenerative Medicine

    Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration

    Xiexiang Shao, Xingzuan Lin ... Ping Hu
    Tendon regeneration is supported by human CD29+/CD56+ myogenic progenitors through tenogenic differentiation, representing a distinct stem cell population with therapeutic potential.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Changes in neural progenitor lineage constituent during astrocytic differentiation of human iPSCs

    Zongze Li, Lucia Fernandez Cardo ... Meng Li
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

    M Reza Bahrani Fard, Jessica Chan ... C Ross Ethier
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

    Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Master control genes in the regeneration of rod photoreceptors from endogenous progenitor cells in zebrafish retina

    Eyad Shihabeddin, Abirami Santhanam ... John O’Brien
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Simultaneous cyclin D1 overexpression and p27kip1 knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina

    Zhifei Wu, Baoshan Liao ... Wenjun Xiong
    A novel strategy is described for stimulating a large number of Müller glia to proliferate in mice by manipulating cell cycle components without a damage stimulus.

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Lynne-Marie Postovit
    University of Alberta, Canada
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors