Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Stem Cells and Regenerative Medicine

    Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts

    Tino Stauber, Greta Moschini ... Jess G Snedeker
    IL-6 signaling drives fibroblast activation in tendinopathy, emerging as a promising therapeutic target for these increasingly prevalent and costly tendon conditions.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia

    Takuma Nohara, Junichi Kumamoto ... Ken Natsuga
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis

    Joseph A Bisson, Miriam Gordillo ... Todd Evans
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

    Ruben Sebastian-Perez, Shoma Nakagawa ... Maria Pia Cosma
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells

    Olivia Taylor, Nick DeGroff ... Andy J Fischer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

    Ana C Costa, Blanca R Murillo ... Monica M Sousa
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

    Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

    Shiyu Zhang, Min Zhou ... Wei Zuo
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Chromatin activity of IκBα mediates the exit from naïve pluripotency

    Luis G Palma, Daniel Álvarez-Villanueva ... Anna Bigas
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
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Highlights

    1. Stem Cells and Regenerative Medicine

    Encouraging cartilage production

    H Scott Stadler
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Mending broken hearts

    Catherine Pfefferli, Anna Jaźwińska
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    A better model of the retina

    Milica Radisic

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Lynne-Marie Postovit
    University of Alberta, Canada
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors