Stem Cells and Regenerative Medicine

Latest articles

1. 1. Stem Cells and Regenerative Medicine

   Regeneration: How the liver keeps itself in shape

   Stephanie May, Thomas G Bird

   After fasting, hepatocytes proliferate to help the liver grow back to its original size.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Efficient generation of marmoset primordial germ cell-like cells using induced pluripotent stem cells

   Yasunari Seita, Keren Cheng ... Kotaro Sasaki
3. 1. Stem Cells and Regenerative Medicine

   Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver

   Abby Sarkar, Yinhua Jin ... Roel Nusse

   Hepatocytes proliferate to maintain a constant liver-to-body mass ratio during intermittent fasting.
4. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Differential chondrogenic differentiation between iPSC derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

   Nazir M Khan, Martha Elena Diaz-Hernandez ... Hicham Drissi

   The iPSCs derived from OA cartilage showed memory of disease which affect its chondrogenic potential and regulation at epigenetic and metabolic level may be used to control the regenerative potential of these iPSCs.
5. 1. Stem Cells and Regenerative Medicine

   Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype

   Antonion Korcari, Anne EC Nichols ... Alayna E Loiselle
6. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene

   Zhichao Zheng, Lihong Wu ... Janak L Pathak

   Mir155 showed a catabolic effect on osteogenesis and bone mass phenotype via interaction with the S1pr1 gene, suggesting inhibition of Mir155 as a potential approach to bone regeneration and bone defect healing.
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Germline/soma distinction in Drosophila embryos requires regulators of zygotic genome activation

   Megan M Colonnetta, Paul Schedl, Girish Deshpande

   Components of zygotic genome activation, Zelda and CLAMP, contribute to the proper specification of primordial germ cells in Drosophila embryos.
8. 1. Stem Cells and Regenerative Medicine

   The mini-IDLE 3D biomimetic culture assay enables interrogation of mechanisms governing muscle stem cell quiescence and niche repopulation

   Erik Jacques, Yinni Kuang ... Penney M Gilbert
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

   Amrita A Iyer, Ishwar Hosamani ... Andrew K Groves

   Cells of the mammalian cochlea can be reprogrammed to produce mechanosensory hair cells, but epigenetic changes in the cochlea make this process less efficient with age.
10. 1. Stem Cells and Regenerative Medicine

    High-resolution imaging of the osteogenic and angiogenic interface at the site of murine cranial bone defect repair via multiphoton microscopy

    Kevin Schilling, Yuankn Zhai ... Xinping Zhang

    High-resolution multiphoton microscopy reveals coupling of blood vessel subtype with expanding osteoblasts at the bone regeneration interface, further highlighting the heterogeneity of oxygen microenvironment and its impact on cellular energy metabolism of bone and vessel forming cells.