Stem Cells and Regenerative Medicine

Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Canonical Wnt signaling and the regulation of divergent mesenchymal Fgf8 expression in Axolotl limb development and regeneration

   Giacomo Leon Glotzer et al.
2. 1. Stem Cells and Regenerative Medicine

   GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

   Rafael Jesus Fernandez III et al.
3. 1. Stem Cells and Regenerative Medicine

   Mechanical stimulation promotes enthesis injury repair by mobilizing Prrx1⁺ cells via ciliary TGF-β signaling

   Han Xiao et al.

   The proper mechanical stimulus could promote the migration of Prrx1⁺ cells to the injury site to enhance enthesis injury repair.
4. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson's disease

   Weizhao Chen et al.
5. 1. Immunology and Inflammation
   2. Stem Cells and Regenerative Medicine

   Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells

   Boyang Ren et al.

   Hematopoietic progenitor cells employ CD47 to engage thymic portal endothelial signal regulatory protein alpha for their transendothelial migration and thymic homing.
6. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Generation of vascularized brain organoids to study neurovascular interactions

   Xin-Yao Sun et al.
7. 1. Stem Cells and Regenerative Medicine

   Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the Drosophila testis niche

   Leah J Greenspan et al.

   In the adult Drosophila testis, normally quiescent niche cells can be forced to re-enter the cell cycle and give rise to new stem cells in response to epidermal growth factor receptor signaling.
8. 1. Genetics and Genomics
   2. Stem Cells and Regenerative Medicine

   Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

   Diljeet Gill et al.

   Transiently reprogramming human fibroblasts up to the maturation phase rejuvenates cells according to several aging markers whilst enabling them to return to their original identity.
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse

   Alexandre Grimaldi et al.

   Combined lineage-tracing strategies, single-cell transcriptomic methods and in situ analyses identified mesodermal bipotent progenitors during craniofacial myogenesis that give rise to myogenic and connective tissues, thus redefining the lineage and evolutionary relationships between muscle and associated stroma.
10. 1. Cancer Biology
    2. Stem Cells and Regenerative Medicine

    Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity

    Chie Sugimoto et al.

    Mucosal-associated invariant T cells, an emerging member of the innate-like T cells abundant in humans bridging the innate and the adaptive immunity, could be exploited as a novel tool for cancer immunotherapy through cell reprogramming.