Stem Cells and Regenerative Medicine

Latest articles

1. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Generation of vascularized brain organoids to study neurovascular interactions

   Xin-Yao Sun et al.

   A vessel and brain fusion organoid model provides a platform for the study of interactions between neuronal and non-neuronal components during brain development and functioning.
2. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Brain Organoids: Getting the right cells

   Bilal Cakir, In-Hyun Park

   Fusing brain organoids with blood vessel organoids leads to the incorporation of non-neural endothelial cells and microglia into the brain organoids.
3. 1. Computational and Systems Biology
   2. Stem Cells and Regenerative Medicine

   Robotic search for optimal cell culture in regenerative medicine

   Genki N Kanda et al.

   Robotic AI system automated discovery of optimum cell culture protocol, a most experience-dependent process in regenerative medicine.
4. 1. Stem Cells and Regenerative Medicine

   Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin

   Jianhua Zhang et al.

   Investigation of defined extracellular matrix proteins in differentiation of human pluripotent stem cells to cardiomyocytes reveals fibronectin, in addition to soluble factors, is required for cardiogenesis.
5. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson’s disease

   Weizhao Chen et al.

   Repressing astroglial PTBP1 by shRNA or antisense oligonucleotide fails to convert astrocyte to neuron including dopaminergic neuron in a 6-OHDA mouse model of PD.
6. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Brain Repair: Gatekeeping astrocyte identity

   Alexis Cooper, Benedikt Berninger

   New findings cast doubt on whether suppressing the RNA-binding protein PTBP1 can force astrocytes to become dopaminergic neurons.
7. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Functional requirements for a Samd14-capping protein complex in stress erythropoiesis

   Suhita Ray et al.
8. 1. Stem Cells and Regenerative Medicine

   GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

   Rafael Jesus Fernandez et al.

   Telomere dysfunction in iPSC-derived type II alveolar epithelial cells causes senescence and gene expression changes including Wnt-related changes that GSK3 inhibition can rescue, providing insight into pulmonary fibrosis pathogenesis.
9. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Chondroitin sulfate proteoglycan 4,6 sulfation regulates sympathetic nerve regeneration after myocardial infarction

   Matthew R Blake et al.

   4,6-Sulfation of chondroitin sulfate proteoglycans prevents sympathetic nerve regeneration into the infarct after myocardial ischemia/reperfusion, and reducing this sulfation promotes nerve regeneration and decreases arrhythmia susceptibility.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Decoding the activated stem cell phenotype of the neonatally maturing pituitary

    Emma Laporte et al.