Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine

eLife reviews research on stem cell function, organogenesis, and tissue regeneration. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Single-nucleus transcriptomics reveal the cytological mechanism of conjugated linoleic acids in regulating intramuscular fat deposition

    Liyi Wang, Shiqi Liu ... Tizhong Shan
    The cytological mechanism of conjugated linoleic acids regulates fat infiltration in skeletal muscles based on pig models via using single-nucleus transcriptomics.
    1. Stem Cells and Regenerative Medicine

    Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration

    Xiexiang Shao, Xingzuan Lin ... Ping Hu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells

    Olivia B Taylor, Nicholas DeGroff ... Andy J Fischer
    Inflammatory S1P signaling is dynamically regulated in chick Müller glia after retinal injury and suppresses Müller glia reprogramming into neuron-like cells.
    1. Cancer Biology
    2. Stem Cells and Regenerative Medicine

    Regulation of lung cancer initiation and progression by the stem cell determinant Musashi

    Alison G Barber, Cynthia M Quintero ... Tannishtha Reya
    The stem cell signal Msi2 plays a dual role in lung cancer, acting as a signal that is not only essential for initiation, but also for propagation of the tumor.
    1. Stem Cells and Regenerative Medicine

    Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

    Jacob W Klemm, Chloe Van Hazel, Robin E Harris
    A non-apoptotic function of the caspase Dronc is essential to promote tissue repair in response to necrosis via a previously uncharacterized mechanism.
    1. Stem Cells and Regenerative Medicine

    Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

    Shiyu Zhang, Min Zhou ... Wei Zuo
    It is safe to transplant autologous P63+ progenitor cells isolated from healthy bronchi to IPF patients for the treatment of IPF, and preliminary efficacy has been demonstrated in some patients.
    1. Stem Cells and Regenerative Medicine

    Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation

    Ellen Späth, Svenja C Schüler ... Alessandro Ori
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Clonal analysis of murine HSC self-renewal and differentiation in native hematopoiesis

    Chenyu You, Zhen Zhang ... Jianlong Sun
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

    Ana Catarina Costa, Blanca R Murillo ... Monica M Sousa
    Proteomic analyses reveal a distinct protein signature underlying microtubule organization and regenerative asymmetries in sensory neuron axons, supported by an in vitro system replicating key features of sensory neuron biology.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

    Joshua G Medina-Feliciano, Griselle Valentín-Tirado ... José E García-Arrarás
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Lynne-Marie Postovit
    University of Alberta, Canada
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors