Stem Cells and Regenerative Medicine

Latest articles

1. 1. Stem Cells and Regenerative Medicine

   Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis

   Katherine T Best et al.
2. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

   Laura J Wagstaff et al.

   In vivo experiments on transgenic mice, and cell culture studies, establish Schwann cell c-Jun as a central regulator of peripheral nerve repair, and repair failure, during aging and chronic denervation.
3. 1. Cancer Biology
   2. Stem Cells and Regenerative Medicine

   Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium

   Madeline Sandoval et al.

   Skin epithelium can tolerate oncogene-expressing clones through a novel cellular mechanism of inter-clonal competition between renewing progenitors along the clone's edge and differentiating progenitors within the clone's core.
4. 1. Stem Cells and Regenerative Medicine

   Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

   Andrew W DeVilbiss et al.
5. 1. Physics of Living Systems
   2. Stem Cells and Regenerative Medicine

   Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis

   Arne D Hofemeier et al.
6. 1. Stem Cells and Regenerative Medicine

   Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells

   John P Russell et al.

   Stem cells of the pituitary gland contribute to organ growth cell non-autonomously by promoting proliferation of committed progenitors through WNT ligand secretion.
7. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory disease

   Ana J Caetano et al.

   Single cell transcriptomic analysis provides a reference map for human oral muscosa in health and disease and a framework for the development of new therapeutic strategies.
8. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells

   Diana Gumber et al.

   Selective activation of FZD7 signaling with an engineered WNT mimetic promotes early developmental programs, including endodermal lineage specification, in human pluripotent stem cells.
9. 1. Stem Cells and Regenerative Medicine

   Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes

   Noemi Rives-Quinto et al.

   Silencing of stem cell identity genes during progenitor commitment ensures that intermediate progenitors robustly commit to generate differentiated cell types rather than abnormal stem-cell-like cells during indirect neurogenesis.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures

    Kyaw Thu Minn et al.

    Micropatterned differentiation of human ESCs generates gastrulation cell types – germ layers, extraembryonic, and primordial germ cells with primate characteristics – that show conserved sorting behaviors when dissociated and reseeded as single-cell mixture.