Stem Cells and Regenerative Medicine

Latest articles

1. 1. Genetics and Genomics
   2. Stem Cells and Regenerative Medicine

   Cell-type diversity and regionalized gene expression in the planarian intestine

   David J Forsthoefel et al.

   Application of laser-capture microdissection to planarian intestinal tissue provides a new tool for analysis of tissue-specific gene expression in flatworms, and a new resource to advance investigations of gastrointestinal regeneration.
2. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Functionally heterogeneous human satellite cells identified by single cell RNA sequencing

   Emilie Barruet et al.
3. 1. Human Biology and Medicine
   2. Stem Cells and Regenerative Medicine

   Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence

   Nicola Alessio et al.
4. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration

   Konstantinos Sousounis et al.

   Experimental manipulation of a core DNA damage response factor and cell-cycle checkpoint regulators reveals a key role for these processes in the progenitor cells that fuel limb regeneration.
5. 1. Stem Cells and Regenerative Medicine

   Long non-coding RNA GRASLND enhances chondrogenesis via suppression of interferon type II signaling pathway

   Nguyen PT Huynh et al.
6. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Coordinated hedgehog signaling induces new hair follicles in adult skin

   Xiaoyan Sun et al.

   Hedgehog-pathway activation in adjacent epithelial and stromal cells, but not in epithelial or stromal cells alone, enables the generation of functional de novo hair follicles in unwounded adult mouse skin.
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts

   Ruihua Ma et al.

   Mouse genetic approaches show that multiple Wnt endothelial sources orchestrate the spatiotemporal distribution of hepatocyte functions during liver maturation and respecify metabolic zonation during liver repair.
8. 1. Stem Cells and Regenerative Medicine

   Multifaceted secretion of htNSC-derived hypothalamic islets induces survival and antidiabetic effect via peripheral implantation in mice

   Yizhe Tang et al.

   A subpopulation of multi-secretory hypothalamic stem cells was developed to form 3D spheres for peripheral application against mortality and symptom of a severe diabetes model.
9. 1. Stem Cells and Regenerative Medicine

   Derivation of trophoblast stem cells from naïve human pluripotent stem cells

   Chen Dong et al.

   Naive hPSCs can readily give rise to human trophoblast stem cells, thus demonstrating their extraembryonic lineage potential and providing a new model system to study human trophectoderm specification.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Tailless/TLX reverts intermediate neural progenitors to stem cells driving tumourigenesis via repression of asense/ASCL1

    Anna E Hakes, Andrea H Brand

    Increased expression of Drosophila Tailless (TLX homologue) reverts intermediate progenitors to neural stem cells, inducing tumourigenesis via Asense repression and reflecting mutually exclusive TLX and ASCL1 expression in human glioblastoma.