Eco-HAB consists of four housing compartments (a), tube-shaped inter-territorial passages (b), radio-frequency identification antennas (c), and impassable, perforated partitions behind which social …
We counted the number of RFID registrations per visually registered crossing under the antenna. The implemented system of coils recognizes subjects at a rate of at least one or more RFID …
For detailed description of behavioral protocols see 'Materials and methods'.
(a) Detailed data regarding quantity of time spent by each mouse with every other animal in the group can be obtained in Eco-HAB. (b) Based on simultaneous territory occupation for each individual, …
Examples show (a) a pair of mice spending most of their time together, regardless of their position within the territory, and (b) a pair of mice spending time mostly in different areas of Eco-HAB. …
Customized software provides easy access to data on the amount of time spent by a mouse in each Eco-HAB compartment. An example here shows mouse activity distribution in 12-hr dark phase during the …
High-stress conditions differ from low-stress conditions in the intensity of light and subjects' and mouse social objects' habituation to the experimenter and the experimental environment (for a …
Figure (a–d) depict tests involving C57BL/6 mice and (e–h) tests involving BALB/c mice. (a) and (e) show social approach in the Eco-HAB system defined as the increase in proportion of time spent in …
Eco-HAB measured social approach and in-cohort sociability of valproate-treated and control C57BL/6 and BALB/c mice.
The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see 'Materials and methods').
Eco-HAB measured social approach and in-cohort sociability of valproate-treated and control C57BL/6 and BALB/c mice.
The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
Eco-HAB measured social approach and in-cohort sociability of valproate-treated and control C57BL/6 and BALB/c mice.
The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
Eco-HAB measured social approach and in-cohort sociability of valproate-treated and control C57BL/6 and BALB/c mice.
The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
Data are represented as mean ± SEM.
We assessed subjects approach to social odor in four different periods, namely 30’, 1 hr, 2 hr, and 4 hr after the presentation of olfactory stimuli, in order to see how their behavior changes with …
Fmr1 knockouts, n = 22. Wild-type controls, n = 10. (a) Odor-based social preference in the Eco-HAB system defined as the increase in proportion of time spent in the compartment with social odor …
Eco-HAB measured social approach and in-cohort sociability of Fmr1 knockouts and wild-type controls.
The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see 'Materials and methods').
Eco-HAB measured social approach and in-cohort sociability of Fmr1 knockouts and wild-type controls.
The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see 'Materials and methods').
Individual results of approach to social odor for all cohorts of (a) valproate-treated (n = 20) and control (n = 18) BALB/c subjects (4 cohorts), (b) valproate-treated (n = 26) and control (n = 35) …
Eco-HAB measured social approach score for valproate-treated and control C57BL/6 and BALB/c mice and Fmr1 knockouts and wild-type controls.
These data are identical to Figure 3A—source data 1, Figure 3E—source data 3, Figure 4A—source data 1 with respect to Figures 3A,E and 4A and are available as a separate file for the readers’ convenience.
Eco-HAB measured social approach score for valproate-treated and control C57BL/6 and BALB/c mice and Fmr1 knockouts and wild-type controls.
These data are identical to Figure 3A—source data 1, Figure 3E—source data 3, Figure 4A—source data 1 with respect to Figures 3A,E and 4A and are available as a separate file for the readers’ convenience.
Eco-HAB measured social approach score for valproate-treated and control C57BL/6 and BALB/c mice and Fmr1 knockouts and wild-type controls.
These data are identical to Figure 3A—source data 1, Figure 3E—source data 3, Figure 4A—source data 1 with respect to Figures 3A,E and 4A and are available as a separate file for the readers’ convenience.
(a, Fmr1 knockout n = 22, wild-type control n = 18) vs. (b, Fmr1 knockout n = 11, wild-type control n = 9). Regardless of experimental environment, evaluation carried out in Eco-HAB revealed …
We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.
The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see 'Materials and methods').
We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.
The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
(a, Fmr1 knockout n = 22, wild-type control n = 18) vs. (b, Fmr1 knockout n = 11, wild-type control n = 9) – gives corresponding results. A histogram illustrating score of Fmr1 knockouts is shifted …
We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.
The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.
The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
Evaluation of social behavior of subjects was repeated twice in identical Eco-HAB experiments, separated by a 10-day period of regular housing. Each aligned dot and square encircled by an oval …
We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.
The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.
The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).
Dominance is expressed as percentage of won encounters ('winning score percent') in the U-tube dominance test (see 'Materials and methods'). Activity in Eco-HAB is defined as the number of visits to …
Raw data from U-tube dominance test and Eco-HAB measured activity (number of visits to all compartments of the apparatus during 1st 12-hr period of adaptation).
Figure 9 depicts correlation between those two variables.
Raw data from U-tube dominance test and Eco-HAB measured activity (number of visits to all compartments of the apparatus during 1st 12 hr period of adaptation).
Figure 9 depicts correlation between those two variables.
Number of episodes and duration of aggressive behaviors in VPA-treated and control BALB/c (a, b), VPA-treated and control C57BL/6 (c, d) and Fmr1 knockout and wild-type mice (e, f) during first 6 hr …
Flashing lights indicate activation of RFID antennas – sensors of the individual recognition system. The clip presents a 30 s period at the beginning of the adaptation phase, when animals are …
Eco-HAB.py scripts with sample data enabling their execution.