Cholesterol activates the G-protein coupled receptor Smoothened to promote morphogenetic signaling

  1. Giovanni Luchetti
  2. Ria Sircar
  3. Jennifer H Kong
  4. Sigrid Nachtergaele
  5. Andreas Sagner
  6. Eamon FX Byrne
  7. Douglas F Covey
  8. Christian Siebold  Is a corresponding author
  9. Rajat Rohatgi  Is a corresponding author
  1. Stanford University School of Medicine, United States
  2. The Francis Crick Institute, United Kingdom
  3. University of Oxford, United Kingdom
  4. Washington University School of Medicine, United States
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  1. Giovanni Luchetti
  2. Ria Sircar
  3. Jennifer H Kong
  4. Sigrid Nachtergaele
  5. Andreas Sagner
  6. Eamon FX Byrne
  7. Douglas F Covey
  8. Christian Siebold
  9. Rajat Rohatgi
(2016)
Cholesterol activates the G-protein coupled receptor Smoothened to promote morphogenetic signaling
eLife 5:e20304.
https://doi.org/10.7554/eLife.20304