Freezing suppression by oxytocin in central amygdala allows alternate defensive behaviours and mother-pup interactions
- Champalimaud Neuroscience Programme, Portugal
- New York University School of Medicine, United States
- Nathan Kline Institute for Psychiatric Research, United States
Figures
Figure 1
Rat dams suppress freezing when in the presence of their pups.
(A) Schematic of the experimental design. (B) Raster plot showing behaviors of dams during test to the conditioned odor. Each row corresponds to one dam. Dams are sorted by treatment, PP19-21 dams …
Figure 2
Maternal response is dependent on stage.
(A) Schematic of experimental design. Rat dams (PP4-6, n=10, PP19-21, n=12) were first exposed with their own pups (ex. PP4-6 pups), reconditioned, and then re-exposed to the threat in the presence …
Figure 3
Freezing suppression by oxytocin in central amygdala in PP4-6 dams allows alternate maternal defensive behaviors and mother-pup interactions during threat.
(A) Schematic of experimental design. (B) Schematic of coronal sections (adapted from Paxino and Watson’s atlas) with empty black and red circles corresponding to CONT and OTA cannula placements, …
Figure 4
Freezing suppression by oxytocin in central amygdala in PP19-21 dams allows alternate maternal defensive behaviors and mother-pup interactions during threat.
(A) Schematic of experimental design. (B) Schematic of coronal sections (adapted from Paxino and Watson’s atlas) with empty black and red circles corresponding to PBS and OTA cannula placements, …
Figure 5
Transmission of fear from mother to pup.
(A) Schematic of the experimental design. PP19-21 pups were re-exposed to the odor alone 2–3 days after exposure with rat dam. (B) Line graph shows timecourse of immobility (average ± SEM) displayed …
Videos
Video 1
Video clip taken during the test session, when conditioned dams were re-exposed to conditioned odor with and without pups (PP4-6 and PP19-21).
Video clip starts at the time of first odor delivery.
