(A) The mutant exhibited white coat color, diluted iris pigmentation and hearing loss. Histologic sections were examined from the cochleas of mutant pigs, and the striae vascularis exhibited enlarged marginal cell nuclei and tectorial membrane, indicating an abnormal organ of Corti. (B) The mutant exhibited white coat color and hearing loss. Histologic analyses of the cochleas from mutant pigs showed an extensive collapse of Reissner’s membrane onto the stria vascularis and the organ of Corti. In addition, the auditory hair cells were absent or severely diminished, and the supporting cells displayed severe abnormalities. (C) The mutant was characterized by shaking and trembling, and progressive muscle weakness was also observed. (D) The mutant presented elevated blood glucose levels (hyperglycemia). Thesemutants exhibited 212.8% higher blood glucose concentrations (mutants: 8.3 mg/dL, WT: 3.9 mg/dL). (E) The mutant was identified by its black coat color. (F) the mutant showed short limbs and small body size, and this phenotype was inherited with a dominant model. (G) Line TBB007T095. The mutant was characterized by hearing loss, white coat color and diluted iris pigmentation. SOX10 was identified as the causative gene, and this mutant may represent the first inherited animal model of human Mondini dysplasia. The mutant phenotypes shown in (A–G) exhibit dominant inheritance. (H) The mutants from three mutant lines (Z0017, Z0022 and Z0040) presented ‘single-end black’ coat color phenotype. Linkage analysis of line Z0040 revealed a significant signal at chr13: 49–76 Mb region. The G1 boars of lines Z0017, Z0022 and Z0040 were derived from different G0 boars, and further analysis might identify additional linkage regions in lines Z0017 and Z0022. (I) The mutant displayed diluted brown coat color (line Z0015). (J) The mutant showed ectropion, flattening of the ears and large, thick, plate-like scales over the entire body (line Z0009). (K) The mutant showed neonatal death, congenital malformations of the limbs, and a shortened lower jaw (line Z0037). (L) The mutant, presenting an autosomal recessive pattern of inheritance, displayed weak in vitality and nude skin (line Z0013). (M) The mutants from lines Z0078 and Z0079 presented abnormal facial and limb development. The G1 boars of lines Z0078 and Z0079 were derived from the same G0 boar, suggesting the same causative genes for these two mutant lines. (N) The mutant line had increased body weight and high daily weight gain that was inherited in a recessive manner (line Z0006). (O) The mutant, which is inherited with a recessive model, is associated with short limbs, small body size, and low body weight (line Z0071). The mutant phenotypes (H–O) exhibit recessive inheritance.