Perceptual processing in the ventral visual stream requires area TE but not rhinal cortex
- National Institute of Mental Health, National Institutes of Health, United States
- National Institute of Advanced Industrial Science and Technology, Japan
- National Institute of Neurological Disorders and Stroke, National Institutes of Health, United States
Figures
Figure 1 with 1 supplement
Background and task.
(A) Ventral visual stream - simple features represented in primary visual cortex (green). Increasing complexity of representations in intermediate areas, culminating in the representation of whole …
Figure 1—figure supplement 1
Estimates of the extent of the aspiration lesions of the three monkeys in the TE-lesioned group (top), and rhinal-lesioned group (bottom) are plotted on coronal sections at the indicated levels, and reconstructed onto lateral/ventral views of the macaque brain, respectively; reconstructions for each case are shown at the bottom of each column.
Lesions were reconstructed using MR images (see Matsumoto et al., 2016) for details). Across the groups, lesions largely covered the areas of interest, and damage to adjacent structures was minimal …
Figure 2
Experiment 1.
(A, B, C) Categorization performance of control (n = 3), TE-lesioned (n = 3), and rhinal-lesioned (n = 3) groups, respectively, during the first 10 presentations of this stimulus set (10 of 16 total …
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Figure 2—source data 1
Experiment 1 - learning to categorize morphed images.
- https://doi.org/10.7554/eLife.36310.005
Figure 3 with 2 supplements
Experiment 2.
(A) Categorization performance of three groups of monkeys: controls (n = 3), TE-lesioned group (n = 3), and Rh-lesioned group (n = 3), mean (±s.e.m.) of presentations 10 to 20. Data fit with the …
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Figure 3—source data 1
Experiment 2 - asymptotic categorization performance.
- https://doi.org/10.7554/eLife.36310.009
Figure 3—figure supplement 1
The cat-dog morphed images presented as visual stimuli in Experiment 2.
A total of 20 morph series (one per row) were used for this experiment. Each stimulus was presented once per set, in pseudo-random order; the monkeys completed two sets each day.
Figure 3—figure supplement 2
(A) Categorization performance of individual monkeys performing Experiment 2.
Data fit with the function: a + b/(1 + exp(c * x + d)), where a, b, c, and d are free parameters. (C, D, E) Reaction times (±s.e.m.) of individual monkeys for trials ending with a correct response. …
Figure 4
Visual acuity testing.
Contrast sensitivity is plotted on a logarithmic scale against spatial frequency. Mean sensitivity (±s.e.m.) for each of the three groups of monkeys - controls (n = 3), TE-lesioned group (n = 3), …
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Figure 4—source data 1
Visual acuity testing.
- https://doi.org/10.7554/eLife.36310.011
Figure 5 with 1 supplement
Experiment 3.
(A) Examples of the visual stimuli presented. Four checker-board masks were placed over each of the stimuli used in Experiment 1, and presented inter-leaved with an unmasked version of each …
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Figure 5—source data 1
Experiment 3 - categorization of visually degraded stimuli.
- https://doi.org/10.7554/eLife.36310.014
Figure 5—figure supplement 1
(A, C, E) Categorization performance on unmasked stimuli presented in Experiment 3, for individual control (A), TE-lesioned (C), and rhinal-lesioned (E) monkeys.
(B, D, F) Performance on masked (mean of all masks) stimuli (first presentation) for each group: (B) control, (D) TE-lesioned, (F) rhinal-lesioned.
Figure 6 with 2 supplements
Experiment 4.
(A) Examples of the visual stimuli presented; each cat was morphed with two dogs, and vice versa, for example Cat A was morphed with Dog A (top row), and with Dog B (bottom row). Examples at the 0%, …
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Figure 6—source data 1
Experiment 4 - categorization of novel stimuli.
- https://doi.org/10.7554/eLife.36310.018
Figure 6—figure supplement 1
Examples of the cat-dog morphed images presented as visual stimuli in Experiment 4.
Twelve morph series – one on each row – are shown. A total of 40 morph series were used for this experiment. Each stimulus was presented once, in pseudo-random order; the monkeys completed a single …
Figure 6—figure supplement 2
Categorization performance of individual monkeys in Experiment 4, in which each stimulus was novel, and presented only once.
https://doi.org/10.7554/eLife.36310.017Additional files
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Transparent reporting form
- https://doi.org/10.7554/eLife.36310.019
