(A) The stimulus consisted of a checkerboard presented for 200 ms accompanied for the duration by auditory white noise. Subjects were asked to respond with a button press following the stimulus. Stimuli were presented with fixed or randomized inter-stimulus intervals in 20 s blocks. Stimulus blocks alternated with 20 s of fixation. (B) Reaction times were shorter for ASD compared to NT participants from the second trial and on. (*)=p < 0.05. (C) ROIs in left and right visual and left and right auditory areas were selected based on activation to stimulus versus fixation blocks over the three experimental runs. Probability maps/heat maps showing auditory and visual ROI locations for NT (top) and ASD (bottom) participants. Percent overlap across subjects calculated in Talairach space and displayed on an individual subject’s anatomical image.