(A) Relevant parameters and their relation for modeling and estimation of rates, where is the concentration of the donor, acceptor or junction bond. (B) Comparison of estimated donor synthesis rates (left), acceptor synthesis rates (middle) and junction half-life (right) of 1st against 2nd, 2nd against 3rd, 3rd against 4th and 4th against 5th introns in major isoforms, with the corresponding Spearman correlation. (C) Number of antisense RNAs (asRNA, n=162), lincRNAs (n=204), mRNAs (n=8,770) and other ncRNAs (n=290) with respect to the GENCODE annotation for which kinetic rates were estimated. (D) Major-isoform aggregated synthesis, splicing and degradation rates estimated by Mukherjee et al. (2017) against this study, with corresponding Spearman correlation and P-value. (E) Number of junctions belonging to antisense RNAs (asRNA, n= 462), lincRNAs (n=644), mRNAs (n=84,749) and other ncRNAs (n= 1,196) with respect to the GENCODE annotation for which kinetic rates were estimated. (F-J) Distribution of site-specific rates of donor synthesis rate (F), acceptor synthesis rate (G), donor bond half-life (H), acceptor bond half-life (I) and junction bond half-life (J) for junctions in mRNAs (n=84,749), lincRNAs (n=644) antisense RNAs (auRNA, n=462), and other ncRNAs (n=1,196). Black bars represent the median values for each group. Lower and upper boxes are the first and third quartile, respectively. Mirrored curves show density estimates (B,C, E-J based on Supplementary file 2).