1. Neuroscience
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One-shot learning and behavioral eligibility traces in sequential decision making

  1. Marco P Lehmann  Is a corresponding author
  2. He A Xu
  3. Vasiliki Liakoni
  4. Michael H Herzog
  5. Wulfram Gerstner
  6. Kerstin Preuschoff
  1. École Polytechnique Fédérale de Lausanne, Switzerland
  2. University of Geneva, Switzerland
Research Article
  • Cited 3
  • Views 2,072
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Cite this article as: eLife 2019;8:e47463 doi: 10.7554/eLife.47463

Abstract

In many daily tasks we make multiple decisions before reaching a goal. In order to learn such sequences of decisions, a mechanism to link earlier actions to later reward is necessary. Reinforcement learning theory suggests two classes of algorithms solving this credit assignment problem: In classic temporal-difference learning, earlier actions receive reward information only after multiple repetitions of the task, whereas models with eligibility traces reinforce entire sequences of actions from a single experience (one-shot). Here we show one-shot learning of sequences. We developed a novel paradigm to directly observe which actions and states along a multi-step sequence are reinforced after a single reward. By focusing our analysis on those states for which RL with and without eligibility trace make qualitatively distinct predictions, we find direct behavioral (choice probability) and physiological (pupil dilation) signatures of reinforcement learning with eligibility trace across multiple sensory modalities.

Data availability

The datasets generated during the current study are available on Dryad, at the following address https://dx.doi.org/10.5061/dryad.j7h6f69

The following data sets were generated

Article and author information

Author details

  1. Marco P Lehmann

    School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
    For correspondence
    marco.lehmann@alumni.epfl.ch
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-5274-144X
  2. He A Xu

    School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
    Competing interests
    The authors declare that no competing interests exist.
  3. Vasiliki Liakoni

    School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
    Competing interests
    The authors declare that no competing interests exist.
  4. Michael H Herzog

    School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
    Competing interests
    The authors declare that no competing interests exist.
  5. Wulfram Gerstner

    School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
    Competing interests
    The authors declare that no competing interests exist.
  6. Kerstin Preuschoff

    Swiss Center for Affective Sciences, University of Geneva, Genève, Switzerland
    Competing interests
    The authors declare that no competing interests exist.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (CRSII2 147636 (Sinergia))

  • Marco P Lehmann
  • He A Xu
  • Vasiliki Liakoni
  • Michael H Herzog
  • Wulfram Gerstner
  • Kerstin Preuschoff

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (CRSII2 200020 165538)

  • Marco P Lehmann
  • Vasiliki Liakoni
  • Wulfram Gerstner

Horizon 2020 Framework Programme (Human Brain Project (SGA2) 785907)

  • Michael H Herzog
  • Wulfram Gerstner

H2020 European Research Council (268 689 MultiRules)

  • Wulfram Gerstner

Horizon 2020 Framework Programme (Human Brain Project (SGA1) 720270)

  • Michael H Herzog
  • Wulfram Gerstner

The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.

Ethics

Human subjects: Experiments were conducted in accordance with the Helsinki declaration and approved by the ethics commission of the Canton de Vaud (164/14 Titre: Aspects fondamentaux de la reconnaissance des objets : protocole général). All participants were informed about the general purpose of the experiment and provided written, informed consent. They were told that they could quit the experiment at any time they wish.

Reviewing Editor

  1. Thorsten Kahnt, Northwestern University, United States

Publication history

  1. Received: April 5, 2019
  2. Accepted: November 1, 2019
  3. Accepted Manuscript published: November 11, 2019 (version 1)
  4. Version of Record published: December 6, 2019 (version 2)

Copyright

© 2019, Lehmann et al.

This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

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