1. Ecology
  2. Evolutionary Biology
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Eco-evolutionary dynamics of nested Darwinian populations and the emergence of community-level heredity

  1. Guilhem Doulcier  Is a corresponding author
  2. Amaury Lambert
  3. Silvia De Monte
  4. Paul B Rainey
  1. École supérieure de physique et de chimie industrielle de la ville de Paris, PSL University, France
  2. Collège de France, France
  3. École Normale Supérieure, France
  4. Max Planck Institute for Evolutionary Biology, Germany
Research Article
  • Cited 10
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Cite this article as: eLife 2020;9:e53433 doi: 10.7554/eLife.53433

Abstract

Interactions among microbial cells can generate new chemistries and functions, but exploitation requires establishment of communities that reliably recapitulate community-level phenotypes. Using mechanistic mathematical models, we show how simple manipulations to population structure can exogenously impose Darwinian-like properties on communities. Such scaffolding causes communities to participate directly in the process of evolution by natural selection and drives the evolution of cell-level interactions to the point where, despite underlying stochasticity, derived communities give rise to offspring communities that faithfully re-establish parental phenotype. The mechanism is akin to a developmental process (developmental correction) that arises from density dependent interactions among cells. Knowledge of ecological factors affecting evolution of developmental correction has implications for understanding the evolutionary origin of major egalitarian transitions, symbioses, and for top-down engineering of microbial communities.

Data availability

The source code for all simulations and figures in the manuscript isavailable as a zip file uploaded with the manuscript and in a public gitrepository (https://gitlab.com/ecoevomath/estaudel).

Article and author information

Author details

  1. Guilhem Doulcier

    Laboratoire de Génétique de l'Evolution, CNRS UMR 8231, École supérieure de physique et de chimie industrielle de la ville de Paris, PSL University, Paris, France
    For correspondence
    guilhem.doulcier@ens.fr
    Competing interests
    No competing interests declared.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0003-3720-9089
  2. Amaury Lambert

    Center for Interdisciplinary Research in Biology(CIRB), Collège de France, Paris, France
    Competing interests
    No competing interests declared.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0002-7248-9955
  3. Silvia De Monte

    Institut de Biologie de l'´Ecole Normale Sup´erieure, École Normale Supérieure, Paris, France
    Competing interests
    No competing interests declared.
  4. Paul B Rainey

    Department of Microbial Population Biology, Max Planck Institute for Evolutionary Biology, Plön, Germany
    Competing interests
    Paul B Rainey, PBR is a founder of MilliDrop InstrumentsReviewing editor, eLife.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0003-0879-5795

Funding

Agence Nationale de la Recherche (ANR-10-IDEX-001-02)

  • Guilhem Doulcier
  • Paul B Rainey

Agence Nationale de la Recherche (ANR-10-LABX-54)

  • Silvia De Monte

Agence Nationale de la Recherche (ANR-11-IDEX-0001-02)

  • Silvia De Monte

Max-Planck-Gesellschaft

  • Paul B Rainey

The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.

Reviewing Editor

  1. Wenying Shou, Fred Hutchinson Cancer Research Center, United States

Publication history

  1. Received: November 7, 2019
  2. Accepted: June 12, 2020
  3. Accepted Manuscript published: July 7, 2020 (version 1)
  4. Version of Record published: August 20, 2020 (version 2)

Copyright

© 2020, Doulcier et al.

This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

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