Enhancer architecture sensitizes cell-specific responses to Notch gene dose via a bind and discard mechanism

  1. Yi Kuang
  2. Ohad Golan
  3. Kristina Preusse
  4. Brittany Cain
  5. Collin J Christensen
  6. Joseph Salomone
  7. Ian Campbell
  8. FearGod V Okwubido-Williams
  9. Matthew R Hass
  10. Zhenyu Yuan
  11. Nathanel Eafergan
  12. Kenneth H Moberg
  13. Rhett A Kovall
  14. Raphael Kopan  Is a corresponding author
  15. David Sprinzak  Is a corresponding author
  16. Brian Gebelein  Is a corresponding author
  1. Cincinnati Children's Hospital Research Foundation, United States
  2. Tel Aviv University, Israel
  3. Cincinnati Children's Hospital Medical Center, United States
  4. University of Cincinnati, United States
  5. Emory University, United States
  6. Cincinnati Children's hospital, United States
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  1. Yi Kuang
  2. Ohad Golan
  3. Kristina Preusse
  4. Brittany Cain
  5. Collin J Christensen
  6. Joseph Salomone
  7. Ian Campbell
  8. FearGod V Okwubido-Williams
  9. Matthew R Hass
  10. Zhenyu Yuan
  11. Nathanel Eafergan
  12. Kenneth H Moberg
  13. Rhett A Kovall
  14. Raphael Kopan
  15. David Sprinzak
  16. Brian Gebelein
(2020)
Enhancer architecture sensitizes cell-specific responses to Notch gene dose via a bind and discard mechanism
eLife 9:e53659.
https://doi.org/10.7554/eLife.53659