The human cortex is characterized by local morphological features such as cortical thickness, myelin content, and gene expression that change along the posterior-anterior axis. We investigated if some of these structural gradients are associated with a similar gradient in a prominent feature of brain activity - namely the frequency of oscillations. In resting-state MEG recordings from healthy participants (N=187) using mixed effect models, we found that the dominant peak frequency in a brain area decreases significantly along the posterior-anterior axis following the global hierarchy from early sensory to higher-order areas. This spatial gradient of peak frequency was significantly anticorrelated with that of cortical thickness, representing a proxy of the cortical hierarchical level. This result indicates that the dominant frequency changes systematically and globally along the spatial and hierarchical gradients and establishes a new structure-function relationship pertaining to brain oscillations as a core organization that may underlie hierarchical specialization in the brain
We have used online dataset for this study.
A 204-subject multimodal neuroimaging dataset to study language processing10.1038/s41597-019-0020-y.
- Keyvan Mahjoory
- Jan-Mathijs Schoffelen
- Joachim Gross
- Joachim Gross
The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.
- Laura Dugué, Université de Paris, France
© 2020, Mahjoory et al.
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