(A,B) Example images, responses, and reconstructions from ON and OFF parasol cells. Top left: original image. Top right: Parasol cell mosaics shaded by their response value (ON - blue, middle, OFF - orange, right). Bottom left: reconstruction from both cell types. Bottom right: reconstruction from just ON (blue, middle) or just OFF (orange, right) parasol cells. (C) Reconstruction performance for ON vs. OFF (top), both vs. ON (middle), and both vs. OFF (bottom), with n = 2250 images from 15 recordings. (D) Average estimated pixel intensity (top) and sensitivity (bottom, defined as Δaverage estimated pixel intensity/Δtrue pixel intensity) vs. true pixel intensity for ON (blue), OFF (orange), and both (black). Individual recordings are shown in the top plot, with the average in bold. Source files for C and D are available in Figure 6—source data 1.