Long non-coding RNAs in regulation of adipogenesis and adipose tissue function
- Department of Experimental Medicine, Biotechnology, and Molecular Biology Section, University of Campania Luigi Vanvitelli, Italy
- Institute Bioscience and BioResources, CNR, Italy
Figures
Figure 1
Types of RNAs present in eukaryotic cells.
RNAs are primarily divided between coding RNAs and noncoding RNAs. Coding RNAs contain one class of molecules: the messenger RNAs (mRNAs) that undergo the translation process. The other category …
Figure 2
Some examples of lncRNA activity as a regulator of gene expression.
LncRNAs, working on proximal loci or at a great distance, can inhibit or activate the expression gene at various levels: i) chromatin modification and remodeling; ii) transcriptional control, and …
Figure 3
Summary of lncRNAs activity during adipogenesis.
Mesenchymal stromal cells contain stem cells that can be committed to white or brown precursor cells able to differentiate in white or brown adipocytes, respectively. A specific subpopulation of …
Tables
Table 1
Size and accession number of cited lncRNAs involved in adipogenesis.
| Homo sapiens | Mus musculus | |
|---|---|---|
| Blnc1 | 759 nt URS0000DBDC4C_9606 | 965 nt URS0000D77FA2_10090 |
| Lnc-BATE1 | 894 nt URS000075C5E3_10090 | |
| AK079912 | N.D. | N.D. |
| LncBATE10 | 1808 nt URS000075F077_10090 | |
| MIAT | 10,194 nt URS00007E4AF8_9606 | 9163 nt URS0000760956_10090 |
| LINC01119* | 1210 nt URS000075CEA4_9606 | |
| LINC02202 * | 2863 nt URS000075A437_9606 | |
| NONMMUG024827 | N.D | N.D. |
| H19* | 2.362 nt URS0000812128_960 | 2286 nt URS0000767B73_10090 |
| ASMER-1 | N.D. | N.D. |
| ASMER-2 | N.D. | N.D. |
| Plnc1 | N.D. | N.D. |
| SRA | 875 nt URS00001A8152_9606 | 829 nt URS00003EA2D2_10090 |
| ADINR | 2252 nt URS0000CCE086_9606 | |
| HOTAIR* | 2364 nt URS000075C808_9606 | 2222 nt URS000075BAE8_10090 |
| PVT1* | 1957 nt URS00008E3A67_9606 | 3319 nt URS000077AEFF_10090 |
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*These lncRNAs have alternative transcripts.
N.D. Not Detected in RNA database (https://rnacentral.org).
