(a-b) Bifactor analysis of item-level scores from the STAI, BDI, MASQ, PSWQ, CESD, and EPQ-N (128 items in total) revealed a general ‘negative affect’ factor (xaxis) and two specific factors: one …
Bifactor analysis was applied to the item-level scores from the STAI, BDI, MASQ, PSWQ, CESD, and EPQ-N (128 items in total) for participants in experiment 1. Prior to the estimation of the bifactor …
(a) We calculated summary scores for each participant for each of the standardized questionnaires we administered. All participants who completed the full set of questionnaires were included: this …
(a) On each trial, participants chose between two shapes. One of the two shapes led to receipt of shock or reward on each trial, the nature of the outcome depending on the version of the task. The …
(a) This panel shows the posterior means along with the 95% highest posterior density intervals (HDI) for the group means () for each learning rate component (i.e. for baseline learning rate and …
Panel (a) shows posterior means and 95% highest posterior density intervals (HDI) for the effect of general factor scores () on each of the learning rate components. General factor scores credibly …
Panel (a) and panel (b) show the effects of depression-specific factor scores and anxiety-specific factor scores, respectively, on each of the learning rate components (e.g. ). The 95%-HDI’s for …
Panel (a) shows posterior means and 95% highest posterior density intervals (HDI) for the effect of general factor scores () on each of the learning rate components. Replicating findings from …
(a) This panel shows the posterior means along with the 95% highest posterior density intervals (HDI) for the group means () for each learning rate component (i.e. for baseline learning rate and …
Panel (a) and panel (b) show the effects of depression-specific factor scores and anxiety-specific factor scores, respectively, on each of the learning rate components (e.g. ). The 95%-HDI’s for …
Posterior mean parameter estimates for participants from experiment 1 were used to simulate new choice data from the winning model (#11). The model was then re-fit to each of these simulated …
Posterior mean parameter estimates for participants from experiment 1 were used to simulate new choice data from the winning model (#11). As in Appendix 4—figure 1, we show the results of parameter …
The robustness of the estimates for the population-level parameters () was explored by examining the variability in parameter values across the 10 simulated datasets (blue data points). …
The robustness of the estimates for the population-level parameters () was explored by examining the variability in parameter values across the 10 simulated datasets (blue data points). …
In experiment 1, we additionally fit a model that included the three-way interaction of block type (volatile, stable), relative outcome value (good, bad), and task version (reward, aversive) for …
The four panels depict the performance of participants in each block (stable left column; volatile right column) and in each task (reward top row; punishment bottom row). Data from experiment 1 is …
Two alternative models were fit to the behavioral data from experiment 1, in addition to the main bifactor model. For the first alternative model, population-level parameters entered comprised …
In addition to the main bifactor model, an additional alternative model was also fit to the behavioral data from experiment 2. In this model (the second alternate model described in Appendix …
For each participant, we calculated the number of trials on which they switched choice of shape. As described under parameter recovery, each participant’s posterior means for each of model #11 …
For each participant, we calculated the number of trials on which they switched choice of shape. As described under parameter recovery, each participant’s posterior means for each of model #11 …
Scores on the first PC correlated highly with general factor scores (r=0.9). Scores on the second PC correlated strongly positively with PSWQ (r=0.59), and moderately negatively with MASQAD …
Participant recruitment group | Major Depressive Disorder (MDD) | Generalized Anxiety Disorder (GAD) | Healthy Controls | Unselected Community Sample |
---|---|---|---|---|
Participants Total N (N for reward task, N for aversive task) | 20 (19, 17) | 12 (10, 11) | 24 (22, 19) | 30 (29, 30) |
Female | 10 (10, 8) | 11 (9, 10) | 16 (14, 13) | 13 (12, 13) |
Age mean ± sd (for reward task, for aversive task) | 31 ± 10 (31 ± 10, 28 ± 10) | 32 ± 9 (31 ± 9, 32 ± 9) | 27 ± 6 (27 ± 6, 28 ± 6) | 27 ± 5 (27 ± 5, 27 ± 5) |
STAI mean ± sd (for reward task, for aversive task) | 59 ± 6 (59 ± 7, 58 ± 6) | 58 ± 9 (60 ± 9, 57 ± 9) | 40 ± 12 (41 ± 12, 41 ± 12) | 36 ± 12 (36 ± 11, 36 ± 12) |
BDI mean ± sd (for reward task, for aversive task) | 24 ± 9 (25 ± 9, 23 ± 9) | 20 ± 11 (22 ± 10, 20 ± 11) | 7 ± 7 (7 ± 7, 7 ± 8) | 6 ± 8 (5 ± 7, 6 ± 8) |
MASQ-AD mean ± sd (for reward task, for aversive task) | 80 ± 10 (81 ± 10, 79 ± 10) | 74 ± 16 (75 ± 17, 73 ± 16) | 55 ± 18 (56 ± 18, 56 ± 19) | 50 ± 20 (48 ± 18, 50 ± 20) |
MASQ-AA mean ± sd (for reward task, for aversive task) | 28 ± 7 (28 ± 7, 28 ± 7) | 33 ± 10 (34 ± 11, 34 ± 10) | 21 ± 4 (21 ± 4, 20 ± 2) | 22 ± 6 (22 ± 6, 22 ± 6) |
PSWQ mean ± sd (for reward task, for aversive task) | 62 ± 14 (61 ± 14, 60 ± 14) | 76 ± 9 (75 ± 9, 75 ± 9) | 52 ± 13 (54 ± 12, 51 ± 14) | 42 ± 15 (42 ± 15, 42 ± 15) |
CESD mean ± sd (for reward task, for aversive task) | 30 ± 9 (30 ± 9, 28 ± 8) | 30 ± 14 (32 ± 14, 30 ± 14) | 12 ± 8 (12 ± 8, 11 ± 8) | 10 ± 11 (9 ± 10, 10 ± 11) |
EPQ-N mean ± sd (for reward task, for aversive task) | 18 ± 3 (18 ± 3, 17 ± 3) | 19 ± 4 (19 ± 3, 18 ± 4) | 10 ± 6 (11 ± 6, 10 ± 6) | 10 ± 6 (10 ± 6, 10 ± 6) |
General Factor mean ± sd (for reward task, for aversive task) | 1.1 ± 0.8 (1.1 ± 0.9, 1.0 ± 0.8) | 1.3 ± 1.0 (1.5 ± 1.0, 1.4 ± 1.0) | −0.3 ± 0.8 (−0.2 ± 0.8,–0.4 ± 0.7) | −0.2 ± 0.8 (−0.3 ± 0.7,–0.2 ± 0.8) |
Depression-Specific Factor mean ± sd (for reward task, for aversive task) | 0.8 ± 1.0 (0.9 ± 1.0, 0.8 ± 1.1) | −0.0 ± 0.8 (−0.1 ± 0.8,–0.1 ± 0.7) | 0.1 ± 1.2 (0.1 ± 1.2, 0.3 ± 1.2) | −0.2 ± 0.9 (−0.2 ± 0.9,–0.2 ± 0.9) |
Anxiety-Specific Factor mean ± sd (for reward task, for aversive task) | −0.5 ± 1.1 (−0.5 ± 1.1,–0.6 ± 1.2) | 0.8 ± 0.9 (0.5 ± 0.8, 0.7 ± 0.9) | −0.2 ± 0.9 (−0.1 ± 0.8,–0.1 ± 0.9) | −0.3 ± 1.1 (−0.3 ± 1.1,–0.3 ± 1.1) |
STAI = Spielberger State-Trait Anxiety Inventory (form Y; Spielberger et al., 1983) BDI = Beck Depression Inventory (Beck et al., 1961) MASQ-AD/MASQ AA=anhedonic depression and anxious arousal subscales for the Mood and Anxiety Symptoms Questionnaire (Clark and Watson, 1995; Watson and Clark, 1991) PSWQ = Penn State Worry Questionnaire (Meyer et al., 1990) CESD = Center for Epidemiologic Studies Depression Scale (Radloff, 1977) EPQ-N = the Neuroticism subscale for the 80-item Eysenck Personality Questionnaire (Eysenck and Eysenck, 1975). The two healthy control participants whose data were excluded from both tasks are omitted from this table.
Number of participants (Total N) | 199 |
---|---|
Female (N) | 120 |
Age (mean ± sd) | 21 ± 4 |
STAI (mean ± sd) | 44 ± 9 |
BDI (mean ± sd) | 7 ± 6 |
MASQ-AD (mean ± sd) | 54 ± 15 |
MASQ-AA (mean ± sd) | 24 ± 8 |
PSWQ (mean ± sd) | 57 ± 13 |
CESD (mean ± sd) | 24 ± 8 |
EPQ-N (mean ± sd) | 6 ± 4 |
General Factor (mean ± sd) | −0.1 ± 1.0 |
Depression-Specific Factor (mean ± sd) | 0.4 ± 1.0 |
Anxiety-Specific Factor (mean ± sd) | −0.1 ± 1.0 |
STAI = Spielberger State-Trait Anxiety Inventory (form Y; Spielberger et al., 1983) BDI = Beck Depression Inventory (Beck et al., 1961) MASQ-AD/MASQ AA=anhedonic depression and anxious arousal subscales for the Mood and Anxiety Symptoms Questionnaire (Clark and Watson, 1995; Watson and Clark, 1991) PSWQ = Penn State Worry Questionnaire (Meyer et al., 1990) CESD = Center for Epidemiologic Studies Depression Scale (Radloff, 1977) EPQ-N = the Neuroticism subscale for the 80-item Eysenck Personality Questionnaire (Eysenck and Eysenck, 1975).
Participants (Total N) | 147 |
---|---|
Female (N) | 64 |
Age | Not recorded; required to be 18 years or older. |
STAI (mean ± sd) | 43 ± 13 |
BDI (mean ± sd) | 11 ± 12 |
MASQ-AD (mean ± sd) | 63 ± 18 |
MASQ-AA (mean ± sd) | 23 ± 8 |
General Factor (mean ± sd) | −0.1 ± 0.9 |
Depression-Specific Factor (mean ± sd) | −0.2 ± 0.9 |
Anxiety-Specific Factor (mean ± sd) | 0.1 ± 1.0 |
STAI = Spielberger State-Trait Anxiety Inventory (form Y; Spielberger et al., 1983); BDI = Beck Depression Inventory (Beck et al., 1961) MASQ-AD/MASQ AA=anhedonic depression and anxious arousal subscales for the Mood and Anxiety Symptoms Questionnaire (Clark and Watson, 1995; Watson and Clark, 1991).
Thirteen models were fit to participants’ choice data from experiment 1. Models were fit hierarchically and compared using leave-one-out cross validation error approximated by Pareto smoothed …
Model Number | Parameters | # of Parameter Components | PSIS-LOO |
---|---|---|---|
Model #1 | 12 | 27,801 | |
Model #2 | 12 | 26,164 | |
Model #3 | 15 | 25,550 | |
Model #4 | 18 | 26,042 | |
Model #5 | 21 | 25,462 | |
Model #6 | 24 | 25,486 | |
Model #7 | 23 | 25,154 | |
Model #8 | 25 | 25,185 | |
Model #9 | 27 | 25,377 | |
Model #10 | 27 | 25,325 | |
Model #11 ** | 26 | 25,037 | |
Model #12 | 32 | 25,216 | |
Model #13 | 32 | 25,181 |
1:Unless otherwise stated, each parameter is divided into four parameter components: a shared baseline parameter across blocks and tasks, and differences in the parameter between stable and volatile blocks (volatile-stable), between different task versions (reward-aversive) and an interaction of those differences (reward-aversive)x(volatile-stable).
gb: For each parameter with this superscript, three additional parameter components were added for the relative value of previous outcome (good-bad) and the interactions of relative outcome value with block type (volatile-stable)x(good-bad) and task version (reward-aversive)x(good-bad).
ra only: For each parameter with this superscript, only differences in the parameters between the reward and aversive task versions (reward-aversive) were included.
baseline: For each parameter with this superscript, only one single baseline parameter was used, across both task versions and volatile and stable blocks.
**Indicates best fitting model.
The same 13 models fit to participants’ choice data from experiment 1 were also fit to participants’ choice data from experiment 2. Models were fit hierarchically and compared using leave-one-out …
Model Number | Parameters | # of Parameter Components | PSIS-LOO |
---|---|---|---|
Model #1 | 1 | 12 | 57,520 |
Model #2 | 12 | 54,002 | |
Model #3 | 15 | 52,918 | |
Model #4 | 18 | 53,755 | |
Model #5 | 21 | 52,758 | |
Model #6 | 24 | 52,769 | |
Model #7 | 23 | 52,139 | |
Model #8 | 25 | 52,136 | |
Model #9 | 27 | 52,083 | |
Model #10 | 27 | 52,169 | |
Model #11 | 26 | 52,048 | |
Model #12 | 32 | 52,005 | |
Model #13 | 32 | 52,084 |
1:Unless otherwise stated, each parameter is divided into four parameter components: a shared baseline parameter across blocks and tasks, and differences in the parameter between stable and volatile blocks (volatile-stable), between different task versions (gain-loss) and an interaction of those differences (gain-loss)x(volatile-stable).
gb: For each parameter with this superscript, three additional parameter components were added for the relative value of previous outcome (good-bad) and the interactions of this difference with block type (volatile-stable)x(good-bad), and task version (gain-loss)x(good-bad). gl only: For each parameter with this superscript, only differences in the parameters between the reward gain and reward loss task versions (gain-loss) were included.
baseline: For each parameter with this superscript, only one single baseline parameter was used, across both task versions and volatile and stable blocks.