Connectional asymmetry of the inferior parietal lobule shapes hemispheric specialization in humans, chimpanzees, and rhesus macaques
- Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, China
- Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, China
- National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, China
- University of Chinese Academy of Sciences, China
- Center for Language and Brain, Shenzhen Institute of Neuroscience, China
- Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, United States
- State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, China
- Beijing Key Laboratory of Brain Imaging and Connectomics, Beijing Normal University, China
- CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Automation, Chinese Academy of Sciences, China
Figures
Figure 1 with 2 supplements
Framework of the connectivity-based brain parcellation for macaques, chimpanzees, and humans.
(A) Defining the seed masks of the inferior parietal lobule (IPL) in surface space according to the gyri and sulci. (B) Connectivity-based parcellation using anatomical connectivity. Probabilistic …
Figure 1—figure supplement 1
Two- to five-cluster parcellation of the IPL.
The two- to four-cluster solutions showed a consistent rostral–caudal pattern. In the five-cluster solution, a ventral cluster emerged in chimpanzees and a dorsal cluster emerged in humans.
Figure 1—figure supplement 2
Functional decoding of the human left (A) and right (B) inferior parietal lobule (IPL) subregions.
(C) Differences between the correlation values of the left and right IPL subregions.
Figure 2
Structural allometric scaling and asymmetries of the inferior parietal lobule (IPL) subregions across species.
(A) Volumes of the IPL subregions plotted against total cortical gray matter volume (GMV). Solid lines represent the best fit using mean macaque, chimpanzee, and human data points; dotted lines …
Figure 3 with 1 supplement
Connectional asymmetries of the IPL subdivisions in the vertex-wise analyses across species.
Effect size (Cohen’s d) related to asymmetric connections of IPL subdivisions displayed on the left hemisphere of a species-specific standard brain (leftward asymmetry: yellow, rightward asymmetry: …
Figure 3—figure supplement 1
Connectivity profiles of IPL subdivisions across species.
Probabilistic tractography was performed for each IPL subdivision to map its whole-brain connectivity profiles. The group tractograms shown were at a threshold of 0.3 for macaques, 0.2 for …
Figure 4 with 2 supplements
Regional connectional asymmetries of IPL subdivisions.
(A) Connectional asymmetries of IPL subdivisions in the region of interest (ROI)-wise analyses across species. Connectional asymmetry was calculated for the connections between each IPL subregion …
Figure 4—figure supplement 1
Bar graphs of the average connectivity values between the inferior parietal lobule (IPL) subregions and 11 cortical regions for each species.
The error bars indicate standard deviation. *Significance at a Bonferroni-corrected level of p<0.05.
Figure 4—figure supplement 2
Bar graphs of the average connectivity values between the inferior parietal lobule (IPL) subregions and 11 subcortical tracts for each species.
The error bars indicate standard deviation. *Significance at a Bonferroni-corrected level of p<0.05.
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