Studying evolution of the primary body axis in vivo and in vitro

  1. Kerim Anlas
  2. Vikas Trivedi  Is a corresponding author
  1. EMBL Barcelona, Spain
  2. EMBL Heidelberg, Developmental Biology, Germany
3 figures

Figures

Primary axis formation during gastrulation in metazoan embryos and corresponding artificial systems.

Metazoan embryos around the gastrulation or an equivalent developmental phase exhibit distinct morphologies and associated overall tissue rearrangement dynamics. Yet, during this event they …

Diverse developmental trajectories accessible to ESC(-LP)s in the presence and absence of extraembryonic inputs.

Compared to the native embryo, (re-) aggregation of ESC-LPs reveals potentially alternative developmental modes to the same body plan. Evidence for this has been found in Nematostella reaggregates …

A conserved developmental mode emerges upon removal of species-specific extraembryonic environments.

The developmental trajectories which aggregates of ESC(-LP)s exhibit upon removal of external or extraembryonic and associated boundaries may constitute a conserved mode that is shared across …

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