Smartphone screen testing, a novel pre-diagnostic method to identify SARS-CoV-2 infectious individuals
- Diagnosis Biotech, Chile
- Institute of Ophthalmology, University College London, United Kingdom
- Grupo Oncológico Cooperativo Chileno de Investigación, Chile
- Laboratorio de Especialidad, Clínica Dávila, Chile
- Laboratory of Chemical Carcinogenesis and Pharmacogenetics (Chilean Health Council Diagnostic Covid19 Laboratory), Department of Basic and Clinical Oncology, Faculty of Medicine, University of Chile, Chile
- Centro de Biotecnología Acuícola, Facultad de Química y Biología, Chile
- Programa Disciplinario de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Chile
- Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Chile
- Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Spain
- Facultad de Medicina Veterinaria y Agronomía, Universidad de Las Américas, Chile
- Department of Microbiology, Virology and Infection Control, Hospital National Health Service Foundation Trust, United Kingdom
- National Institute for Health Research Biomedical Research Centre at Great Ormond Hospital for Children National Health Service Foundation Trust and University College, United Kingdom
Figures
Figure 1 with 2 supplements
Phone Screen Testing and RT-PCR can identify individuals with high SARS-CoV-2 viral load.
(A) Schematic of smartphone sampling. Swabbing follows the dashed line indicated trajectory. (B, D) Histograms showing the distribution of individuals on ranges of clinical RT-PCR Ct value results …
Figure 1—figure supplement 1
Pilot and validation study cohort data analysis.
(A, B) Two-by-two tables for sensitivity and specificity of PoST method compared to nasopharyngeal RT-PCR results in the (A) pilot cohort (Source data 1) and (B) validation cohort (Source data 2). (C…
Figure 1—figure supplement 2
SARS-CoV2-19 RT-PCR cycle threshold (Ct) values in Chilean individuals.
(A–H) Histograms representing the Ct value distribution of the patients from Dávila Clinic (Santiago, Chile) between March and October 2020 (n = 7569, Source data 3).
Additional files
-
Source data 1
Tab 1 including all data generated by the 2020 cohort study.
- https://cdn.elifesciences.org/articles/70333/elife-70333-data1-v2.xlsx
-
Source data 2
Tab 2 including all data generated by the 2020 cohort study.
- https://cdn.elifesciences.org/articles/70333/elife-70333-data2-v2.xlsx
-
Source data 3
Tab 1 including all data generated by the 2020 cohort study.
- https://cdn.elifesciences.org/articles/70333/elife-70333-data3-v2.xlsx
-
Transparent reporting form
- https://cdn.elifesciences.org/articles/70333/elife-70333-transrepform-v2.pdf
