(A) Venn diagram displaying genes included in the fingerprinting (120) predominantly expressed in the endometrium based on Human Protein Atlas data that overlap with genes modulated by ESR1 described by Hewitt et al., 2010 and genes associated with PGR silencing described by Mazur et al., 2015. (B) Network showing the connections between proteins codified by DD fingerprinting and the hormonal receptors, ER1 and PR. Shapes indicate different clusters established by String k-means method. Squares, cluster involved in gland morphogenesis and cell migration; circles, cluster involved in extracellular matrix organization and stromal cell differentiation; hexagons; cluster involved in cellular response to DNA damage and regulation of cell cycle. Color gradient indicate gene expression in terms of log2FC. Hub genes are shown with an asterisk. (C-H) Gene expression levels of IHH, MSX2, ESR1, PGR, PGR-A, and PGR-B assessed for sPE (n=13) vs. controls (n=9) by RT-qPCR (gray bars, control; green bars, sPE). RT-qPCR values are expressed as mean± SE. *** p<0.001, ** p<0.01, *p<0.05. (I-J) Tissue sections of control (n=4) and sPE (n=4) endometrium during late secretory phase were immunostained with antibody against ER1 or PR. Nuclei were visualized with DAPI. Scale bar: 50 µM.