Models were adjusted for age, sex, region, education, household income, occupation, marital status, tea-drinking habit, smoking status, alcohol intake, physical activity, self-rated health, fasting …
Significant associations of egg consumption and metabolic markers, and associations of these markers with risks of CVD.
Yellow dots represented markers that were associated with egg consumption but not with the risk of diseases. Blue dots represented markers associated with the risk of diseases but not with egg …
Global comparison of SD differences of 225 log-transformed metabolic markers associated with weekly days of egg consumption and CVD risks.
(A) In basic models, additionally adjusted for (B) BMI, (C) hypertension, (D) diabetes, and (E) family history of diabetes, heart attack or stroke. Significance: * p<0.05, ** p<0.01 (FDR-adjusted p …
Controls | MI cases | IS cases | ICH cases | |
---|---|---|---|---|
N | 1,377 | 946 | 1217 | 1238 |
Age, y | 46.87 (0.20) | 52.42 (0.24) | 42.51 (0.22) | 47.38 (0.21) |
Female, % | 50.26 | 40.40 | 55.87 | 51.54 |
Urban residents, % | 27.13 | 28.90 | 36.88 | 23.37 |
Middle school or above, % | 56.97 | 53.84 | 53.70 | 56.36 |
Income ≥35,000 Yuan/year, % | 9.98 | 12.84 | 12.89 | 10.60 |
Manual worker, % | 69.88 | 68.39 | 69.12 | 71.50 |
BMI, kg/m2 | 23.56 (0.09) | 24.03 (0.12) | 24.27 (0.10) | 24.20 (0.10) |
SBP, mmHg | 127.94 (0.64) | 136.96 (0.82) | 136.46 (0.72) | 149.76 (0.68) |
DBP, mmHg | 76.97 (0.36) | 82.05 (0.47) | 82.57 (0.41) | 89.35 (0.39) |
RBG, mmol/L | 5.63 (0.08) | 6.47 (0.10) | 6.19 (0.08) | 6.31 (0.08) |
Ever regular smoking, % | 34.60 | 40.79 | 38.32 | 36.10 |
Weekly drinking, % | 18.11 | 15.27 | 18.77 | 20.68 |
Physical activity, MET-h/d | 23.20 (0.36) | 22.08 (0.46) | 22.72 (0.40) | 23.26 (0.38) |
Eggs consumption, d/w | 2.69 (0.06) | 2.44 (0.07) | 2.62 (0.07) | 2.52 (0.06) |
Red meat consumption, d/w | 3.26 (0.06) | 3.23 (0.07) | 3.35 (0.06) | 3.31 (0.06) |
Fresh fruits consumption, d/w | 2.32 (0.05) | 1.91 (0.07) | 2.08 (0.06) | 2.04 (0.06) |
≥8 h of fasting, % | 13.65 | 15.04 | 16.69 | 14.86 |
Poor self-rated health, % | 9.60 | 14.00 | 14.11 | 13.49 |
Diabetes, % | 5.27 | 10.86 | 8.74 | 8.21 |
Hypertension, % | 27.06 | 44.47 | 45.00 | 64.66 |
Family history of diabetes, % | 7.22 | 9.02 | 9.11 | 7.98 |
Family history of CVD, % | 23.68 | 27.55 | 26.71 | 31.04 |
Results were standardized by age, sex, and region where appropriate. Values are means (standard errors, SE) or %. Abbreviations: BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; RBG, random blood glucose; MET, metabolic equivalent; CVD, cardiovascular disease; MI, myocardial infarction; IS, ischemic stroke; ICH, intracerebral hemorrhage.
Detailed association of egg consumption, metabolic markers, and CVD risk.
(a) Associations (95% CI) of egg consumption with all 225 log-transformed metabolic markers or devided traits, and of these markers with CVD risk. (b). ORs (95% CI) for MI, IS, and ICH per SD higher log-transformed metabolic markers.
Members of the China Kadoorie Biobank collaborative group.
Analysis code based on Stata software.