Epidemiology and Global Health

Latest articles

1. 1. Epidemiology and Global Health

   COVID-19 pandemic dynamics in South Africa and epidemiological characteristics of three variants of concern (Beta, Delta, and Omicron)

   Wan Yang, Jeffrey L Shaman

   Model-inference reconstructed SARS-CoV-2 transmission dynamics in South Africa during March 2020 to February 2022, and quantified the immune erosion potential and transmissibility of three major variants (Beta, Delta, and Omicron), highlighting their common characteristics and the need for more proactive preparedness.
2. 1. Epidemiology and Global Health

   Adiposity may confound the association between vitamin D and disease risk – a lifecourse Mendelian randomization study

   Tom G Richardson et al.

   Genetic analyses provide evidence that adiposity influences vitamin D levels at different timepoints over the lifecourse, suggesting that associations previously reported between vitamin D deficiency and disease by conventional epidemiological studies may have been prone to confounding.
3. 1. Epidemiology and Global Health
   2. Microbiology and Infectious Disease

   Estimation and worldwide monitoring of the effective reproductive number of SARS-CoV-2

   Jana Sanne Huisman et al.
4. 1. Epidemiology and Global Health
   2. Evolutionary Biology

   Estimating the potential to prevent locally acquired HIV infections in a UNAIDS Fast-Track City, Amsterdam

   Alexandra Blenkinsop et al.
5. 1. Epidemiology and Global Health
   2. Evolutionary Biology

   Genomic epidemiology of the first two waves of SARS-CoV-2 in Canada

   Angela McLaughlin et al.

   Canadian COVID-19 travel restrictions imposed in March 2020 greatly reduced SARS-CoV-2 importations, but were insufficient to prevent new sublineages of similar transmissibility from being introduced and replacing early sublineages.
6. 1. Epidemiology and Global Health
   2. Genetics and Genomics

   Integrated analyses of growth differentiation Factor-15 concentration and cardiometabolic diseases in humans

   Susanna Lemmelä et al.
7. 1. Computational and Systems Biology
   2. Epidemiology and Global Health

   The unmitigated profile of COVID-19 infectiousness

   Ron Sender et al.
8. 1. Epidemiology and Global Health
   2. Genetics and Genomics

   Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations

   Fei Chen et al.

   A previously developed multi-ancestry polygenic risk score is potentially an effective prostate cancer risk stratification tool across ancestry populations.
9. 1. Epidemiology and Global Health

   Population-based sequencing of Mycobacterium tuberculosis reveals how current population dynamics are shaped by past epidemics

   Irving Cancino-Muñoz et al.

   Low-burden does not mean low local transmission, and tailor-made strategies are needed to control TB based on the knowledge of the local transmission dynamics.
10. 1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study

    Charles N Agoti et al.

    Genomic analysis of initial SARS-CoV-2 waves in Kenya revealed Mombasa City as a key gateway for variants entering Coastal Kenya with onward inter-county transmission highlighting significance of surveillance in major cities for early warning of lineages entering local populations.