1. Genetics and Genomics

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

  1. Joseph M Replogle
  2. Jessica L Bonnar
  3. Angela N Pogson
  4. Christina R Liem
  5. Nolan K Maier
  6. Yufang Ding
  7. Baylee J Russell
  8. Xingren Wang
  9. Kun Leng
  10. Alina Guna
  11. Thomas M Norman
  12. Ryan A Pak
  13. Daniel M Ramos
  14. Michael Emmerson Ward
  15. Luke A Gilbert
  16. Martin Kampmann
  17. Jonathan S Weissman  Is a corresponding author
  18. Marco Jost  Is a corresponding author
  1. University of California, San Francisco, United States
  2. Whitehead Institute for Biomedical Research, United States
  3. Harvard Medical School, United States
  4. National Institutes of Health, United States
  5. National Institute of Neurological Disorders and Stroke, United States
https://doi.org/10.7554/eLife.81856
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  1. Joseph M Replogle
  2. Jessica L Bonnar
  3. Angela N Pogson
  4. Christina R Liem
  5. Nolan K Maier
  6. Yufang Ding
  7. Baylee J Russell
  8. Xingren Wang
  9. Kun Leng
  10. Alina Guna
  11. Thomas M Norman
  12. Ryan A Pak
  13. Daniel M Ramos
  14. Michael Emmerson Ward
  15. Luke A Gilbert
  16. Martin Kampmann
  17. Jonathan S Weissman
  18. Marco Jost
(2022)
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
eLife 11:e81856.
https://doi.org/10.7554/eLife.81856
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  1. Joseph M Replogle
  2. Jessica L Bonnar
  3. Angela N Pogson
  4. Christina R Liem
  5. Nolan K Maier
  6. Yufang Ding
  7. Baylee J Russell
  8. Xingren Wang
  9. Kun Leng
  10. Alina Guna
  11. Thomas M Norman
  12. Ryan A Pak
  13. Daniel M Ramos
  14. Michael Emmerson Ward
  15. Luke A Gilbert
  16. Martin Kampmann
  17. Jonathan S Weissman
  18. Marco Jost
(2022)
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
eLife 11:e81856.
https://doi.org/10.7554/eLife.81856