1. Neuroscience

Balancing true and false detection of intermittent sensory targets by adjusting the inputs to the evidence accumulation process

  1. Anna Catharina Geuzebroek  Is a corresponding author
  2. Hannah Craddock
  3. Redmond G O'Connell
  4. Simon P Kelly  Is a corresponding author
  1. University College Dublin, Ireland
  2. Trinity College Dublin, Ireland
https://doi.org/10.7554/eLife.83025
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  1. Anna Catharina Geuzebroek
  2. Hannah Craddock
  3. Redmond G O'Connell
  4. Simon P Kelly
(2023)
Balancing true and false detection of intermittent sensory targets by adjusting the inputs to the evidence accumulation process
eLife 12:e83025.
https://doi.org/10.7554/eLife.83025
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Abstract

Decisions about noisy stimuli are widely understood to be made by accumulating evidence up to a decision bound that can be adjusted according to task demands. However, relatively little is known about how such mechanisms operate in continuous monitoring contexts requiring intermittent target detection. Here, we examined neural decision processes underlying detection of 1-second coherence-targets within continuous random dot motion, and how they are adjusted across contexts with Weak, Strong, or randomly Mixed Weak/Strong targets. Our prediction was that decision bounds would be set lower when Weak targets are more prevalent. Behavioural hit and false alarm rate patterns were consistent with this, and were well-captured by a bound-adjustable leaky accumulator model. However, Beta-band EEG signatures of motor preparation contradicted this, instead indicating lower bounds in the Strong-target context. We thus tested two alternative models in which decision bound dynamics were constrained directly by Beta measurements, respectively featuring leaky accumulation with adjustable leak, and non-leaky accumulation of evidence referenced to an adjustable sensory-level criterion. We found that the latter model best explained both behaviour and neural dynamics, highlighting novel means of decision policy regulation and the value of neurally-informed modelling.

Data availability

Code to recreated the Random Dot Motion task utilising Psychtoolbox is publicly available at https://github.com/AnnaCGeuzebroek/Context-Dependent-Detection. All code to recreated the behavioural and EEG data analysis as well as the modelling code can be found at https://github.com/AnnaCGeuzebroek/Continuous-Behavioural-Modelling. Pre-processed anonymised EEG and behavioural data is uploaded at OSFhttps://osf.io/yjvku/?view_only=7ed5aee5d09a4d5ca13de1ba169b0588

Article and author information

Author details

  1. Anna Catharina Geuzebroek

    School of Electrical and Electronic Engineering, University College Dublin, Dublin, Ireland
    For correspondence
    anna.geuzebroek@ucd.ie
    Competing interests
    No competing interests declared.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0002-8287-2990

  2. Hannah Craddock

    School of Electrical and Electronic Engineering, University College Dublin, Dublin, Ireland
    Competing interests
    No competing interests declared.

  3. Redmond G O'Connell

    Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Competing interests
    Redmond G O'Connell, Reviewing editor, eLife.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-6949-2793

  4. Simon P Kelly

    School of Electrical and Electronic Engineering, University College Dublin, Dublin, Ireland
    For correspondence
    simon.kelly@ucd.ie
    Competing interests
    No competing interests declared.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-9983-3595

Funding

Science Fundation Ireland (15/CDA/3591)

  • Anna Catharina Geuzebroek
  • Simon P Kelly

Wellcome Trust (219572/Z/19/Z)

  • Anna Catharina Geuzebroek
  • Simon P Kelly

Horizon 2020 European Research Council Consolidator Grant Ind (865474)

  • Redmond G O'Connell

The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.

Ethics

Human subjects: All participants gave written consent prior to their participation and were compensated for their time with €25. The UCD Human Research Ethics Committee for Life Sciences approved all experimental procedures in accordance with the Declaration of Helsinki (LS-16-76-Craddock).

Copyright

© 2023, Geuzebroek et al.

This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

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  1. Anna Catharina Geuzebroek
  2. Hannah Craddock
  3. Redmond G O'Connell
  4. Simon P Kelly
(2023)
Balancing true and false detection of intermittent sensory targets by adjusting the inputs to the evidence accumulation process
eLife 12:e83025.
https://doi.org/10.7554/eLife.83025

Share this article

https://doi.org/10.7554/eLife.83025

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