Spatiotemporal neural dynamics of object recognition under uncertainty in humans
Abstract
While there is a wealth of knowledge about core object recognition-our ability to recognize clear, high-contrast object images, how the brain accomplishes object recognition tasks under increased uncertainty remains poorly understood. We investigated the spatiotemporal neural dynamics underlying object recognition under increased uncertainty by combining MEG and 7 Tesla fMRI in humans during a threshold-level object recognition task. We observed an early, parallel rise of recognition-related signals across ventral visual and frontoparietal regions that preceded the emergence of category-related information. Recognition-related signals in ventral visual regions were best explained by a two-state representational format whereby brain activity bifurcated for recognized and unrecognized images. By contrast, recognition-related signals in frontoparietal regions exhibited a reduced representational space for recognized images, yet with sharper category information. These results provide a spatiotemporally resolved view of neural activity supporting object recognition under uncertainty, revealing a pattern distinct from that underlying core object recognition.
Data availability
The analysis code, data and code to reproduce all figures can be downloaded athttps://github.com/BiyuHeLab/HLTP_Fusion_Wu2022/tree/submission
Article and author information
Author details
Funding
National Institutes of Health (R01EY032085)
- Biyu J He
The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.
Reviewing Editor
- Huan Luo, Peking University, China
Ethics
Human subjects: Data collection procedures followed protocols approved by the institutional review boards of the intramural research program of NINDS/NIH (protocol #14 N-0002) and NYU Grossman School of Medicine (protocol s15-01323). All participants provided written informed consent.
Version history
- Received: November 9, 2022
- Preprint posted: November 17, 2022 (view preprint)
- Accepted: May 12, 2023
- Accepted Manuscript published: May 15, 2023 (version 1)
- Version of Record published: May 31, 2023 (version 2)
Copyright
© 2023, Wu et al.
This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.
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