(A) A schematic showing LPS-mediated activation of human macrophages. (B) A plot showing changes in the levels of 191 secreted factors in response to LPS stimulation. Significantly increased or … see more
(A) Plots showing leave-one-out cross validation (LOOCV) error using elastic net regularization fit for OPN (left) and CCL4 (right). The error bars represent cross-validation error plus 1 SD. The … see more
(A) KinCytE offers three sections for users to explore potential cytokine(s) or chemokine(s) inhibiting drugs (Identify Drugs), related kinases (Identify Kinase), and cytokine signaling network … see more
Fold change of average cytokine level in LPS-treated macrophage compared to control.
Percentage changes in cytokine level in kinase inhibitor-treated macrophages compared to control.
Summary table of predicted kinases involved in cytokine models.
Predicted cytokine levels in macrophares treated with kinase inhibitors.